US3542240A - Partially assembled bulk parenteral solution container and adminstration set - Google Patents

Partially assembled bulk parenteral solution container and adminstration set Download PDF

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Publication number
US3542240A
US3542240A US3542240DA US3542240A US 3542240 A US3542240 A US 3542240A US 3542240D A US3542240D A US 3542240DA US 3542240 A US3542240 A US 3542240A
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United States
Prior art keywords
cap
bottle
partially assembled
solution container
parenteral solution
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Expired - Lifetime
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Ida Solowey
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Ida Solowey
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A61M2005/1623Details of air intake

Description

United States Patent 72] Inventor Id Solowgy [50] Field of Search 222/83, P.0. Box 34, Fresh Meadows Station, 2 Flushing, New York 11365 525; 215/75, 40, 73.79, 56; l28/lnq [211 App]. No. 767,315 [22] Filed O t. 14, 1963 References Cited [45] Patented Nov. 24,1970 UNITED STATES PATENTS 2,849,156 8/1958 Mansted 222/83 3,091,374 5/1963 Schwartzman 222/520X Primary Examiner-Robert B. Reeves I Assistant Examiner-11. S. Lane [54] PARTIALLY ASSEMBLED BULK PARENTERAL ggiJ CONTAINER AND ADMINISTRATION ABSTRACT: A mechanism for extracting medication from a 4 Claim 3 D in F bottle in a contamination free manner, the mechanism includg ing a movable cap on the neck of a bottle, the cap carrying a [52] US. Cl. 222/83, needle for puncturing a diaphragm closing the mouth of the 222/479; 220/38, 220/41 bottle, and a flexible sleeve antiseptically sealing the cap to [51] Int. Cl. B67b 7/2'4 the bottle.

Z 2 Z5 3 Z5 4 f p I Z0{ Z? Z! l 1 37 r I? 39 as 36 3 2k, JI \r M- Patented Nov. 24, 1970 3,542,240

ready enjoined so to prevent contamination, and wherein external manipulation thereof places them into operative condi tion. l

. Other objects are to provide a partially assembled bulk parenteral solution container and administration set which is simple in design, inexpensive to manufacture, rugged inconstruction, easy to use and efficient in operation.

These and other objects will be readily evident upon a study of the following specification and the accompanying drawing wherein:

FIG. 1 is a side cross-sectional view of the invention.

FIG. 2 is an exploded perspective view of the invention.

FIG. 3 is a side cross-sectional view of a modified form of the invention.

Referring now tothe drawing in detail, the reference numeral represents a partially assembled bulk parenteral solution container and administration set according to the present invention, wherein there is an administrative cap 11 over the mouth 12 of a bottle 13.

The cap 11 includes plastic body 14 having internal thread 15 engaged on external thread 16 of the bottle. A rubber plug 17 having a thin central diaphragm 18 is fitted into the bottle mouth sealing the bottle interior 19. A central needle 20 integrally formed with the body 14 carries a passage 21 therethrough which communicates with a drip chamber 22 made of transparent plastic and fitted over a nipple 23 formed on the body. Another passage 24 extends through the needle 20 and is parallel topassage 21; the passage 24 communicating with an air filter unit 25 formed on the body. The unit 25 includes a check valve 26 comprised of steel ball 27 normally urged by a compression coil spring 28 against a valve seat 29 so to normally close the passage 24. A filter screen 30 is fitted over the end of the passage 24 and secured in position by a removable bezel 31. Q

The drip chamber 22 is connected to one end of a hose 32 having a manually closable clamp 33 along the length thereof for purpose of squeezing the hose so to seal the hose passage fully or in part for controlling flow volume therethrough.

The bottle 13 includes a circular flange 34 integrally formed around the neck 35 thereof. A flexible sleeve 36 has a central opening at one end fitted around the cap 11; the cap having a bead 37 which fits into a groove 38 of the sleeve. The opposite end of the sleeve has'an upward turned edge 39, which is forced down to snap around the flange 34, so that the sleeve can not be accidentally removed during operational use, thereby sealing the contents from contamination. The sleeve 36 can be made integral with the body 14.

In preoperative use, the device is initially in the position shown in FIG. 1, with edge 39 in the sealed solid linepositio'n. Upon rotation of the body relative to the bottle the threads 15 and 16 cause the body to descend, causing the needle to punc-' ture the diaphragm, and allowing the bottle contents to flow out of the passage 21 when the device is inverted. The valve 26 prevents escape of the bottle contents out of the air filter unit 25;

The air filter bezel is removable for adding medication into the cap which will be prevented from flowoutward from the air filter by the checkvalve.

