JP7386798B2 - 固定中の筋力低下の防止に使用する植物エクジソン - Google Patents

固定中の筋力低下の防止に使用する植物エクジソン Download PDF

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JP7386798B2
JP7386798B2 JP2020545181A JP2020545181A JP7386798B2 JP 7386798 B2 JP7386798 B2 JP 7386798B2 JP 2020545181 A JP2020545181 A JP 2020545181A JP 2020545181 A JP2020545181 A JP 2020545181A JP 7386798 B2 JP7386798 B2 JP 7386798B2
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muscle
immobilization
group
days
alkylene
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JPWO2019166717A5 (https=
JP2021516228A5 (https=
JP2021516228A (ja
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ディルダ，ピエール
ラティル，マチルド
ラフォン，ルネ
ヴェイエ，スタニスラス
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Sorbonne Universite
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Sorbonne Universite
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020545181A 2018-02-28 2019-02-20 固定中の筋力低下の防止に使用する植物エクジソン Active JP7386798B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1851778 2018-02-28
FR1851778A FR3078252B1 (fr) 2018-02-28 2018-02-28 Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
PCT/FR2019/050392 WO2019166717A1 (fr) 2018-02-28 2019-02-20 Phytoecdysones pour leur utilisation dans la prévention de la perte de force musculaire lors d'une immobilisation

Publications (4)

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JP2021516228A JP2021516228A (ja) 2021-07-01
JPWO2019166717A5 JPWO2019166717A5 (https=) 2022-02-09
JP2021516228A5 JP2021516228A5 (https=) 2022-02-09
JP7386798B2 true JP7386798B2 (ja) 2023-11-27

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JP2020545181A Active JP7386798B2 (ja) 2018-02-28 2019-02-20 固定中の筋力低下の防止に使用する植物エクジソン

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US (2) US20210369735A1 (https=)
EP (1) EP3758709B1 (https=)
JP (1) JP7386798B2 (https=)
KR (1) KR20200128058A (https=)
CN (1) CN111954534A (https=)
BR (1) BR112020017492A2 (https=)
ES (1) ES3039265T3 (https=)
FR (1) FR3078252B1 (https=)
WO (1) WO2019166717A1 (https=)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150099022A1 (en) 2011-12-13 2015-04-09 Institut Biophytis Sas Phytoecdysones for use in improving the muscle quality of obese and/or sarcopenic mammals
WO2015151066A1 (en) 2014-04-04 2015-10-08 Polifenoles Naturales, S.L. Treatment of sarcopenia with ecdysteroids
US20160220624A1 (en) 2015-02-03 2016-08-04 Naturex Sa Compositions and Methods for Improved Muscle Metabolism
WO2016166480A1 (fr) 2015-04-16 2016-10-20 Metabrain Research Dérives utiles dans le traitement de l'atrophie musculaire
JP2017516851A (ja) 2014-05-20 2017-06-22 ビオフィティス 化合物及び筋肉の質を改善するためのその使用
JP2020517697A (ja) 2017-04-28 2020-06-18 ビオフィティス 医薬品グレードの２０−ヒドロキシエクジソン抽出物、その使用、およびその調製

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH684572A5 (fr) * 1992-04-16 1994-10-31 Jean Louis Connat Nourriture à base d'ecdystéroîdes abaissant la fertilité des parasites hématophages.
AU2003902621A0 (en) * 2003-05-27 2003-06-12 Commonwealth Scientific And Industrial Research Organisation Ecdysone receiptor ligand-binding domain structure
FR2924346B1 (fr) * 2007-11-30 2010-02-19 Inst Biophytis Sas Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique.
EP2265116A4 (en) * 2008-03-14 2013-02-06 Intrexon Corp STEROID LIGANDS AND THEIR USE IN GENE SWITCH MODULATION
RU2390270C1 (ru) * 2009-03-13 2010-05-27 Общество С Ограниченной Ответственностью "Парафарм" Биологически активная добавка к пище
WO2010132982A1 (en) * 2009-05-18 2010-11-25 Ottawa Hospital Research Institute Treatment of muscle disease characterized by insulin resistance
AU2011343970A1 (en) * 2010-12-13 2013-07-04 Rutgers University Methods of producing and using brassinosteroids to promote growth, repair and maintenance of skeletal muscle and skin
FR2982489B1 (fr) * 2011-11-10 2013-12-27 Inst Biophytis Sas Phytoecdysones pour leur utilisation dans la stabilisation du poids apres un regime amaigrissant
CN102766186B (zh) * 2012-08-03 2015-07-15 玉溪市维和生物技术有限责任公司 富含蜕皮激素的植物标准提取物的制备方法及应用
FR3035589B1 (fr) * 2015-04-30 2019-12-13 Biophytis Composition pour la protection des cellules de l'epithelium pigmentaire retinien
CN105343466B (zh) * 2015-11-16 2019-01-18 南阳理工学院 一种治疗冠心病的中药组合物
FR3093640B1 (fr) * 2019-03-15 2021-10-01 Biophytis Phytoecdysones et leurs dérivés pour leur utilisation dans le traitement de maladies neuromusculaires

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150099022A1 (en) 2011-12-13 2015-04-09 Institut Biophytis Sas Phytoecdysones for use in improving the muscle quality of obese and/or sarcopenic mammals
US20170136041A1 (en) 2011-12-13 2017-05-18 Biophytis Sa Method of improving the muscle quality of obese and/or sarcopenic mammals using phytoecdysones
WO2015151066A1 (en) 2014-04-04 2015-10-08 Polifenoles Naturales, S.L. Treatment of sarcopenia with ecdysteroids
JP2017516851A (ja) 2014-05-20 2017-06-22 ビオフィティス 化合物及び筋肉の質を改善するためのその使用
US20160220624A1 (en) 2015-02-03 2016-08-04 Naturex Sa Compositions and Methods for Improved Muscle Metabolism
WO2016166480A1 (fr) 2015-04-16 2016-10-20 Metabrain Research Dérives utiles dans le traitement de l'atrophie musculaire
JP2020517697A (ja) 2017-04-28 2020-06-18 ビオフィティス 医薬品グレードの２０−ヒドロキシエクジソン抽出物、その使用、およびその調製
JP2020517712A (ja) 2017-04-28 2020-06-18 ビオフィティス ミオパチーの治療における２０−ヒドロキシエクジソンおよびその誘導体の使用

Also Published As

Publication number Publication date
US20210369735A1 (en) 2021-12-02
US20230158046A1 (en) 2023-05-25
WO2019166717A1 (fr) 2019-09-06
FR3078252B1 (fr) 2020-08-14
CN111954534A (zh) 2020-11-17
EP3758709A1 (fr) 2021-01-06
FR3078252A1 (fr) 2019-08-30
JP2021516228A (ja) 2021-07-01
KR20200128058A (ko) 2020-11-11
ES3039265T3 (en) 2025-10-20
EP3758709B1 (fr) 2025-07-09
BR112020017492A2 (pt) 2020-12-22
EP3758709C0 (fr) 2025-07-09

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