JPH0133445B2 - - Google Patents
Info
- Publication number
- JPH0133445B2 JPH0133445B2 JP51121183A JP12118376A JPH0133445B2 JP H0133445 B2 JPH0133445 B2 JP H0133445B2 JP 51121183 A JP51121183 A JP 51121183A JP 12118376 A JP12118376 A JP 12118376A JP H0133445 B2 JPH0133445 B2 JP H0133445B2
- Authority
- JP
- Japan
- Prior art keywords
- globules
- drug
- albumin
- release
- percent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 108010088751 Albumins Proteins 0.000 claims description 60
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- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 claims description 25
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- 210000002966 serum Anatomy 0.000 description 1
- 229960004025 sodium salicylate Drugs 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 229960004306 sulfadiazine Drugs 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 239000013595 supernatant sample Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 229960005371 tolbutamide Drugs 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 239000000814 tuberculostatic agent Substances 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62114575A | 1975-10-09 | 1975-10-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5247912A JPS5247912A (en) | 1977-04-16 |
| JPH0133445B2 true JPH0133445B2 (https=) | 1989-07-13 |
Family
ID=24488920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51121183A Granted JPS5247912A (en) | 1975-10-09 | 1976-10-08 | Solid serum albumin circles and its production |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4147767A (https=) |
| JP (1) | JPS5247912A (https=) |
| AU (1) | AU513080B2 (https=) |
| CA (1) | CA1077842A (https=) |
| CH (1) | CH629666A5 (https=) |
| DE (1) | DE2645553C2 (https=) |
| FR (1) | FR2326934A1 (https=) |
| GB (1) | GB1567763A (https=) |
| SE (1) | SE443086B (https=) |
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| CN107205938A (zh) | 2014-12-18 | 2017-09-26 | 温德加普医疗股份有限公司 | 用于溶解或增溶治疗剂的方法和组合物 |
| US11628208B2 (en) | 2015-10-05 | 2023-04-18 | The Corporation Of Mercer University | System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins |
| WO2017062463A1 (en) | 2015-10-05 | 2017-04-13 | The Corporation Of Mercer University | Nanospheres encapsulating bioactive material and method for formulation of nanospheres |
| CN109311802B (zh) * | 2016-05-26 | 2022-02-08 | 珠海贝海生物技术有限公司 | 苯丁酸氮芥制剂 |
| CN115887677B (zh) * | 2022-11-03 | 2024-04-12 | 嘉兴学院 | 一种蛋白质仿生胶囊的制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3265629A (en) * | 1958-12-22 | 1966-08-09 | Ncr Co | Coating by phase separation |
| US3265630A (en) * | 1958-12-22 | 1966-08-09 | Ncr Co | Encapsulating lipophilic material by coacervation |
| US3043782A (en) * | 1958-12-22 | 1962-07-10 | Upjohn Co | Process for preparing a more impermeable coating by liquid-liquid phase separation |
| US3533958A (en) * | 1966-07-22 | 1970-10-13 | Ncr Co | Process for making minute capsules |
| US3663685A (en) * | 1968-04-01 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable radioactive particles |
| US3663686A (en) * | 1968-04-24 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable radioactive particles |
| US3663687A (en) * | 1968-06-26 | 1972-05-16 | Minnesota Mining & Mfg | Biodegradable parenteral microspherules |
| US3541201A (en) * | 1968-12-18 | 1970-11-17 | Ethan Alan Brown | Novel sodium chloride encapsulated injectionable substances |
| US3937668A (en) * | 1970-07-15 | 1976-02-10 | Ilse Zolle | Method for incorporating substances into protein microspheres |
-
1976
- 1976-08-31 CA CA260,288A patent/CA1077842A/en not_active Expired
- 1976-10-06 SE SE7611064A patent/SE443086B/xx not_active IP Right Cessation
- 1976-10-08 AU AU18506/76A patent/AU513080B2/en not_active Expired
- 1976-10-08 FR FR7630396A patent/FR2326934A1/fr active Granted
- 1976-10-08 JP JP51121183A patent/JPS5247912A/ja active Granted
- 1976-10-08 GB GB42007/76A patent/GB1567763A/en not_active Expired
- 1976-10-08 DE DE2645553A patent/DE2645553C2/de not_active Expired
- 1976-10-08 CH CH1276476A patent/CH629666A5/de not_active IP Right Cessation
-
1977
- 1977-09-30 US US05/838,355 patent/US4147767A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2326934A1 (fr) | 1977-05-06 |
| AU1850676A (en) | 1978-04-13 |
| AU513080B2 (en) | 1980-11-13 |
| CH629666A5 (de) | 1982-05-14 |
| GB1567763A (en) | 1980-05-21 |
| CA1077842A (en) | 1980-05-20 |
| SE443086B (sv) | 1986-02-17 |
| SE7611064L (sv) | 1977-04-10 |
| FR2326934B1 (https=) | 1979-07-20 |
| US4147767A (en) | 1979-04-03 |
| DE2645553C2 (de) | 1986-11-06 |
| JPS5247912A (en) | 1977-04-16 |
| DE2645553A1 (de) | 1977-04-21 |
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