In a modified construction 50 shown in FIG. 3, the cap 51 is vertically, axially slidable on the bottle instead of being rotatable as above described. In this form of the invention, the cap includes a relativel thin integral formed sleeve 52. The cap 51 and the sleeve 2 are both made of resilient material and are integrally formed together. The interior side wall of the cap includes an upper circular groove 57a and a lower circular groove 57b. The bottle includes on the outer side of the bottle neck an upper bead 55 and a lower head 56. Prior to operative use, an upturned resilient lower edge 62 of the sleeve 52 is snapped around a flange 53 integrally formed on the bottle (see dotted lines). In operative use, the cap is simply pushed axially causing the cap groove to disengage bead 55 from the groove 57b. As the cap descends, the groove 57b snaps over bead 56, while at the same-instant, the needles 60 and 61 pierce the diaphragm. The cap carries drip chamber 58 and air filter 59, each with its own needle 60 and 61 respectively. The needles pierce the plug diaphragm upon downward travel, thus allowing outward flow of the formerly sealed bottle content. The air filter 59 is provided with a valve similar to the ball valve 27 of FIG. 1 to prevent flow outward through the filter.

While various changes may be made in the detail construction, it is understood that such changes will be within the spirit and scope of the present invention.

lclaim:

1. In a partially assembled bulk parenteral solution container and administration set, the combination of a bottle hav ing a neck surrounding an open mouth, a movable cap mounted on the neck adjacent the mouth, a frangible plug sealingly fixed within said mouth, and a flexible sleeve secured at right angles to the cap and having a longitudinal portion extending towards the bottle beyond the mouth, said portion being securable to the bottle radially spaced from the neck, said cap having a passage extending from the mouth through the cap.

2. The combination as set forth in claim 1 wherein said cap comprises a body having an internal thread engaging an external thread on said bottle neck, a central needle integrally formed on said body a passage through said needle communicating with a drip chamber secured on a nipple formed on said body, a second passage through said needle communicating with an air filter on said body, said air filter comprising a check valve having a steel ball normally urged against a valve seat by a spring to close said second passage, said filter having a filter screen across the end of said second passage secured by a bezel, and said plug including a central thin diaphragm rupturable by said needle.

3. The combination as set forth in claim 2 wherein said bottle includes a flange around said neck, one end of said sleeve rigidly secured to said flange, the opposite end of said sleeve having a groove receiving rotationally free a bead formed around said cap body.

4. The combination as set forth in claim 1 wherein said bottle neck includes a pair of axially spaced apart beads selectively engaging a groove on said cap, said sleeve being integral at one end with said cap, the opposite end of said sleeve fixedly engaging a flange around said bottle neck a drip chamber and an air filter on said cap, said drip chamber and air filter each having a hollow needle in alinement to pierce a thin diaphragm centrally formed on said plug when said cap is axially pushed.

US3542240D 1968-10-14 1968-10-14 Partially assembled bulk parenteral solution container and adminstration set Expired - Lifetime US3542240A (en)

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Cited By (75)

