IL270126B2 - Hematopoietic stem cell marker - Google Patents

Hematopoietic stem cell marker

Info

Publication number
IL270126B2
IL270126B2 IL270126A IL27012619A IL270126B2 IL 270126 B2 IL270126 B2 IL 270126B2 IL 270126 A IL270126 A IL 270126A IL 27012619 A IL27012619 A IL 27012619A IL 270126 B2 IL270126 B2 IL 270126B2
Authority
IL
Israel
Prior art keywords
positive
cells
antibody
fraction
cell
Prior art date
Application number
IL270126A
Other languages
English (en)
Hebrew (he)
Other versions
IL270126A (en
IL270126B1 (en
Original Assignee
Univ Kyoto
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyoto, Takeda Pharmaceuticals Co filed Critical Univ Kyoto
Publication of IL270126A publication Critical patent/IL270126A/en
Publication of IL270126B1 publication Critical patent/IL270126B1/en
Publication of IL270126B2 publication Critical patent/IL270126B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/505—CD4; CD8
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL270126A 2017-04-26 2018-04-25 Hematopoietic stem cell marker IL270126B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017087723 2017-04-26
PCT/JP2018/016864 WO2018199186A1 (ja) 2017-04-26 2018-04-25 造血前駆細胞マーカー

Publications (3)

Publication Number Publication Date
IL270126A IL270126A (en) 2019-12-31
IL270126B1 IL270126B1 (en) 2024-12-01
IL270126B2 true IL270126B2 (en) 2025-04-01

Family

ID=63918584

Family Applications (1)

Application Number Title Priority Date Filing Date
IL270126A IL270126B2 (en) 2017-04-26 2018-04-25 Hematopoietic stem cell marker

Country Status (13)

Country Link
US (1) US20210102167A1 (https=)
EP (1) EP3617307A4 (https=)
JP (2) JP7430877B2 (https=)
KR (1) KR102803233B1 (https=)
CN (1) CN110691843B (https=)
AU (1) AU2018257307B2 (https=)
BR (1) BR112019022288A2 (https=)
CA (1) CA3061289A1 (https=)
EA (1) EA201992483A1 (https=)
IL (1) IL270126B2 (https=)
SG (1) SG11201909795RA (https=)
TW (1) TWI860972B (https=)
WO (1) WO2018199186A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250230411A1 (en) 2022-03-23 2025-07-17 Kyoto University Method for producing regulatory t cells
WO2023247722A1 (en) * 2022-06-22 2023-12-28 Fondazione Telethon Ets Method for isolating hemogenic endothelial cells
JPWO2024071010A1 (https=) 2022-09-26 2024-04-04
WO2024152926A1 (zh) * 2023-01-18 2024-07-25 深圳市人民医院 造血祖细胞的谱系及其命运决定基因的鉴定及应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014533494A (ja) * 2011-11-21 2014-12-15 ユニバーシティ・ヘルス・ネットワーク 造血前駆体の集団および造血前駆体のための幹細胞を富化する方法
WO2015163185A1 (ja) * 2014-04-24 2015-10-29 学校法人関西医科大学 ヒト造血幹細胞濃縮画分の製造方法
WO2016076415A1 (ja) * 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法
WO2017078807A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034613B2 (en) 2005-06-01 2011-10-11 Wisconsin Alumni Research Foundation Multipotent lymphohematopoietic progenitor cells
WO2011041912A1 (en) 2009-10-09 2011-04-14 University Health Network Self-renewing single human hematopoietic stem cells, an early lymphoid progenitor and methods of enriching the same
WO2016168586A1 (en) * 2015-04-16 2016-10-20 The Board Of Regents, The University Of Texas System Cd133+ cells and method for expanding
US10961308B2 (en) * 2015-06-29 2021-03-30 The General Hospital Corporation Embigin inhibition for promotion of hematopoietic stem and progenitor cell expansion
US10350873B2 (en) 2015-11-11 2019-07-16 Xerox Corporation System and method for removing support structure from three-dimensional printed objects using microwave energy and nanoparticles
EP3476934A4 (en) 2016-06-23 2020-02-26 Kyoto University METHOD FOR PRODUCING CD4 / CD8 POSITIVE DUAL T CELLS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014533494A (ja) * 2011-11-21 2014-12-15 ユニバーシティ・ヘルス・ネットワーク 造血前駆体の集団および造血前駆体のための幹細胞を富化する方法
WO2015163185A1 (ja) * 2014-04-24 2015-10-29 学校法人関西医科大学 ヒト造血幹細胞濃縮画分の製造方法
WO2016076415A1 (ja) * 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法
WO2017078807A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHRISTINA GIESE-RT ET AL:, THE MONOCLONAL ANTIBODY W7C5 DEFINES ANOVEL SURFACE ANTIGEN ON HEMATOPOIETIC STEM CELLS, 1 June 2001 (2001-06-01) *
TIMMERMANS, F. ET AL.,, GENERATION OF T CELLS FROM HUMAN EMBRYONIC STEM CELL -DERIVED HEMATOPOIETIC ZONES, 19 May 2009 (2009-05-19) *
UNIV HEALTH NETWORK [CA], WO2011041912, 14 April 2011 (2011-04-14) *
VODYANIK, MAXIM A., JAMES A. THOMSON, AND IGOR I. SLUKVIN., CD43 DEFINES EARLY HEMATOPOIETIC PROGENITORS DERIVED FROM HUMAN EMBRYONIC STEM CELLS (HESC)., 31 December 2004 (2004-12-31) *
YU, QING, ET AL., IN VITRO EVIDENCE THAT CYTOKINE RECEPTOR SIGNALS ARE REQUIRED FOR DIFFERENTIATION OF DOUBLE POSITIVE THYMOCYTES INTO FUNCTIONALLY MATURE CD8+ T CELLS., 17 February 2003 (2003-02-17) *

Also Published As

Publication number Publication date
CN110691843B (zh) 2023-10-20
BR112019022288A2 (pt) 2020-05-19
SG11201909795RA (en) 2019-11-28
KR102803233B1 (ko) 2025-05-07
JP2023164892A (ja) 2023-11-14
JP7610817B2 (ja) 2025-01-09
WO2018199186A1 (ja) 2018-11-01
US20210102167A1 (en) 2021-04-08
IL270126A (en) 2019-12-31
NZ758956A (en) 2024-11-29
EP3617307A1 (en) 2020-03-04
TWI860972B (zh) 2024-11-11
TW201843301A (zh) 2018-12-16
IL270126B1 (en) 2024-12-01
EA201992483A1 (ru) 2020-03-06
AU2018257307A1 (en) 2019-11-21
CN110691843A (zh) 2020-01-14
JPWO2018199186A1 (ja) 2020-05-14
AU2018257307B2 (en) 2024-11-07
EP3617307A4 (en) 2021-01-27
CA3061289A1 (en) 2019-10-23
JP7430877B2 (ja) 2024-02-14
KR20200002909A (ko) 2020-01-08

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