JP7782046B2 - ピラゾロン化合物及びピラゾロン化剤 - Google Patents

ピラゾロン化合物及びピラゾロン化剤

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Publication number
JP7782046B2
JP7782046B2 JP2024537730A JP2024537730A JP7782046B2 JP 7782046 B2 JP7782046 B2 JP 7782046B2 JP 2024537730 A JP2024537730 A JP 2024537730A JP 2024537730 A JP2024537730 A JP 2024537730A JP 7782046 B2 JP7782046 B2 JP 7782046B2
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Japan
Prior art keywords
group
carbon atoms
optionally substituted
compound
substituted
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JP2024537730A
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English (en)
Japanese (ja)
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JPWO2024024760A1 (https=
JPWO2024024760A5 (https=
Inventor
賢二 大隅
浩太朗 後藤
正斗 筒井
真盛 水野
杉　智和
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Noguchi Institute
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Noguchi Institute
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Publication of JPWO2024024760A5 publication Critical patent/JPWO2024024760A5/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • C07D231/24—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms having sulfone or sulfonic acid radicals in the molecule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2024537730A 2022-07-25 2023-07-25 ピラゾロン化合物及びピラゾロン化剤 Active JP7782046B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022118259 2022-07-25
JP2022118259 2022-07-25
PCT/JP2023/027102 WO2024024760A1 (ja) 2022-07-25 2023-07-25 ピラゾロン化合物及びピラゾロン化剤

Publications (3)

Publication Number Publication Date
JPWO2024024760A1 JPWO2024024760A1 (https=) 2024-02-01
JPWO2024024760A5 JPWO2024024760A5 (https=) 2024-11-12
JP7782046B2 true JP7782046B2 (ja) 2025-12-08

Family

ID=89706371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537730A Active JP7782046B2 (ja) 2022-07-25 2023-07-25 ピラゾロン化合物及びピラゾロン化剤

Country Status (4)

Country Link
US (1) US20250129030A1 (https=)
EP (1) EP4563572A1 (https=)
JP (1) JP7782046B2 (https=)
WO (1) WO2024024760A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003059547A (ja) 2001-08-17 2003-02-28 Nippon Kayaku Co Ltd 色素増感光電変換素子
JP2005015750A (ja) 2003-06-24 2005-01-20 Yamada Chem Co Ltd ペリミジン化合物
WO2006129583A1 (ja) 2005-05-30 2006-12-07 Genecare Research Institute Co., Ltd. ピラゾロン誘導体
WO2006129587A1 (ja) 2005-05-30 2006-12-07 Genecare Research Institute Co., Ltd. ピラゾロン誘導体を含有する医薬組成物
JP2009093909A (ja) 2007-10-09 2009-04-30 Konica Minolta Business Technologies Inc 色素増感光電変換素子及びその製造方法
CN110128345A (zh) 2019-05-13 2019-08-16 上海大学 一种吡唑酮衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5980470A (ja) * 1982-10-29 1984-05-09 Konishiroku Photo Ind Co Ltd オキソノ−ル染料の製造方法
JP2852685B2 (ja) * 1990-04-06 1999-02-03 コニカ株式会社 ハロゲン化銀カラー写真感光材料
JPH0485538A (ja) * 1990-07-28 1992-03-18 Konica Corp ハロゲン化銀カラー写真感光材料
JPH08229302A (ja) * 1995-02-24 1996-09-10 Konica Corp 固体微粒子の製造方法および製造装置

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003059547A (ja) 2001-08-17 2003-02-28 Nippon Kayaku Co Ltd 色素増感光電変換素子
JP2005015750A (ja) 2003-06-24 2005-01-20 Yamada Chem Co Ltd ペリミジン化合物
WO2006129583A1 (ja) 2005-05-30 2006-12-07 Genecare Research Institute Co., Ltd. ピラゾロン誘導体
WO2006129587A1 (ja) 2005-05-30 2006-12-07 Genecare Research Institute Co., Ltd. ピラゾロン誘導体を含有する医薬組成物
JP2009093909A (ja) 2007-10-09 2009-04-30 Konica Minolta Business Technologies Inc 色素増感光電変換素子及びその製造方法
CN110128345A (zh) 2019-05-13 2019-08-16 上海大学 一种吡唑酮衍生物的制备方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANGELASTRO, Antonio et al.，Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug-to- A，ChemSusChem，2022年01月20日，15, e202102592，pp.1-4，DOI: 10.1002/cssc.202102592
JANSON, Nils et al.，Bifunctional Reagents for Formylglycine Conjugation: Pitfalls and Breakthroughs，ChemBioChem，2020年09月18日，21，pp.3580-3593，DOI: 10.1002/cbic.202000416
KUDIRKA, Romas A. et al.，Site-Specific Tandem Knoevenagel Condensation-Michael Addition To Generate Antibody-Drug Conjugates，ACS Med. Chem. Lett.，2016年08月30日，7，pp.994-998，DOI: 10.1021/acsmedchemlett.6b00253

Also Published As

Publication number Publication date
EP4563572A1 (en) 2025-06-04
WO2024024760A1 (ja) 2024-02-01
JPWO2024024760A1 (https=) 2024-02-01
US20250129030A1 (en) 2025-04-24

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