TWI860972B - 造血前驅細胞標記 - Google Patents

造血前驅細胞標記 Download PDF

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Publication number
TWI860972B
TWI860972B TW107114033A TW107114033A TWI860972B TW I860972 B TWI860972 B TW I860972B TW 107114033 A TW107114033 A TW 107114033A TW 107114033 A TW107114033 A TW 107114033A TW I860972 B TWI860972 B TW I860972B
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TW
Taiwan
Prior art keywords
cells
positive
negative
cell
hematopoietic progenitor
Prior art date
Application number
TW107114033A
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English (en)
Chinese (zh)
Other versions
TW201843301A (zh
Inventor
金子新
入口翔一
三嶋雄太
葛西義明
林哲
有馬寿来留
Original Assignee
國立大學法人京都大學
日商武田藥品工業股份有限公司
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Application filed by 國立大學法人京都大學, 日商武田藥品工業股份有限公司 filed Critical 國立大學法人京都大學
Publication of TW201843301A publication Critical patent/TW201843301A/zh
Application granted granted Critical
Publication of TWI860972B publication Critical patent/TWI860972B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/505—CD4; CD8
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
TW107114033A 2017-04-26 2018-04-25 造血前驅細胞標記 TWI860972B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017-087723 2017-04-26
JP2017087723 2017-04-26

Publications (2)

Publication Number Publication Date
TW201843301A TW201843301A (zh) 2018-12-16
TWI860972B true TWI860972B (zh) 2024-11-11

Family

ID=63918584

Family Applications (1)

Application Number Title Priority Date Filing Date
TW107114033A TWI860972B (zh) 2017-04-26 2018-04-25 造血前驅細胞標記

Country Status (13)

Country Link
US (1) US20210102167A1 (https=)
EP (1) EP3617307A4 (https=)
JP (2) JP7430877B2 (https=)
KR (1) KR102803233B1 (https=)
CN (1) CN110691843B (https=)
AU (1) AU2018257307B2 (https=)
BR (1) BR112019022288A2 (https=)
CA (1) CA3061289A1 (https=)
EA (1) EA201992483A1 (https=)
IL (1) IL270126B2 (https=)
SG (1) SG11201909795RA (https=)
TW (1) TWI860972B (https=)
WO (1) WO2018199186A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119256076A (zh) 2022-03-23 2025-01-03 国立大学法人京都大学 用于产生调节性t细胞的方法
WO2023247722A1 (en) * 2022-06-22 2023-12-28 Fondazione Telethon Ets Method for isolating hemogenic endothelial cells
EP4600352A1 (en) 2022-09-26 2025-08-13 Kyoto University T cell production method
CN118613579A (zh) * 2023-01-18 2024-09-06 深圳市人民医院 造血祖细胞的谱系及其命运决定基因的鉴定及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011041912A1 (en) * 2009-10-09 2011-04-14 University Health Network Self-renewing single human hematopoietic stem cells, an early lymphoid progenitor and methods of enriching the same
WO2016076415A1 (ja) * 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034613B2 (en) * 2005-06-01 2011-10-11 Wisconsin Alumni Research Foundation Multipotent lymphohematopoietic progenitor cells
SG11201402502RA (en) * 2011-11-21 2015-01-29 Sunnybrook Res Inst Populations of hematopoietic progenitors and methods of enriching stem cells therefor
WO2015163185A1 (ja) * 2014-04-24 2015-10-29 学校法人関西医科大学 ヒト造血幹細胞濃縮画分の製造方法
US10590387B2 (en) * 2015-04-16 2020-03-17 The Board Of Regents Of The University Of Texas System CD133+ cells and method for expanding
WO2017004127A1 (en) * 2015-06-29 2017-01-05 The General Hospital Corporation Embigin inhibition for promotion of hematopoietic stem and progenitor cell expansion
SG11201803145RA (en) * 2015-11-04 2018-05-30 Fate Therapeutics Inc Methods and compositions for inducing hematopoietic cell differentiation
US10350873B2 (en) 2015-11-11 2019-07-16 Xerox Corporation System and method for removing support structure from three-dimensional printed objects using microwave energy and nanoparticles
US11578310B2 (en) 2016-06-23 2023-02-14 Kyoto University Method for producing CD4/CD8 double-positive T cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011041912A1 (en) * 2009-10-09 2011-04-14 University Health Network Self-renewing single human hematopoietic stem cells, an early lymphoid progenitor and methods of enriching the same
WO2016076415A1 (ja) * 2014-11-13 2016-05-19 国立大学法人京都大学 多能性幹細胞からｔ細胞への誘導方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
期刊 Timmermans, Frank, et al. "Generation of T cells from human embryonic stem cell-derived hematopoietic zones." The Journal of Immunology, Vol.182, No.11, American Association of Immunologists, 2009, page 6879-6888 *

Also Published As

Publication number Publication date
BR112019022288A2 (pt) 2020-05-19
CA3061289A1 (en) 2019-10-23
CN110691843A (zh) 2020-01-14
EP3617307A4 (en) 2021-01-27
JP7430877B2 (ja) 2024-02-14
TW201843301A (zh) 2018-12-16
SG11201909795RA (en) 2019-11-28
NZ758956A (en) 2024-11-29
EP3617307A1 (en) 2020-03-04
IL270126B1 (en) 2024-12-01
EA201992483A1 (ru) 2020-03-06
AU2018257307B2 (en) 2024-11-07
JP2023164892A (ja) 2023-11-14
AU2018257307A1 (en) 2019-11-21
CN110691843B (zh) 2023-10-20
IL270126A (en) 2019-12-31
WO2018199186A1 (ja) 2018-11-01
JPWO2018199186A1 (ja) 2020-05-14
KR20200002909A (ko) 2020-01-08
US20210102167A1 (en) 2021-04-08
JP7610817B2 (ja) 2025-01-09
IL270126B2 (en) 2025-04-01
KR102803233B1 (ko) 2025-05-07

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