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US3783895A (en) * 1971-05-04 1974-01-08 Sherwood Medical Ind Inc Universal parenteral fluid administration connector
US3807467A (en) * 1970-04-08 1974-04-30 Sherwood Medical Ind Inc Medicament filling unit
US3827601A (en) * 1973-03-23 1974-08-06 J Magrath Hand powered liquid dispenser of the metering type
US3856185A (en) * 1973-12-26 1974-12-24 Ciba Geigy Corp Single dose, replaceable supply air pressure operated dispenser
US3892235A (en) * 1971-07-27 1975-07-01 Respiratory Care Multi-use inhalation therapy apparatus
US4076027A (en) * 1976-05-07 1978-02-28 Sherwood Medical Industries Inc. Fluid transfer device
US4128098A (en) * 1976-12-06 1978-12-05 American Hospital Supply Corporation Valved spike transfer device
US4558823A (en) * 1984-03-02 1985-12-17 Regina Corporation Spotting control and trigger assembly
EP0169722A2 (en) * 1984-07-26 1986-01-29 Henley Investments, Inc. Drip feed device
US4568336A (en) * 1984-04-26 1986-02-04 Microbiological Applications, Inc. Pre-filled hypodermic syringes
US4570856A (en) * 1984-03-02 1986-02-18 Regina Corporation Liquid and detergent mixing chamber and valves
US4575007A (en) * 1984-03-02 1986-03-11 Regina Corporation Mixing control for water and cleaning fluid
US4610374A (en) * 1984-10-29 1986-09-09 Dougherty Brothers Company Apparatus for mixing flowable materials in sealed containers
US4648873A (en) * 1985-05-06 1987-03-10 Quest Medical, Inc. Adapter for intravenous delivery set
US4676287A (en) * 1984-03-02 1987-06-30 The Regina Company Inc. Cartridge and docking port for a cleaning device
US4708260A (en) * 1984-10-26 1987-11-24 Kiwi Coders Corporation Hydraulic coupling comprising a sealed closure and connection fitting for a flexible container
US4712740A (en) * 1984-03-02 1987-12-15 The Regina Co., Inc. Venturi spray nozzle for a cleaning device
US4770323A (en) * 1986-01-17 1988-09-13 Aerosol Inventions And Development S.A. A.I.D. S.A. Sterile packaging of liquid and semi-liquid fluids
US4787429A (en) * 1986-07-25 1988-11-29 Farmitalia Carlo Erba S.P.A. Device for coupling a small tube to an apparatus adapted for fitting a syringe to a drug holding bottle
US4857068A (en) * 1986-12-22 1989-08-15 Miles Laboratories, Inc. Universal spike for use with rigid and collapsible parenteral fluid dispensing container
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US4888008A (en) * 1987-03-03 1989-12-19 Sherwood Medical Company Vented spike connection component
US4919658A (en) * 1987-06-05 1990-04-24 Institute Municipal D'assistencia Sanitaria Connection for catheters, perfusion units and flasks of liquid to be perfused
US4997429A (en) * 1988-12-28 1991-03-05 Sherwood Medical Company Enteral bottle cap with vent valve
US5041105A (en) * 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US5086950A (en) * 1988-11-14 1992-02-11 Diversey Corporation Liquid dispensing apparatus
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
US6142750A (en) * 1998-11-30 2000-11-07 The Procter & Gamble Company Gear pump and replaceable reservoir for a fluid sprayer
US6321941B1 (en) 2000-04-20 2001-11-27 The Procter & Gamble Company Consumer safe fitment for connecting a reservoir to a dispensing appliance
US6386392B1 (en) 1999-11-02 2002-05-14 The Procter & Gamble Company Reservoirs for use with cleaning devices
US20020179635A1 (en) * 1999-12-01 2002-12-05 Incardona Silvia Deborah Reclosable fitment for connecting a reservoir to a dispensing appliance
US6685056B1 (en) 1999-08-05 2004-02-03 The Procter & Gamble Company Dispensing device comprising a reservoir and attachment means provided with protected piercing means
US20040050959A1 (en) * 2002-05-28 2004-03-18 Mazooji Amber N. Automated cleansing sprayer
US20040153047A1 (en) * 2002-11-18 2004-08-05 Ricardo Blank Connector device
US20050223823A1 (en) * 2004-04-13 2005-10-13 Sigma-Aldrich Co. Container with a frangible seal
US20070093775A1 (en) * 2005-10-20 2007-04-26 Sherwood Services Ag Connector for enteral fluid delivery set
US20070267425A1 (en) * 2006-01-27 2007-11-22 Yoram Gill Dispenser device
ITMO20080295A1 (en) * 2008-11-18 2010-05-19 Lucomed Spa A connecting device to pierceable barrier
US20100204670A1 (en) * 2009-02-10 2010-08-12 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US20100204671A1 (en) * 2009-02-10 2010-08-12 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US20100308056A1 (en) * 2007-05-24 2010-12-09 Torsten Brandenburger Closure cap for a container for receiving liquids and in particular an enteral nutrient solution, and container having such a closure cap
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US7896859B2 (en) 2005-10-20 2011-03-01 Tyco Healthcare Group Lp Enteral feeding set
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US7942860B2 (en) 2007-03-16 2011-05-17 Carmel Pharma Ab Piercing member protection device
US7975733B2 (en) 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
US8328772B2 (en) 2003-01-21 2012-12-11 Carmel Pharma Ab Needle for penetrating a membrane
CN102872500A (en) * 2012-10-24 2013-01-16 刘玮 Two-channel transfusion head of automatically controlling liquid and gas to be transfused by time phases
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
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US8545475B2 (en) * 2002-07-09 2013-10-01 Carmel Pharma Ab Coupling component for transmitting medical substances
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US8622985B2 (en) 2007-06-13 2014-01-07 Carmel Pharma Ab Arrangement for use with a medical device
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US20140097184A1 (en) * 2012-10-09 2014-04-10 Coravin, Llc Method and apparatus for gas cylinder sealing
US8790330B2 (en) 2008-12-15 2014-07-29 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US8827978B2 (en) 2007-09-17 2014-09-09 Carmel Pharma Ab Bag connector
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US8882738B2 (en) 2006-04-12 2014-11-11 Icu Medical, Inc. Locking vial adaptors and methods
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
US9107808B2 (en) 2007-03-09 2015-08-18 Icu Medical, Inc. Adaptors for removing medicinal fluids from a container
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US9610217B2 (en) 2012-03-22 2017-04-04 Icu Medical, Inc. Pressure-regulating vial adaptors
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US9810375B2 (en) 2015-06-30 2017-11-07 Coravin, Inc. Engagement of gas cylinder with gas dispenser
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Cited By (121)

