JP7737219B2 - 潰瘍性大腸炎を治療するための方法 - Google Patents
潰瘍性大腸炎を治療するための方法Info
- Publication number
- JP7737219B2 JP7737219B2 JP2019505410A JP2019505410A JP7737219B2 JP 7737219 B2 JP7737219 B2 JP 7737219B2 JP 2019505410 A JP2019505410 A JP 2019505410A JP 2019505410 A JP2019505410 A JP 2019505410A JP 7737219 B2 JP7737219 B2 JP 7737219B2
- Authority
- JP
- Japan
- Prior art keywords
- subject
- pharmaceutical composition
- weeks
- treatment
- clostridium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022186548A JP2023010890A (ja) | 2016-08-03 | 2022-11-22 | 潰瘍性大腸炎を治療するための方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662370508P | 2016-08-03 | 2016-08-03 | |
| US62/370,508 | 2016-08-03 | ||
| US15/360,703 | 2016-11-23 | ||
| US15/360,703 US20180036352A1 (en) | 2016-08-03 | 2016-11-23 | Methods for treating ulcerative colitis |
| PCT/US2017/045092 WO2018026913A1 (en) | 2016-08-03 | 2017-08-02 | Methods for treating ulcerative colitis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022186548A Division JP2023010890A (ja) | 2016-08-03 | 2022-11-22 | 潰瘍性大腸炎を治療するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019525944A JP2019525944A (ja) | 2019-09-12 |
| JP2019525944A5 JP2019525944A5 (enExample) | 2020-09-17 |
| JP7737219B2 true JP7737219B2 (ja) | 2025-09-10 |
Family
ID=61071386
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019505410A Active JP7737219B2 (ja) | 2016-08-03 | 2017-08-02 | 潰瘍性大腸炎を治療するための方法 |
| JP2022186548A Pending JP2023010890A (ja) | 2016-08-03 | 2022-11-22 | 潰瘍性大腸炎を治療するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022186548A Pending JP2023010890A (ja) | 2016-08-03 | 2022-11-22 | 潰瘍性大腸炎を治療するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20180036352A1 (enExample) |
| EP (1) | EP3493822A1 (enExample) |
| JP (2) | JP7737219B2 (enExample) |
| CN (1) | CN109803667A (enExample) |
| AU (1) | AU2017306303B2 (enExample) |
| CA (1) | CA3032004A1 (enExample) |
| WO (1) | WO2018026913A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3045383B1 (fr) | 2015-12-18 | 2019-06-14 | Maat Pharma | Procede de lyophilisation d'un echantillon de microbiote fecal |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| EP3518946A4 (en) | 2016-09-27 | 2020-09-09 | Board of Regents, The University of Texas System | METHODS TO IMPROVE IMMUNE CHECKPOINT BLOCKING TREATMENT BY MODULATING THE MICROBIOME |
| CA3211208A1 (en) | 2017-04-03 | 2018-10-11 | Gusto Global, Llc | Rational design of microbial-based biotherapeutics |
| KR20200038506A (ko) | 2017-08-07 | 2020-04-13 | 핀치 테라퓨틱스, 인코포레이티드 | 건강한 장 장벽을 유지 및 회복시키기 위한 조성물 및 방법 |
| KR102118203B1 (ko) * | 2018-03-06 | 2020-06-02 | 주식회사 엠디헬스케어 | 코프로코커스 속 세균 유래 나노소포 및 이의 용도 |
| FR3078627B1 (fr) * | 2018-03-09 | 2020-11-13 | Maat Pharma | Procedure de collecte de selles et procede de preparation d'un echantillon pour transplantation de microbiote fecal |
| EP3597202A1 (en) * | 2018-07-20 | 2020-01-22 | Maat Pharma | Fecal microbiota composition, for use in reducing treatment-induced inflammation |
| CN113164527A (zh) * | 2018-09-27 | 2021-07-23 | 芬奇治疗控股有限责任公司 | 用于治疗癫痫和相关障碍的组合物和方法 |
| CN109394795A (zh) * | 2018-10-23 | 2019-03-01 | 上海市第十人民医院 | 一种肠菌胶囊制备方法及肠菌胶囊 |
