JP7430877B2 - 造血前駆細胞マーカー - Google Patents

造血前駆細胞マーカー Download PDF

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Publication number
JP7430877B2
JP7430877B2 JP2019514588A JP2019514588A JP7430877B2 JP 7430877 B2 JP7430877 B2 JP 7430877B2 JP 2019514588 A JP2019514588 A JP 2019514588A JP 2019514588 A JP2019514588 A JP 2019514588A JP 7430877 B2 JP7430877 B2 JP 7430877B2
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cells
positive
fraction
negative
hematopoietic progenitor
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Japanese (ja)
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JPWO2018199186A1 (ja
Inventor
新 金子
翔一 入口
雄太 三嶋
義明 葛西
哲 林
寿来留 有馬
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Takeda Pharmaceutical Co Ltd
Kyoto University NUC
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Takeda Pharmaceutical Co Ltd
Kyoto University NUC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/505—CD4; CD8
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019514588A 2017-04-26 2018-04-25 造血前駆細胞マーカー Active JP7430877B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023139109A JP7610817B2 (ja) 2017-04-26 2023-08-29 造血前駆細胞マーカー

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017087723 2017-04-26
JP2017087723 2017-04-26
PCT/JP2018/016864 WO2018199186A1 (ja) 2017-04-26 2018-04-25 造血前駆細胞マーカー

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023139109A Division JP7610817B2 (ja) 2017-04-26 2023-08-29 造血前駆細胞マーカー

Publications (2)

Publication Number Publication Date
JPWO2018199186A1 JPWO2018199186A1 (ja) 2020-05-14
JP7430877B2 true JP7430877B2 (ja) 2024-02-14

Family

ID=63918584

Family Applications (2)

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JP2019514588A Active JP7430877B2 (ja) 2017-04-26 2018-04-25 造血前駆細胞マーカー
JP2023139109A Active JP7610817B2 (ja) 2017-04-26 2023-08-29 造血前駆細胞マーカー

Family Applications After (1)

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JP2023139109A Active JP7610817B2 (ja) 2017-04-26 2023-08-29 造血前駆細胞マーカー

Country Status (13)

Country Link
US (1) US20210102167A1 (https=)
EP (1) EP3617307A4 (https=)
JP (2) JP7430877B2 (https=)
KR (1) KR102803233B1 (https=)
CN (1) CN110691843B (https=)
AU (1) AU2018257307B2 (https=)
BR (1) BR112019022288A2 (https=)
CA (1) CA3061289A1 (https=)
EA (1) EA201992483A1 (https=)
IL (1) IL270126B2 (https=)
SG (1) SG11201909795RA (https=)
TW (1) TWI860972B (https=)
WO (1) WO2018199186A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250230411A1 (en) 2022-03-23 2025-07-17 Kyoto University Method for producing regulatory t cells
WO2023247722A1 (en) * 2022-06-22 2023-12-28 Fondazione Telethon Ets Method for isolating hemogenic endothelial cells
JPWO2024071010A1 (https=) 2022-09-26 2024-04-04
WO2024152926A1 (zh) * 2023-01-18 2024-07-25 深圳市人民医院 造血祖细胞的谱系及其命运决定基因的鉴定及应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070072295A1 (en) 2005-06-01 2007-03-29 Slukvin Igor I Multipotent lymphohematopoietic progenitor cells
WO2011041912A1 (en) 2009-10-09 2011-04-14 University Health Network Self-renewing single human hematopoietic stem cells, an early lymphoid progenitor and methods of enriching the same
JP2014533494A (ja) 2011-11-21 2014-12-15 ユニバーシティ・ヘルス・ネットワーク 造血前駆体の集団および造血前駆体のための幹細胞を富化する方法
WO2016076415A1 (ja) 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015163185A1 (ja) * 2014-04-24 2015-10-29 学校法人関西医科大学 ヒト造血幹細胞濃縮画分の製造方法
WO2016168586A1 (en) * 2015-04-16 2016-10-20 The Board Of Regents, The University Of Texas System Cd133+ cells and method for expanding
US10961308B2 (en) * 2015-06-29 2021-03-30 The General Hospital Corporation Embigin inhibition for promotion of hematopoietic stem and progenitor cell expansion
CA3003152A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
US10350873B2 (en) 2015-11-11 2019-07-16 Xerox Corporation System and method for removing support structure from three-dimensional printed objects using microwave energy and nanoparticles
EP3476934A4 (en) 2016-06-23 2020-02-26 Kyoto University METHOD FOR PRODUCING CD4 / CD8 POSITIVE DUAL T CELLS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070072295A1 (en) 2005-06-01 2007-03-29 Slukvin Igor I Multipotent lymphohematopoietic progenitor cells
WO2011041912A1 (en) 2009-10-09 2011-04-14 University Health Network Self-renewing single human hematopoietic stem cells, an early lymphoid progenitor and methods of enriching the same
JP2014533494A (ja) 2011-11-21 2014-12-15 ユニバーシティ・ヘルス・ネットワーク 造血前駆体の集団および造血前駆体のための幹細胞を富化する方法
WO2016076415A1 (ja) 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TIMMERMANS, F et al.，Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones，The Journal of Immunology，2009年05月19日，Vol. 182, No. 11，pp. 6879-6888, DATA SUPPLEMENT

Also Published As

Publication number Publication date
CN110691843B (zh) 2023-10-20
BR112019022288A2 (pt) 2020-05-19
SG11201909795RA (en) 2019-11-28
KR102803233B1 (ko) 2025-05-07
JP2023164892A (ja) 2023-11-14
JP7610817B2 (ja) 2025-01-09
WO2018199186A1 (ja) 2018-11-01
US20210102167A1 (en) 2021-04-08
IL270126A (en) 2019-12-31
NZ758956A (en) 2024-11-29
EP3617307A1 (en) 2020-03-04
TWI860972B (zh) 2024-11-11
TW201843301A (zh) 2018-12-16
IL270126B1 (en) 2024-12-01
EA201992483A1 (ru) 2020-03-06
AU2018257307A1 (en) 2019-11-21
CN110691843A (zh) 2020-01-14
JPWO2018199186A1 (ja) 2020-05-14
AU2018257307B2 (en) 2024-11-07
EP3617307A4 (en) 2021-01-27
IL270126B2 (en) 2025-04-01
CA3061289A1 (en) 2019-10-23
KR20200002909A (ko) 2020-01-08

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