FR3078252B1 - Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation - Google Patents

Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation Download PDF

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Publication number
FR3078252B1
FR3078252B1 FR1851778A FR1851778A FR3078252B1 FR 3078252 B1 FR3078252 B1 FR 3078252B1 FR 1851778 A FR1851778 A FR 1851778A FR 1851778 A FR1851778 A FR 1851778A FR 3078252 B1 FR3078252 B1 FR 3078252B1
Authority
FR
France
Prior art keywords
prevention
loss
muscle strength
phytoecdysones
strength during
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1851778A
Other languages
English (en)
French (fr)
Other versions
FR3078252A1 (fr
Inventor
Pierre Dilda
Mathilde Latil
Rene Lafont
Stanislas Veillet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sorbonne Universite
Biophytis SA
Original Assignee
Sorbonne Universite
Biophytis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1851778A priority Critical patent/FR3078252B1/fr
Application filed by Sorbonne Universite, Biophytis SA filed Critical Sorbonne Universite
Priority to CN201980025318.6A priority patent/CN111954534A/zh
Priority to BR112020017492-0A priority patent/BR112020017492A2/pt
Priority to JP2020545181A priority patent/JP7386798B2/ja
Priority to US16/976,189 priority patent/US20210369735A1/en
Priority to PCT/FR2019/050392 priority patent/WO2019166717A1/fr
Priority to KR1020207027259A priority patent/KR20200128058A/ko
Priority to ES19711977T priority patent/ES3039265T3/es
Priority to EP19711977.9A priority patent/EP3758709B1/fr
Publication of FR3078252A1 publication Critical patent/FR3078252A1/fr
Application granted granted Critical
Publication of FR3078252B1 publication Critical patent/FR3078252B1/fr
Priority to US18/158,859 priority patent/US20230158046A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR1851778A 2018-02-28 2018-02-28 Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation Active FR3078252B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR1851778A FR3078252B1 (fr) 2018-02-28 2018-02-28 Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
EP19711977.9A EP3758709B1 (fr) 2018-02-28 2019-02-20 Phytoecdysones pour leur utilisation dans la prévention de la perte de force musculaire lors d'une immobilisation
JP2020545181A JP7386798B2 (ja) 2018-02-28 2019-02-20 固定中の筋力低下の防止に使用する植物エクジソン
US16/976,189 US20210369735A1 (en) 2018-02-28 2019-02-20 Phytoecdysones for use in the prevention of muscle strength loss during immobilisation
PCT/FR2019/050392 WO2019166717A1 (fr) 2018-02-28 2019-02-20 Phytoecdysones pour leur utilisation dans la prévention de la perte de force musculaire lors d'une immobilisation
KR1020207027259A KR20200128058A (ko) 2018-02-28 2019-02-20 고정 동안 근육 강도 손실 예방에 사용하기 위한 피토엑디손
CN201980025318.6A CN111954534A (zh) 2018-02-28 2019-02-20 用于预防固定期间肌力丧失的植物性蜕皮素
BR112020017492-0A BR112020017492A2 (pt) 2018-02-28 2019-02-20 Composição
ES19711977T ES3039265T3 (en) 2018-02-28 2019-02-20 Phytoecdysones for use in the prevention of muscle strength loss during immobilisation
US18/158,859 US20230158046A1 (en) 2018-02-28 2023-01-24 Phytoecdysones for use in the prevention of muscle strength loss during immobilisation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1851778 2018-02-28
FR1851778A FR3078252B1 (fr) 2018-02-28 2018-02-28 Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation

Publications (2)

Publication Number Publication Date
FR3078252A1 FR3078252A1 (fr) 2019-08-30
FR3078252B1 true FR3078252B1 (fr) 2020-08-14

Family

ID=62528604

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1851778A Active FR3078252B1 (fr) 2018-02-28 2018-02-28 Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation

Country Status (9)