| AU2019384816A1 (en) | 2018-11-21 | 2021-06-24 | Board Of Regents, The University Of Texas System | Methods and compositions for treating cancer |
| EP3911161A4 (en) * | 2019-01-16 | 2022-09-14 | Board of Regents, The University of Texas System | METHODS AND COMPOSITIONS FOR THE TREATMENT OF COLITIS-ASSOCIATED IMMUNE CHECKPOINT INHIBITOR |
| WO2021016081A1 (en) | 2019-07-19 | 2021-01-28 | Finch Therapeutics Holdings Llc. | Methods and products for treatment of gastrointestinal disorders |
| US20230087012A1 (en) * | 2020-02-14 | 2023-03-23 | Cornell University | Transferable microbiota for the treatment of ulcerative colitis |
| US11744866B2 (en) * | 2020-03-18 | 2023-09-05 | Sabine Hazan | Methods of preventing and treating COVID-19 infection with probiotics |
| US20220120746A1 (en) * | 2020-03-18 | 2022-04-21 | Sabine Hazan | Methods of Determining Susceptibility to COVID-19 Infection |
| CA3183811A1 (en) * | 2020-06-29 | 2022-01-06 | Marla C. DUBINSKY | Systems and methods for evaluating a subject for inflammatory bowel disease management |
| CN111888381A (zh) * | 2020-09-18 | 2020-11-06 | 广西细微生物科技有限责任公司 | 一种肠道微生物移植工艺 |
| JP2024501818A (ja) * | 2020-12-23 | 2024-01-16 | マー ファルマ | 微生物の複合群集を増殖させる方法 |
| CN113509494A (zh) * | 2021-09-06 | 2021-10-19 | 南京医科大学 | 普氏菌在制备治疗胆汁淤积性疾病的药物中的应用 |
| CN114246886B (zh) * | 2021-12-24 | 2023-05-30 | 山西大学 | 规则粪球菌在制备预防和治疗急性结肠炎的制剂中的应用 |
| CN115478031B (zh) * | 2022-09-28 | 2025-04-18 | 中国科学院深圳先进技术研究院 | 防治炎症性肠病的胆汁酸代谢菌及其应用 |
| KR20240114298A (ko) * | 2023-01-12 | 2024-07-23 | 에스엔제이 파마 인크 | 감염 저항성 장내 균주 및 그 용도 |
| CN119868571B (zh) * | 2025-01-23 | 2025-11-21 | 浙江大学 | 扭链瘤胃球菌及其修饰菌在制备治疗溃疡性结肠炎的产品中的应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004501095A (ja) | 2000-05-11 | 2004-01-15 | アンスティテュ ナショナール ド ラ ルシェルシュ アグロノミク | 消化器系障害の予防または治療のための水素依存性酢酸生成株の使用 |
| JP2016521704A (ja) | 2013-06-05 | 2016-07-25 | レビオティクス インコーポレイテッドRebiotix,Inc. | 微生物叢回復療法(mrt)、組成物および製造方法 |
Family Cites Families (161)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2828E (fr) | 1901-08-19 | 1904-06-30 | Louis Emile Albert Durand | Machine agricole dénommée gratteuse-bineuse-sulfateuse, destinée à travailler et sulfater simultanément les vignes ou tous végétaux plantés en rang |
| FR1275E (fr) | 1902-02-21 | 1903-07-01 | Buil Francois Sebastien Joseph | Système de fixation des poignées de vélocipèdes |
| FR2427E (fr) | 1903-08-19 | 1904-04-07 | Paul Steinmetz | Carburateur doseur, pour moteurs à explosion |
| FR5528E (fr) | 1905-03-16 | 1906-05-02 | Farcot Freres Et Cie Soc | Perfectionnements aux turbines à vapeur ou à gaz |
| DE1118403B (de) | 1960-01-27 | 1961-11-30 | Hoechst Ag | Verfahren zur Gewinnung von antitumorwirksamen Sporen |
| FR1275M (fr) | 1961-05-06 | 1962-05-02 | Rene Roger | Médicament a base de colibacilles vivants. |
| BE634858A (enExample) | 1962-07-19 | 1900-01-01 | ||
| FR2828M (fr) | 1963-03-01 | 1964-11-02 | Lucien Nouvel | Médicament renfermant des colibacilles antibiorésistants. |
| FR5528M (enExample) | 1965-10-01 | 1967-11-13 | ||
| GB1271674A (en) | 1968-07-09 | 1972-04-26 | Nisshin Flour Milling Co | Process and preparation for treating diarrhoea in pigs |
| SE371209B (enExample) | 1969-10-13 | 1974-11-11 | Cernelle Ab | |
