JP7779905B2 - ホログラフィー装置及び細胞の評価方法 - Google Patents

ホログラフィー装置及び細胞の評価方法

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Publication number
JP7779905B2
JP7779905B2 JP2023512907A JP2023512907A JP7779905B2 JP 7779905 B2 JP7779905 B2 JP 7779905B2 JP 2023512907 A JP2023512907 A JP 2023512907A JP 2023512907 A JP2023512907 A JP 2023512907A JP 7779905 B2 JP7779905 B2 JP 7779905B2
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image
interference
light
phase
object light
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JPWO2022215499A1 (https=
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英紀 安田
龍介 大▲崎▼
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Fujifilm Corp
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Fujifilm Corp
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    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/22—Processes or apparatus for obtaining an optical image from holograms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453—Holographic interferometry
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/14—Condensers affording illumination for phase-contrast observation
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/02—Details of features involved during the holographic process; Replication of holograms without interference recording
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0486—Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/08—Synthesising holograms, i.e. holograms synthesized from objects or objects from holograms
    • G03H1/0866—Digital holographic imaging, i.e. synthesizing holobjects from holograms
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005—Adaptation of holography to specific applications
    • G03H2001/005—Adaptation of holography to specific applications in microscopy, e.g. digital holographic microscope [DHM]
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
    • G03H2001/0452—Digital holography, i.e. recording holograms with digital recording means arranged to record an image of the object
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04—Processes or apparatus for producing holograms
    • G03H1/0486—Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations
    • G03H2001/0491—Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations by monitoring the hologram formation, e.g. via a feed-back loop
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2210/00—Object characteristics
    • G03H2210/10—Modulation characteristics, e.g. amplitude, phase, polarisation
    • G03H2210/12—Phase modulating object, e.g. living cell
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2222/00—Light sources or light beam properties
    • G03H2222/31—Polarised light
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2223/00—Optical components
    • G03H2223/20—Birefringent optical element, e.g. wave plate
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2223/00—Optical components
    • G03H2223/22—Polariser
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2227/00—Mechanical components or mechanical aspects not otherwise provided for
    • G03H2227/03—Means for moving one component
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Computing Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
JP2023512907A 2021-04-09 2022-03-18 ホログラフィー装置及び細胞の評価方法 Active JP7779905B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021066769 2021-04-09
JP2021066769 2021-04-09
PCT/JP2022/012806 WO2022215499A1 (ja) 2021-04-09 2022-03-18 ホログラフィー装置及び細胞の評価方法

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JPWO2022215499A1 JPWO2022215499A1 (https=) 2022-10-13
JP7779905B2 true JP7779905B2 (ja) 2025-12-03

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US (1) US12591203B2 (https=)
EP (1) EP4321936A4 (https=)
JP (1) JP7779905B2 (https=)
CN (1) CN117098987A (https=)
WO (1) WO2022215499A1 (https=)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008123408A1 (ja) 2007-04-04 2008-10-16 Nikon Corporation ３次元顕微鏡および３次元画像取得方法
JP2013531787A (ja) 2010-05-25 2013-08-08 アリックス インコーポレイテッド 粒子の運動度および／または細胞の分散を求めるためのホログラフィック変動顕微鏡装置および方法
JP2014010019A (ja) 2012-06-28 2014-01-20 Nikon Corp 干渉計測装置
US20170356846A1 (en) 2014-12-17 2017-12-14 Commissariat à I'énergie atomique et aux énergies alternatives System for observing objects
WO2018147473A1 (ja) 2017-02-10 2018-08-16 国立大学法人京都工芸繊維大学 ３次元物体情報計測装置
WO2019176427A1 (ja) 2018-03-12 2019-09-19 富士フイルム株式会社 判定方法
WO2020261826A1 (ja) 2019-06-28 2020-12-30 富士フイルム株式会社 画像処理装置、評価システム、画像処理プログラム及び画像処理方法

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JPS58176511A (ja) * 1982-04-09 1983-10-17 Hitachi Ltd 干渉方法及びその装置
JPH04269603A (ja) * 1991-02-26 1992-09-25 Olympus Optical Co Ltd 干渉測定装置
JP2003015509A (ja) 2001-06-27 2003-01-17 Sony Corp 画像露光記録装置及び画像露光記録方法
CN101509813A (zh) * 2009-03-31 2009-08-19 昆明理工大学 旋转参考光偏振方向的数字全息光弹二维应力场检测方法
WO2014088089A1 (ja) * 2012-12-06 2014-06-12 合同会社３Ｄｒａｇｏｎｓ 三次元形状計測装置、ホログラム画像取得方法及び三次元形状計測方法
KR101990009B1 (ko) * 2017-08-25 2019-09-30 주식회사 내일해 개선된 홀로그래픽 복원 장치 및 방법
CN109946941A (zh) * 2019-04-17 2019-06-28 上海师范大学 基于Sagnac效应的干涉的光学图像加密系统及方法
CN110455799B (zh) * 2019-07-23 2022-06-17 长春理工大学 一种用于活细胞成像的高分辨率全息显微镜及方法
JP2021066769A (ja) 2019-10-18 2021-04-30 日鉄テックスエンジ株式会社 窯芯検知装置
CN112506019B (zh) * 2020-11-29 2022-05-03 北京工业大学 基于克罗内克积插值的离轴数字全息成像重建方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008123408A1 (ja) 2007-04-04 2008-10-16 Nikon Corporation ３次元顕微鏡および３次元画像取得方法
JP2013531787A (ja) 2010-05-25 2013-08-08 アリックス インコーポレイテッド 粒子の運動度および／または細胞の分散を求めるためのホログラフィック変動顕微鏡装置および方法
JP2014010019A (ja) 2012-06-28 2014-01-20 Nikon Corp 干渉計測装置
US20170356846A1 (en) 2014-12-17 2017-12-14 Commissariat à I'énergie atomique et aux énergies alternatives System for observing objects
WO2018147473A1 (ja) 2017-02-10 2018-08-16 国立大学法人京都工芸繊維大学 ３次元物体情報計測装置
WO2019176427A1 (ja) 2018-03-12 2019-09-19 富士フイルム株式会社 判定方法
WO2020261826A1 (ja) 2019-06-28 2020-12-30 富士フイルム株式会社 画像処理装置、評価システム、画像処理プログラム及び画像処理方法

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Publication number Publication date
WO2022215499A1 (ja) 2022-10-13
CN117098987A (zh) 2023-11-21
EP4321936A1 (en) 2024-02-14
JPWO2022215499A1 (https=) 2022-10-13
US20240027959A1 (en) 2024-01-25
EP4321936A4 (en) 2024-09-18
US12591203B2 (en) 2026-03-31

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