JP7298966B2 - 医療用アダプタ及び圧力調節バイアルアダプタ - Google Patents
医療用アダプタ及び圧力調節バイアルアダプタ Download PDFInfo
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
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- A61J1/14—Details; Accessories therefor
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- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/202—Separating means
- A61J1/2037—Separating means having valve means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2055—Connecting means having gripping means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2072—Venting means for internal venting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/9029—With coupling
- Y10T137/9138—Flexible
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Description
本出願は、2013年1月23日に出願した米国特許仮出願第61/755,800号、名称「PRESSURE-REGULATING VIAL ADAPTORS」、2013年3月14日に出願した米国特許仮出願第61/785,874号、名称「PRESSURE-REGULATING VIAL ADAPTORS」、および2013年11月27日に出願した米国特許仮出願第 61/909,940号、名称「PRESSURE-REGULATING VIAL ADAPTORS」の利益を主張するものである。上記の特許出願それぞれの内容全体が、参照により本明細書に組み込まれ、本明細書の一部をなすものとする。
[0013]いくつかの実施形態において、調節器アセンブリは、吸込み弁が開放配置にあるときに調節器アセンブリの内部に流体連通するフィルタ室を含むことができる。フィルタ室は内断面を有する内壁と外断面を有する外壁とを持つことができる。いくつかの実施形態において、フィルタ室は調節器アセンブリ流路の少なくとも一部を取り囲むことができる。いくつかの場合には、調節器アセンブリは、フィルタ室内にあって、フィルタ室の内断面とフィルタ室の外断面との間に画定される空間を充填する、フィルタを含んでいる。いくつかの例では、フィルタ室の内断面は弁座の外幅によって少なくとも部分的に画定される。いくつかの場合において、弁座の内幅は調節器アセンブリ流路の少なくとも一部を画定する。
る。
弁2070を通って流れることを阻止することができる。
Claims (20)
- バイアルから医療用物質を引き出すことのできる医療用アダプタであって、
前記医療用アダプタは、
医療用コネクタインタフェースと、
前記医療用コネクタインタフェースと遠位アクセスポートとの間に延び、封止された容器から薬剤流体を取り出すことが可能なアクセス流路と、
遠位部及び近位部を含む調節器流路と、
前記調節器流路の前記近位部と流体連通する調節器アセンブリであって、
貯蔵幅及び内部貯蔵体積を有する貯蔵領域と、
前記調節器流路の前記近位部と流体連通する可撓性エンクロージャであって、前記可撓性エンクロージャは、前記可撓性エンクロージャが前記貯蔵領域内にある貯蔵配置と、展開配置との間を転移可能であり、前記可撓性エンクロージャは前記展開配置にあるときは展開体積及び展開幅を有する、前記可撓性エンクロージャと、
バイアル内の圧力を調整するために外気と調節器流路との間の流体連通を促進するように構成された吸込みポートと、
前記貯蔵領域に嵌め込まれており、前記可撓性エンクロージャが貯蔵配置と展開配置との間を転移する際に摩擦抵抗を前記可撓性エンクロージャの少なくとも一部に提供して、前記可撓性エンクロージャが前記展開配置に迅速に転移することを抑制又は防止するように構成されたエンクロージャカバーと、
を有する調節器アセンブリと、
を備え、
前記医療用アダプタは、前記バイアルから第1の体積の薬物流体を引き出すことができるように構成されており、前記展開体積が前記薬物流体の前記第1の体積よりも小さい場合に前記吸込みポートから前記バイアル内へ流体を流すことを許容することにより前記バイアル内の圧力を調節するように構成されている、医療用アダプタ。 - 前記エンクロージャカバーは、弾性材料、可撓性材料、及び伸縮性材料のうちの少なくとも1つで作製されている、請求項1に記載の医療用アダプタ。
- 前記エンクロージャカバーは、前記貯蔵領域の前記医療用コネクタインタフェースとは反対の側に開口を含む、請求項1に記載の医療用アダプタ。
- 前記エンクロージャカバーは、前記可撓性エンクロージャが前記展開配置に転移するときに前記開口の付近で折れ曲がるように構成されている、請求項3に記載の医療用アダプタ。
- 前記吸込みポートは前記調節器流路の前記遠位部と流体連通する一方向弁をさらに含み、前記一方向弁は開放配置と閉鎖配置との間を転移可能であり、前記一方向弁は、前記一方向弁が開放配置にあるときに周囲環境から前記調節器アセンブリの内部への流体連通を促進する、請求項1に記載の医療用アダプタ。