| DE2134179A1 (de) | 1971-07-09 | 1973-01-25 | Rolf Dr Schuler | Bifidobakterien enthaltendes praeparat und verfahren zur herstellung desselben |
| FR2244464A1 (en) | 1973-06-26 | 1975-04-18 | Serozym Laboratoires | Yeast, lacto- and colibacillus based compsns - used to modify intestinal flora, treat colitis and digestive disorders, etc. |
| US4098728A (en) | 1976-01-02 | 1978-07-04 | Solomon Rosenblatt | Medical surgical sponge and method of making same |
| US4335107A (en) | 1978-06-05 | 1982-06-15 | Snoeyenbos Glenn H | Mixture to protect poultry from salmonella |
| CH637297A5 (fr) | 1978-12-05 | 1983-07-29 | Nestle Sa | Microbille comprenant un microorganisme et son procede de fabrication. |
| US4309782A (en) | 1980-09-11 | 1982-01-12 | Esteban Paulin | Device for collecting fecal specimens |
| US4536409A (en) | 1981-01-23 | 1985-08-20 | American Can Company | Oxygen scavenger |
| US4394377A (en) | 1981-07-31 | 1983-07-19 | Syntex (U.S.A.) Inc. | Ruminant animal performance by co-administering choline and propionate enchancers |
| US4452779A (en) | 1982-02-03 | 1984-06-05 | Cockerill Vernon | Composition and method of treating lactating mammals |
| FI840816A0 (fi) | 1984-03-01 | 1984-03-01 | Farmos Oy | Bakteriepreparat |
| JPS615022A (ja) | 1984-06-19 | 1986-01-10 | Advance Res & Dev Co Ltd | 腸内細菌叢改善剤 |
| US4892731A (en) | 1986-12-11 | 1990-01-09 | Tadashi Arai | Biological intestinal antiseptics |
| IL86859A (en) | 1987-07-10 | 1991-12-15 | E Z Em Inc | Aqueous cathartic solution containing inorganic salts |
| US4948734A (en) | 1987-08-12 | 1990-08-14 | Mycogen Corporation | Novel isolates of bacillus thuringiensis having activity against nematodes |
| US5443826A (en) | 1988-08-02 | 1995-08-22 | Borody; Thomas J. | Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli |
| DE68928665T2 (de) | 1988-08-02 | 1998-11-12 | Gastro Services Pty Ltd | Behandlung von gastro-intestinalen krankheiten |
| US5213807A (en) | 1990-05-03 | 1993-05-25 | Chemburkar Pramod B | Pharmaceutical composition containing ibuprofen and a prostaglandin |
| US5266315A (en) | 1990-05-07 | 1993-11-30 | Kabushiki Kaisha Miyarisan Seibutsu Igaku Kenkyusho | Composite for Clostridium difficile diarrhea and pseudomembranous colitis |
| JP2961184B2 (ja) | 1990-05-07 | 1999-10-12 | ミヤリサン株式会社 | クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物 |
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| JP3047143B2 (ja) | 1992-04-24 | 2000-05-29 | 堀井薬品工業株式会社 | 腸管洗浄液用組成物及び腸管洗浄液 |
| JP3850891B2 (ja) | 1994-03-01 | 2006-11-29 | ゼリア新薬工業株式会社 | 緩下効果を有する組成物 |
| US6984513B2 (en) | 1994-03-03 | 2006-01-10 | The Board Of Trustees Of The Leland Stanford Junior University | Anaerobe targeted enzyme-mediated prodrug therapy |
| JPH07242557A (ja) | 1994-03-03 | 1995-09-19 | Ss Pharmaceut Co Ltd | 乳酸菌含有瀉下薬組成物 |
| CN1094972C (zh) | 1994-05-26 | 2002-11-27 | 伯拉考公司 | 人类来源的乳酸杆菌菌株、它们的组合物及其应用 |
| US5599795A (en) | 1994-08-19 | 1997-02-04 | Mccann; Michael | Method for treatment of idiopathic inflammatory bowel disease (IIBD) |
| AUPM864894A0 (en) | 1994-10-07 | 1994-11-03 | Borody, Thomas Julius | Treatment of bowel-dependent neurological disorders |
