JP7433051B2 - Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 - Google Patents
Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 Download PDFInfo
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- JP7433051B2 JP7433051B2 JP2019571410A JP2019571410A JP7433051B2 JP 7433051 B2 JP7433051 B2 JP 7433051B2 JP 2019571410 A JP2019571410 A JP 2019571410A JP 2019571410 A JP2019571410 A JP 2019571410A JP 7433051 B2 JP7433051 B2 JP 7433051B2
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K38/19—Cytokines; Lymphokines; Interferons
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- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- C07K14/76—Albumins
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- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- C12N5/0634—Cells from the blood or the immune system
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023211159A JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762521957P | 2017-06-19 | 2017-06-19 | |
| US62/521,957 | 2017-06-19 | ||
| US201862679687P | 2018-06-01 | 2018-06-01 | |
| US62/679,687 | 2018-06-01 | ||
| PCT/IB2018/000760 WO2018234862A1 (en) | 2017-06-19 | 2018-06-19 | Uses and methods for il-2 superagonists, agonists, and fusions thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023211159A Division JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020524174A JP2020524174A (ja) | 2020-08-13 |
| JP2020524174A5 JP2020524174A5 (enExample) | 2021-07-29 |
| JP7433051B2 true JP7433051B2 (ja) | 2024-02-19 |
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ID=64737001
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571410A Active JP7433051B2 (ja) | 2017-06-19 | 2018-06-19 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
| JP2023211159A Active JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023211159A Active JP7747716B2 (ja) | 2017-06-19 | 2023-12-14 | Il-2スーパーアゴニスト、アゴニスト、およびそれらの融合体の使用および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11542312B2 (enExample) |
| EP (1) | EP3641814A4 (enExample) |
| JP (2) | JP7433051B2 (enExample) |
| CN (1) | CN111201035A (enExample) |
| AU (2) | AU2018287317B2 (enExample) |
| CA (1) | CA3067909A1 (enExample) |
| WO (1) | WO2018234862A1 (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| CA2946398A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| CN117384961A (zh) | 2016-02-23 | 2024-01-12 | 萨克生物研究学院 | 对病毒动力学影响最小的治疗性腺病毒中的外源基因表达 |
| AU2017222568B2 (en) | 2016-02-23 | 2020-09-10 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| CA3056630A1 (en) | 2017-03-15 | 2018-09-20 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
| CA3064435A1 (en) | 2017-05-24 | 2018-11-29 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
| CN111201035A (zh) | 2017-06-19 | 2020-05-26 | 梅迪塞纳医疗股份有限公司 | Il-2超激动剂、激动剂及其融合体的用途和方法 |
| EP3713592A4 (en) | 2017-11-21 | 2022-01-12 | The Board of Trustees of the Leland Stanford Junior University | INTERLEUKIN-2 PARTIAL AGONISTS |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| AU2019322487B2 (en) * | 2018-03-19 | 2024-04-18 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer |
| MX2020010499A (es) | 2018-04-09 | 2020-10-28 | Salk Inst For Biological Studi | Composiciones de adenovirus oncoliticas con propiedades aumentadas de replicacion. |
| KR20210038549A (ko) * | 2018-07-24 | 2021-04-07 | 비온테크 알엔에이 파마슈티컬스 게엠베하 | Il2 작용제 |
| HRP20240825T1 (hr) | 2018-11-14 | 2024-09-27 | Regeneron Pharmaceuticals, Inc. | Intralezijsko davanje pd-1 inhibitora za liječenje raka kože |
| AR117770A1 (es) * | 2019-01-07 | 2021-08-25 | Inhibrx Inc | Polipéptidos que comprenden polipéptidos con il-2 modificada y usos de los mismos |
| US11529402B2 (en) | 2019-01-14 | 2022-12-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
| AU2020228296B2 (en) * | 2019-02-28 | 2025-10-02 | Regeneron Pharmaceuticals, Inc. | Administration of PD-1 inhibitors for treating skin cancer |
| CN118388628A (zh) * | 2019-03-29 | 2024-07-26 | 居里研究所 | 具有经修饰的生物活性的白介素-2变体 |
| BR112021023345A2 (pt) | 2019-05-20 | 2022-02-01 | Pandion Operations Inc | Imunotolerância com alvo em madcam |
| CA3142738A1 (en) * | 2019-06-05 | 2020-12-10 | Asher Biotherapeutics, Inc. | Fusions of mutant interleukin-2 polypeptides with antigen binding molecules for modulating immune cell function |
| CN110256583B (zh) * | 2019-07-11 | 2022-05-20 | 中国科学院生物物理研究所 | 一种il-2突变体与抗体的融合蛋白及其应用 |
| EP4013777A4 (en) * | 2019-08-15 | 2024-01-17 | Cytimm Therapeutics, Inc. | MODIFIED INTERLEUKIN 2 (IL-2) POLYPEPTIDES, CONJUGATES AND USES THEREOF |
| EP4031582A4 (en) * | 2019-09-18 | 2023-10-04 | The Regents of the University of California | IMMUNOACTIVE MICROPARTICLES AND ASSOCIATED USES |
| WO2021055660A1 (en) * | 2019-09-18 | 2021-03-25 | The Regents Of The University Of California | Protein producing nanoliposomes and uses thereof |
| US20220403026A1 (en) * | 2019-09-18 | 2022-12-22 | The Regents Of The University Of California | Implantable scaffolds and uses thereof for immunotherapy and other uses |
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