Country Link
US (2) US20210369735A1 (https=)
EP (1) EP3758709B1 (https=)
JP (1) JP7386798B2 (https=)
KR (1) KR20200128058A (https=)
CN (1) CN111954534A (https=)
BR (1) BR112020017492A2 (https=)
ES (1) ES3039265T3 (https=)
FR (1) FR3078252B1 (https=)
WO (1) WO2019166717A1 (https=)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH684572A5 (fr) * 1992-04-16 1994-10-31 Jean Louis Connat Nourriture à base d'ecdystéroîdes abaissant la fertilité des parasites hématophages.
AU2003902621A0 (en) * 2003-05-27 2003-06-12 Commonwealth Scientific And Industrial Research Organisation Ecdysone receiptor ligand-binding domain structure
FR2924346B1 (fr) * 2007-11-30 2010-02-19 Inst Biophytis Sas Utilisation de phytoecdysones dans la preparation d'une composition pour agir sur le syndrome metabolique.
EP2265116A4 (en) * 2008-03-14 2013-02-06 Intrexon Corp STEROID LIGANDS AND THEIR USE IN GENE SWITCH MODULATION
RU2390270C1 (ru) * 2009-03-13 2010-05-27 Общество С Ограниченной Ответственностью "Парафарм" Биологически активная добавка к пище
WO2010132982A1 (en) * 2009-05-18 2010-11-25 Ottawa Hospital Research Institute Treatment of muscle disease characterized by insulin resistance
AU2011343970A1 (en) * 2010-12-13 2013-07-04 Rutgers University Methods of producing and using brassinosteroids to promote growth, repair and maintenance of skeletal muscle and skin
FR2982489B1 (fr) * 2011-11-10 2013-12-27 Inst Biophytis Sas Phytoecdysones pour leur utilisation dans la stabilisation du poids apres un regime amaigrissant
FR2983733B1 (fr) * 2011-12-13 2017-12-22 Inst Biophytis Sas Phytoecdysones pour leur utilisation dans l'amelioration de la qualite musculaire de mammiferes obeses et/ou sarcopeniques
CN102766186B (zh) * 2012-08-03 2015-07-15 玉溪市维和生物技术有限责任公司 富含蜕皮激素的植物标准提取物的制备方法及应用
US20190054093A1 (en) * 2014-04-04 2019-02-21 Nektium Pharma Sl Treatment of sarcopenia with ecdysteroids
FR3021318B1 (fr) * 2014-05-20 2017-04-28 Inst Biophytis Produits derives de la 20-hydroxyecdysone et leur utilisation dans la preparation de medicaments
US9700589B2 (en) * 2015-02-03 2017-07-11 Naturex Sa Compositions and methods for improved muscle metabolism
FR3035105A1 (fr) * 2015-04-16 2016-10-21 Metabrain Res Derives utiles dans le traitement de l'atrophie musculaire
FR3035589B1 (fr) * 2015-04-30 2019-12-13 Biophytis Composition pour la protection des cellules de l'epithelium pigmentaire retinien
CN105343466B (zh) * 2015-11-16 2019-01-18 南阳理工学院 一种治疗冠心病的中药组合物
FR3065644B1 (fr) * 2017-04-28 2020-02-21 Biophytis Extrait de 20-hydroxyecdysone de qualite pharmaceutique, son utilisation et sa preparation
FR3093640B1 (fr) * 2019-03-15 2021-10-01 Biophytis Phytoecdysones et leurs dérivés pour leur utilisation dans le traitement de maladies neuromusculaires

Also Published As

Publication number Publication date
US20210369735A1 (en) 2021-12-02
US20230158046A1 (en) 2023-05-25
WO2019166717A1 (fr) 2019-09-06
CN111954534A (zh) 2020-11-17
EP3758709A1 (fr) 2021-01-06
FR3078252A1 (fr) 2019-08-30
JP2021516228A (ja) 2021-07-01
KR20200128058A (ko) 2020-11-11
JP7386798B2 (ja) 2023-11-27
ES3039265T3 (en) 2025-10-20
EP3758709B1 (fr) 2025-07-09
BR112020017492A2 (pt) 2020-12-22
EP3758709C0 (fr) 2025-07-09

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