| US5800821A (en) | 1995-03-10 | 1998-09-01 | New England Medical Center Hospitals, Inc. | Bacterial spores as a heat stable vaccine delivery system |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US5858356A (en) | 1995-12-21 | 1999-01-12 | Abbott Laboratories | Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals |
| US5902578A (en) | 1996-03-25 | 1999-05-11 | Abbott Laboratories | Method and formula for the prevention of diarrhea |
| US5837238A (en) | 1996-06-05 | 1998-11-17 | Biogaia Biologics Ab | Treatment of diarrhea |
| US6087386A (en) | 1996-06-24 | 2000-07-11 | Merck & Co., Inc. | Composition of enalapril and losartan |
| WO1998013068A1 (fr) | 1996-09-26 | 1998-04-02 | Vladimir Borisovich Kuperman | Medicament prophylactique 'trisan' |
| US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| US6162464A (en) | 1997-03-31 | 2000-12-19 | Inkine Pharmaceutical, Inc. | Non-aqueous colonic purgative formulations |
| US7374753B1 (en) | 1997-06-03 | 2008-05-20 | Ganeden Biotech, Inc. | Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS |
| US6428783B1 (en) | 1998-03-11 | 2002-08-06 | Medtech Center, Inc. | Bank of autochthonous strains of microorganisms and methods of its use for recovery of intestinal microbiocenosis of the men |
| US5902743A (en) | 1998-03-20 | 1999-05-11 | Wisconsin Alumni Research Foundation | Probiotic bifidobacterium strain |
| AU771630B2 (en) | 1998-05-06 | 2004-04-01 | Keijiro Nakamura | Microbial culture liquors containing microorganisms differing in characteristics and living in symbiosis and metabolites thereof, carriers and adsorbents containing the active components of the culture liquors and utilization of the same |
| US6368591B2 (en) | 1998-05-15 | 2002-04-09 | Shanghai Sine Pharmaceutical Corporation Ltd. | Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof |
| AT407008B (de) | 1998-08-06 | 2000-11-27 | Viernstein Helmut Dr | Formulierungen mit probiotisch wirksamen mikroorganismen |
| US6461607B1 (en) | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| AU6049599A (en) | 1998-09-17 | 2000-04-03 | Baxter Healthcare Sa | Streptococcal c beta protein compositions |
| EP1005863A1 (en) | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| CA2354054C (en) | 1998-12-11 | 2011-04-12 | Urex Biotech, Inc. | Oral administration of lactobacillus for the treatment and prevention of urogenital infection |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| ID29150A (id) | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
| EP1163901B1 (en) | 1999-02-26 | 2008-09-10 | Shionogi & Co., Ltd. | Chewable soft capsules having improved administration properties and process for producing the same |
| US20040062757A1 (en) | 2001-06-05 | 2004-04-01 | Finegold Sydney M. | Method of testing gastrointestinal diseases associated with species of genus clostridium |
| US20040170617A1 (en) | 2000-06-05 | 2004-09-02 | Finegold Sydney M. | Method of treating diseases associated with abnormal gastrointestinal flora |
| US20020013270A1 (en) | 2000-06-05 | 2002-01-31 | Bolte Ellen R. | Method for treating a mental disorder |
| US6756032B1 (en) | 2000-07-12 | 2004-06-29 | The Procter & Gamble Company | Method to enhance and/or prolong the effects of a primary challenge to a responsive system with a secondary challenge |