- 濾過された空気を、前記可撓性エンクロージャを迂回する吸込み流体経路に沿って前記一方向弁を通過して選択的に引き込むように構成されている、請求項5に記載の医療用アダプタ。
- 前記一方向弁と前記周囲環境との間の流体流路内に位置し、汚染物が前記バイアル中へ導入されることを抑制又は防止するように構成されたフィルタをさらに含む、請求項6に記載の医療用アダプタ。
- 前記可撓性エンクロージャは、金属成分を有する材料を含む、請求項1に記載の医療用アダプタ。
- 前記展開体積は、前記内部貯蔵体積の3,000%以上である、請求項1に記載の医療用アダプタ。
- 前記展開幅は、前記貯蔵幅の110%よりも大きい、請求項1に記載の医療用アダプタ。
- バイアルから医療用物質を引き出すことのできる医療用アダプタであって、
前記医療用アダプタは、
医療用コネクタインタフェースと、
前記医療用コネクタインタフェースの遠位側に位置し、前記バイアル内に少なくとも部分的に延びるように構成された穿刺部材と、
前記医療用コネクタインタフェースと前記穿刺部材の遠位アクセスポートとの間に延びるアクセス流路と、
遠位部及び近位部を含む調節器流路と、
バイアル内の圧力を調整するために外気と調節器流路との間の流体連通を促進するように構成された吸込みポートと、
前記調節器流路の前記近位部と流体連通する可撓性エンクロージャであって、前記可撓性エンクロージャは、前記可撓性エンクロージャが拡張していない体積を有する非拡張配置と、前記可撓性エンクロージャが拡張した体積を有する拡張配置との間を転移可能である、前記可撓性エンクロージャと、
前記可撓性エンクロージャが前記非拡張配置にあるときに前記可撓性エンクロージャを少なくとも部分的に取り囲むエンクロージャカバーであって、前記エンクロージャカバーは、前記可撓性エンクロージャの前記医療用コネクタインタフェースとは反対の側に開口を有し、前記開口は、前記穿刺部材の長軸に平行に測った前記可撓性エンクロージャの幅よりも小さい幅を有する、前記エンクロージャカバーと、
を備え、
前記医療用アダプタは、前記バイアルから前記可撓性エンクロージャの拡張体積よりも大きい第1の体積の薬物流体を引き出すことを許容するように構成されている、医療用アダプタ。 - 前記医療用コネクタインタフェースは、シリンジとの針を用いない接続を促進するように構成されている、請求項11に記載の医療用アダプタ。
- 濾過ポートをさらに含み、周辺の空気は前記濾過ポートを通過して前記調節器流路に入ることができる、請求項11に記載の医療用アダプタ。
- 濾過ポートは前記可撓性エンクロージャの遠位側に位置する、請求項13に記載の医療用アダプタ。
- 前記可撓性エンクロージャと前記穿刺部材との間の前記調節器流路に位置する調節器弁を含む、請求項11に記載の医療用アダプタ。
- 前記調節器弁は、前記バイアルから前記可撓性エンクロージャへの液体の通過を抑制するように構成されている、請求項15に記載の医療用アダプタ。
- 前記調節器弁は、流体が前記調節器流路の前記遠位部に向かって前記調節器弁を第1のクラッキング圧力で通過できるように構成され、また、流体が前記可撓性エンクロージャに向かって第2のクラッキング圧力で通過できるように構成されており、前記第1のクラッキング圧力は前記第2のクラッキング圧力よりも小さい、請求項15に記載の医療用アダプタ。
- 前記調節器弁は、少なくとも1つのスリットが入ったドーム形弁である、請求項15に記載の医療用アダプタ。
- 前記可撓性エンクロージャは、非拡張配置にあるときに少なくとも2つの非平行線に沿って折り畳まれる、請求項11に記載の医療用アダプタ。
- 前記可撓性エンクロージャが前記非拡張配置にあるとき、前記エンクロージャカバーは、前記可撓性エンクロージャと前記医療用コネクタインタフェースとの間に位置する内側リップと、前記医療用コネクタインタフェースとは反対の側に位置する外側リップとを含む、請求項11に記載の医療用アダプタ。
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Application Number | Priority Date | Filing Date | Title |
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US201361755800P | 2013-01-23 | 2013-01-23 | |
US61/755,800 | 2013-01-23 | ||
US201361785874P | 2013-03-14 | 2013-03-14 | |
US61/785,874 | 2013-03-14 | ||
US201361909940P | 2013-11-27 | 2013-11-27 | |
US61/909,940 | 2013-11-27 | ||
JP2017194824A JP6437612B2 (ja) | 2013-01-23 | 2017-10-05 | 医療用アダプタ及び圧力調節バイアルアダプタ |
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JP2017194824A Active JP6437612B2 (ja) | 2013-01-23 | 2017-10-05 | 医療用アダプタ及び圧力調節バイアルアダプタ |
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JP (3) | JP6224733B2 (ja) |
AU (2) | AU2014209594B2 (ja) |
CA (1) | CA2899000C (ja) |
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