CN117098987A - 全息装置及细胞的评价方法 - Google Patents

全息装置及细胞的评价方法 Download PDF

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Publication number
CN117098987A
CN117098987A CN202280026344.2A CN202280026344A CN117098987A CN 117098987 A CN117098987 A CN 117098987A CN 202280026344 A CN202280026344 A CN 202280026344A CN 117098987 A CN117098987 A CN 117098987A
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China
Prior art keywords
image
object light
interference
light
phase
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Pending
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CN202280026344.2A
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English (en)
Chinese (zh)
Inventor
安田英纪
大崎龙介
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Fujifilm Corp
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Fujifilm Corp
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Publication of CN117098987A publication Critical patent/CN117098987A/zh
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    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/22Processes or apparatus for obtaining an optical image from holograms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N21/453Holographic interferometry
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/06Means for illuminating specimens
    • G02B21/08Condensers
    • G02B21/14Condensers affording illumination for phase-contrast observation
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/02Details of features involved during the holographic process; Replication of holograms without interference recording
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0443Digital holography, i.e. recording holograms with digital recording means
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0486Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/08Synthesising holograms, i.e. holograms synthesized from objects or objects from holograms
    • G03H1/0866Digital holographic imaging, i.e. synthesizing holobjects from holograms
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005Adaptation of holography to specific applications
    • G03H2001/005Adaptation of holography to specific applications in microscopy, e.g. digital holographic microscope [DHM]
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0443Digital holography, i.e. recording holograms with digital recording means
    • G03H2001/0452Digital holography, i.e. recording holograms with digital recording means arranged to record an image of the object
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/04Processes or apparatus for producing holograms
    • G03H1/0486Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations
    • G03H2001/0491Improving or monitoring the quality of the record, e.g. by compensating distortions, aberrations by monitoring the hologram formation, e.g. via a feed-back loop
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2210/00Object characteristics
    • G03H2210/10Modulation characteristics, e.g. amplitude, phase, polarisation
    • G03H2210/12Phase modulating object, e.g. living cell
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2222/00Light sources or light beam properties
    • G03H2222/31Polarised light
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2223/00Optical components
    • G03H2223/20Birefringent optical element, e.g. wave plate
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2223/00Optical components
    • G03H2223/22Polariser
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2227/00Mechanical components or mechanical aspects not otherwise provided for
    • G03H2227/03Means for moving one component
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Computing Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
CN202280026344.2A 2021-04-09 2022-03-18 全息装置及细胞的评价方法 Pending CN117098987A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021066769 2021-04-09
JP2021-066769 2021-04-09
PCT/JP2022/012806 WO2022215499A1 (ja) 2021-04-09 2022-03-18 ホログラフィー装置及び細胞の評価方法

Publications (1)

Publication Number Publication Date
CN117098987A true CN117098987A (zh) 2023-11-21

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CN202280026344.2A Pending CN117098987A (zh) 2021-04-09 2022-03-18 全息装置及细胞的评价方法

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US (1) US12591203B2 (https=)
EP (1) EP4321936A4 (https=)
JP (1) JP7779905B2 (https=)
CN (1) CN117098987A (https=)
WO (1) WO2022215499A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1466709A (zh) * 2001-06-27 2004-01-07 ���ṫ˾ 图象曝光记录装置及图象曝光记录方法
CN101509813A (zh) * 2009-03-31 2009-08-19 昆明理工大学 旋转参考光偏振方向的数字全息光弹二维应力场检测方法
US20150300803A1 (en) * 2012-12-06 2015-10-22 3Dragons, Llc Three-Dimensional Shape Measuring Device, Method for Acquiring Hologram Image, and Method for Measuring Three-Dimensional Shape
CN109946941A (zh) * 2019-04-17 2019-06-28 上海师范大学 基于Sagnac效应的干涉的光学图像加密系统及方法
CN110455799A (zh) * 2019-07-23 2019-11-15 长春理工大学 一种用于活细胞成像的高分辨率全息显微镜及方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58176511A (ja) * 1982-04-09 1983-10-17 Hitachi Ltd 干渉方法及びその装置
JPH04269603A (ja) * 1991-02-26 1992-09-25 Olympus Optical Co Ltd 干渉測定装置
US7633631B2 (en) 2007-04-04 2009-12-15 Nikon Corporation Three-dimensional microscope and method for obtaining three-dimensional image
WO2011149526A2 (en) 2010-05-25 2011-12-01 Arryx, Inc. Methods and apparatuses for detection of positional freedom of particles in biological and chemical analyses and applications in immunodiagnostics
JP2014010019A (ja) 2012-06-28 2014-01-20 Nikon Corp 干渉計測装置
FR3030748B1 (fr) 2014-12-17 2017-01-27 Commissariat Energie Atomique Systeme d'observation d'objets
JP6995376B2 (ja) 2017-02-10 2022-02-04 国立大学法人京都工芸繊維大学 3次元物体情報計測装置
KR101990009B1 (ko) * 2017-08-25 2019-09-30 주식회사 내일해 개선된 홀로그래픽 복원 장치 및 방법
EP3766984B1 (en) 2018-03-12 2024-10-30 FUJIFILM Corporation Determination method`
JP7026853B2 (ja) 2019-06-28 2022-02-28 富士フイルム株式会社 画像処理装置、評価システム、画像処理プログラム及び画像処理方法
JP2021066769A (ja) 2019-10-18 2021-04-30 日鉄テックスエンジ株式会社 窯芯検知装置
CN112506019B (zh) * 2020-11-29 2022-05-03 北京工业大学 基于克罗内克积插值的离轴数字全息成像重建方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1466709A (zh) * 2001-06-27 2004-01-07 ���ṫ˾ 图象曝光记录装置及图象曝光记录方法
CN101509813A (zh) * 2009-03-31 2009-08-19 昆明理工大学 旋转参考光偏振方向的数字全息光弹二维应力场检测方法
US20150300803A1 (en) * 2012-12-06 2015-10-22 3Dragons, Llc Three-Dimensional Shape Measuring Device, Method for Acquiring Hologram Image, and Method for Measuring Three-Dimensional Shape
CN109946941A (zh) * 2019-04-17 2019-06-28 上海师范大学 基于Sagnac效应的干涉的光学图像加密系统及方法
CN110455799A (zh) * 2019-07-23 2019-11-15 长春理工大学 一种用于活细胞成像的高分辨率全息显微镜及方法

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WO2022215499A1 (ja) 2022-10-13
EP4321936A1 (en) 2024-02-14
JPWO2022215499A1 (https=) 2022-10-13
US20240027959A1 (en) 2024-01-25
JP7779905B2 (ja) 2025-12-03
EP4321936A4 (en) 2024-09-18
US12591203B2 (en) 2026-03-31

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