| EP1303285A2 (en) | 2000-07-17 | 2003-04-23 | Chr. Hansen A/S | Methods and formulations with probiotic microorganisms and medicaments |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| US7214370B2 (en) | 2000-12-18 | 2007-05-08 | Probiohealth, Llc | Prebiotic and preservative uses of oil-emulsified probiotic encapsulations |
| US6790453B2 (en) | 2001-03-14 | 2004-09-14 | Mccormick & Company, Inc. | Encapsulation compositions and process for preparing the same |
| US7815956B2 (en) | 2001-04-27 | 2010-10-19 | Pepsico | Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products |
| DK1411900T4 (da) | 2001-06-01 | 2014-01-27 | Pozen Inc | Farmaceutiske sammensætninger til den koordinerede frigørelse af NSAIDs |
| CA2452577C (en) | 2001-07-05 | 2011-04-19 | Wakunaga Pharmaceutical Co., Ltd. | Soft capsules |
| US20030092163A1 (en) | 2001-07-26 | 2003-05-15 | Collins John Kevin | Probiotic bifidobacterium strains |
| US20030092724A1 (en) | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| GB0124580D0 (en) | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
| LT2425821T (lt) | 2002-04-05 | 2017-07-25 | Euro-Celtique S.A. | Farmacinis preparatas, turintis oksikodono ir naloksono |
| CA2391422A1 (en) | 2002-07-12 | 2004-01-12 | David William Molloy | Rifampin (rifadin, rimactone, rifampicin) and doxycycline, (doryx, vibramycin) and the tetracyclines and other compounds currently classified as antibiotics and anti-tuberculous drugs as a treatment to prevent, modify disease progression and/or improve symptoms for neurodegenerative diseases including alzheimers disease, lewy body dementia, schizophrenia,... |
| IL152127A0 (en) | 2002-10-06 | 2003-05-29 | Bio Balance Corp | Probiotic compositions for the treatment of inflammatory bowel disease |
| AU2004265511A1 (en) | 2003-08-18 | 2005-02-24 | The Bio Balance Corporation | A stable liquid probiotic composition, preparation and applications thereof |
| US8192733B2 (en) | 2003-08-29 | 2012-06-05 | Cobb & Associates | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
| US7759105B2 (en) | 2003-08-29 | 2010-07-20 | Cobb & Company, Llp | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
| US20060177424A1 (en) | 2003-08-29 | 2006-08-10 | Cobb Mark L | Treatment of disease states and adverse physiological conditions utilizing anti-fungal compositions |
| US7749509B2 (en) | 2003-08-29 | 2010-07-06 | Cobb And Company, Llp | Treatment of autism using probiotic composition |
| US8016816B2 (en) | 2003-09-09 | 2011-09-13 | Convatec Technologies Inc. | Fecal management appliance and method and apparatus for introducing same |
| US7541091B2 (en) | 2004-05-18 | 2009-06-02 | M & G Usa Corporation | Compartmentalized resin pellets for oxygen scavenging |
| ATE367821T1 (de) | 2004-08-05 | 2007-08-15 | Anidral Srl | Folsäure produzierende bifidobacterium bakterienstämme, ihre formulierungen und verwendung |
| BRPI0418986A (pt) | 2004-08-05 | 2007-12-11 | Anidral Srl | cepas bacterianas bifidobacterium produtoras de ácido fólico, formulações e seus usos |
| US20060076536A1 (en) | 2004-09-29 | 2006-04-13 | Barshied Scott R | Oxygen scavenging pharmaceutical package and methods for making same |
| US20060115465A1 (en) | 2004-10-29 | 2006-06-01 | Macfarlane George | Treatment of gastrointestinal disorders |
| WO2006127355A2 (en) | 2005-05-20 | 2006-11-30 | Dow Global Technologies Inc. | Oral drug compliance monitoring using radio frequency identification tags |
| US20060275223A1 (en) | 2005-06-02 | 2006-12-07 | Burr James B | Erythritol compositions for teeth and gums |
| TWI362949B (en) | 2005-09-13 | 2012-05-01 | Bion Tech Inc | Intestines dissolving nature is able to bear the hydrochloric acid in gastric juice and wrap up the benefit covered and grow the fungus of makes up |
| EP1970055B1 (en) | 2005-12-29 | 2010-11-24 | Osmotica Kereskedelmi És Szolgáltató Kft | Multi-layered tablet with triple release combination |
| JP5006567B2 (ja) | 2006-04-14 | 2012-08-22 | 花王株式会社 | 口腔用固形製剤 |
| US7998510B2 (en) | 2006-08-17 | 2011-08-16 | C. B. Fleet Company, Inc. | Low dose colonic cleansing system |
| JP2008106066A (ja) | 2006-09-25 | 2008-05-08 | Tashiro Yasuaki | サポニン及び生菌を含有する組成物 |
| DE102006062250A1 (de) | 2006-12-22 | 2008-06-26 | Roland Saur-Brosch | Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden |
| PL2136825T3 (pl) | 2007-03-01 | 2014-04-30 | Probi Ab | Zastosowanie bakterii lactobacillus plantarum do zwiększania różnorodności bakteryjnej |
| US8557233B2 (en) | 2007-03-28 | 2013-10-15 | Alimentary Heath Limited | Probiotic bifidobacterium strains |
| NZ580006A (en) | 2007-03-28 | 2012-03-30 | Alimentary Health Ltd | Probiotic bifidobacterium strain 41387 |
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| US20100184785A1 (en) | 2007-06-06 | 2010-07-22 | Basf Se | Pharmaceutical formulation for the production of chewable tablets and lozenges |
| EP2164462B1 (de) | 2007-06-06 | 2017-05-31 | Basf Se | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
| WO2009016133A1 (en) | 2007-07-27 | 2009-02-05 | Cargill, Incorporated | Micronization of polyols |
| EP2030623A1 (en) | 2007-08-17 | 2009-03-04 | Nestec S.A. | Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria |
| US20110008554A1 (en) | 2007-08-31 | 2011-01-13 | Invista North America S.A.R.I. | Oxygen scavenging plastic compositions |
| US20100233278A1 (en) | 2007-09-27 | 2010-09-16 | Akiko Ookawa | Rapidly disintegrating solid preparation |
| EP2572705B1 (en) | 2007-10-01 | 2017-09-13 | Laboratorios Lesvi, S.L. | Orodispersible tablets |
| WO2009052391A1 (en) | 2007-10-19 | 2009-04-23 | Purdue Research Foundation | Solid formulations of crystalline compounds |
| EP2203551B1 (en) | 2007-10-20 | 2013-08-21 | Université de Liège | Bifidobacterial species |
| ES2473625T3 (es) | 2007-10-26 | 2014-07-07 | Brenda E. Moore | Composición probi�tica y métodos para inducir y mantener la pérdida de peso |
| JP5258268B2 (ja) | 2007-11-19 | 2013-08-07 | フロイント産業株式会社 | 球形粒の製造方法 |
| EP2233129B1 (en) | 2007-12-28 | 2014-05-07 | Sawai Pharmaceutical Co., Ltd. | Oral cavity disintegrating tablet and method of producing the same |
| BRPI0920465A2 (pt) | 2008-10-02 | 2018-03-20 | Salix Pharmaceuticals, Inc. | metodo de tratamento de encefalopatia hepática |
| US20100178413A1 (en) | 2008-12-17 | 2010-07-15 | Mark Gorris | Food-based Supplement Delivery System |
| WO2010103132A1 (es) | 2009-03-10 | 2010-09-16 | Hero España, S.A. | Aislamiento, identificación y caracterización de cepas con actividad probiótica a partir de heces de lactantes alimentados exclusivamente con leche materna |
| US20100255231A1 (en) | 2009-04-01 | 2010-10-07 | Multisorb Technologies, Inc. | Oxygen scavenging films |
| ES2425385T3 (es) | 2009-04-30 | 2013-10-15 | Actogenix N.V. | Crioprotectores para la liofilización de las bacterias de ácido láctico |
| US20100285164A1 (en) | 2009-05-11 | 2010-11-11 | Jrs Pharma | Orally Disintegrating Excipient |
| US20120064133A1 (en) | 2009-05-28 | 2012-03-15 | Ishwar Chauhan | Multiparticulate Controlled-Release Selective Serotonin Reuptake Inhibitor Formulations |
| CN201441672U (zh) | 2009-07-14 | 2010-04-28 | 赵伟华 | 一次性灌肠装置 |
| US20110045222A1 (en) | 2009-08-19 | 2011-02-24 | Eastman Chemical Company | Oxygen-scavenging polymer blends suitable for use in packaging |
| GB0916335D0 (en) | 2009-09-17 | 2009-10-28 | Martin W J | Medicaments |
| US20110081320A1 (en) | 2009-10-06 | 2011-04-07 | Nubiome, Inc. | Treatment/Cure of Autoimmune Disease |
| US20120276149A1 (en) | 2009-10-15 | 2012-11-01 | Dan Littman | Methods for modulating bacterial infection |
| US20110218216A1 (en) | 2010-01-29 | 2011-09-08 | Kumaravel Vivek | Extended release pharmaceutical composition of donepezil |
| EP4663746A3 (en) | 2010-02-01 | 2026-04-15 | Ferring Microbiome Inc. | Bacteriotherapy for clostridium difficile colitis |
| US7888062B1 (en) | 2010-02-01 | 2011-02-15 | Microbios, Inc. | Process and composition for the manufacture of a microbial-based product |
| US8853269B2 (en) | 2010-02-04 | 2014-10-07 | Copperhead Chemical Company Inc. | Composition and method for treating infections and promoting intestinal health |
| US20130121916A1 (en) | 2010-03-10 | 2013-05-16 | Sergio Baroni | Compositions for Colon Lavage and Methods of Making and Using Same |
| US9707207B2 (en) | 2010-05-26 | 2017-07-18 | The United States Of America As Represented By The Department Of Veterans Affairs | Method for diagnosing, preventing, and treating neurological diseases |
| WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
| CA2807242C (en) | 2010-08-04 | 2017-05-02 | Thomas Julius Borody | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| EP2646567A4 (en) | 2010-10-04 | 2014-03-26 | British Columbia Cancer Agency | DETECTION OF FUSOBACTERIUM IN A GASTROINTESTINAL SAMPLE FOR THE DIAGNOSIS OF GASTROINTESTINAL CARCINOMA |
| WO2012048152A2 (en) | 2010-10-07 | 2012-04-12 | Mazmanian Sarkis K | Probiotic therapies for autism |
| US20150374761A1 (en) | 2011-03-09 | 2015-12-31 | Regents Of The University Of Minnesota | Freeze dried fecal microbiota for use in fecal microbial transplantation |
| WO2014152484A1 (en) * | 2013-03-14 | 2014-09-25 | Regents Of The University Of Minnesota | Freeze dried fecal microbiota for use in fecal microbial transplantation |
| BR112013022927A2 (pt) * | 2011-03-09 | 2016-12-06 | Univ Minnesota | composição, métodos para substituir ou suplementar ou modificar uma microbiota do cólon de um sujeito, e para tratar um sujeito, e, uso de uma composição |
| EP2756071B1 (en) | 2011-09-14 | 2017-12-20 | University Of Guelph | Media supplements and methods to culture human gastrointestinal anaerobic microorganisms |
| DK2750682T3 (en) | 2011-10-11 | 2016-08-22 | Achim Biotherapeutics Ab | A composition comprising anaerobically cultured human intestinal flora |
| CA2892588A1 (en) | 2011-12-01 | 2013-06-06 | School Corporation, Azabu Veterinary Medicine Educational Institution | Human-derived bacteria that induce proliferation or accumulation of regulatory t cells |
| WO2013090825A1 (en) | 2011-12-15 | 2013-06-20 | Pureflora, Inc. | Device for the collection, refinement, and administration of gastrointestinal microflora |
| JP6285915B2 (ja) | 2012-05-02 | 2018-02-28 | チャールズ リバー ラボラトリーズ, インコーポレイテッド | 生死判別染色法 |
| US9719144B2 (en) | 2012-05-25 | 2017-08-01 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| CN114949001A (zh) | 2012-08-29 | 2022-08-30 | 加州理工学院 | 孤独症谱系障碍的诊断和治疗 |
| MX2015006491A (es) | 2012-11-23 | 2015-12-03 | Seres Health Inc | Composiciones bacterianas sinergicas y metodos de produccion y uso de las mismas. |
| CN104918624A (zh) * | 2012-11-26 | 2015-09-16 | 托马斯·朱利叶斯·波洛迪 | 恢复排泄物微生物群的组合物及其制造和使用方法 |
| MX369877B (es) | 2013-02-04 | 2019-11-25 | Seres Therapeutics Inc | Composiciones y metodos. |
| US9907755B2 (en) | 2013-03-14 | 2018-03-06 | Therabiome, Llc | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
| EP2991649B1 (en) | 2013-04-30 | 2020-06-03 | Thomas Julius Borody | Compositions for treating obsessive-compulsive disorder |
| US9511100B2 (en) | 2013-06-05 | 2016-12-06 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9511099B2 (en) | 2013-06-05 | 2016-12-06 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9782445B2 (en) | 2013-06-05 | 2017-10-10 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9764019B2 (en) | 2013-07-09 | 2017-09-19 | Vedanta Biosciences, Inc. | Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease |
| AU2014331610B2 (en) | 2013-10-03 | 2019-11-07 | Trustees Of The University Of Pennsylvania | Compositions comprising a defined microbiome and methods of use thereof |
| MX367109B (es) | 2013-11-25 | 2019-08-05 | Seres Therapeutics Inc | Composiciones bacterianas sinergicas y sus metodos de produccion y usos. |
| US9956282B2 (en) | 2013-12-16 | 2018-05-01 | Seres Therapeutics, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
| CN114159476A (zh) | 2015-05-14 | 2022-03-11 | 克雷斯顿沃控股公司 | 用于粪便菌群移植的组合物以及用于制备和使用它们的方法和用于递送它们的装置 |
| CN114366759A (zh) | 2015-05-22 | 2022-04-19 | 亚利桑那大学董事会 | 用于治疗自闭症谱系障碍及相关症状的方法 |
| EP3368050A1 (en) | 2015-10-26 | 2018-09-05 | Crestovo Holdings LLC | Compositions and methods for fecal microbiota-related therapy |
| CN115919906A (zh) | 2016-03-04 | 2023-04-07 | 加利福尼亚大学董事会 | 微生物聚生体及其用途 |
| US20180036352A1 (en) * | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
-
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- 2017-10-24 US US15/791,868 patent/US10195235B2/en active Active
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004501095A (ja) | 2000-05-11 | 2004-01-15 | アンスティテュ ナショナール ド ラ ルシェルシュ アグロノミク | 消化器系障害の予防または治療のための水素依存性酢酸生成株の使用 |
| JP2016521704A (ja) | 2013-06-05 | 2016-07-25 | レビオティクス インコーポレイテッドRebiotix,Inc. | 微生物叢回復療法(mrt)、組成物および製造方法 |
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| AU2017306303A1 (en) | 2019-02-14 |
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| US20190175665A1 (en) | 2019-06-13 |
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