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Publication number Priority date Publication date Assignee Title
US3807467A (en) * 1970-04-08 1974-04-30 Sherwood Medical Ind Inc Medicament filling unit
US3783895A (en) * 1971-05-04 1974-01-08 Sherwood Medical Ind Inc Universal parenteral fluid administration connector
US3892235A (en) * 1971-07-27 1975-07-01 Respiratory Care Multi-use inhalation therapy apparatus
US3827601A (en) * 1973-03-23 1974-08-06 J Magrath Hand powered liquid dispenser of the metering type
US3856185A (en) * 1973-12-26 1974-12-24 Ciba Geigy Corp Single dose, replaceable supply air pressure operated dispenser
US4076027A (en) * 1976-05-07 1978-02-28 Sherwood Medical Industries Inc. Fluid transfer device
US4128098A (en) * 1976-12-06 1978-12-05 American Hospital Supply Corporation Valved spike transfer device
US4558823A (en) * 1984-03-02 1985-12-17 Regina Corporation Spotting control and trigger assembly
US4676287A (en) * 1984-03-02 1987-06-30 The Regina Company Inc. Cartridge and docking port for a cleaning device
US4712740A (en) * 1984-03-02 1987-12-15 The Regina Co., Inc. Venturi spray nozzle for a cleaning device
US4570856A (en) * 1984-03-02 1986-02-18 Regina Corporation Liquid and detergent mixing chamber and valves
US4575007A (en) * 1984-03-02 1986-03-11 Regina Corporation Mixing control for water and cleaning fluid
US4568336A (en) * 1984-04-26 1986-02-04 Microbiological Applications, Inc. Pre-filled hypodermic syringes
EP0169722A2 (en) * 1984-07-26 1986-01-29 Henley Investments, Inc. Drip feed device
EP0169722A3 (en) * 1984-07-26 1986-12-03 Henley Investments, Inc. Drip feed device
US4576594A (en) * 1984-07-26 1986-03-18 Warner-Lambert Company Vented drip chamber for use with a syringe
US4708260A (en) * 1984-10-26 1987-11-24 Kiwi Coders Corporation Hydraulic coupling comprising a sealed closure and connection fitting for a flexible container
US4610374A (en) * 1984-10-29 1986-09-09 Dougherty Brothers Company Apparatus for mixing flowable materials in sealed containers
US4648873A (en) * 1985-05-06 1987-03-10 Quest Medical, Inc. Adapter for intravenous delivery set
US4770323A (en) * 1986-01-17 1988-09-13 Aerosol Inventions And Development S.A. A.I.D. S.A. Sterile packaging of liquid and semi-liquid fluids
US4787429A (en) * 1986-07-25 1988-11-29 Farmitalia Carlo Erba S.P.A. Device for coupling a small tube to an apparatus adapted for fitting a syringe to a drug holding bottle
US4857068A (en) * 1986-12-22 1989-08-15 Miles Laboratories, Inc. Universal spike for use with rigid and collapsible parenteral fluid dispensing container
US4888008A (en) * 1987-03-03 1989-12-19 Sherwood Medical Company Vented spike connection component
US5041105A (en) * 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4919658A (en) * 1987-06-05 1990-04-24 Institute Municipal D'assistencia Sanitaria Connection for catheters, perfusion units and flasks of liquid to be perfused
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
US5137511A (en) * 1987-07-08 1992-08-11 Duoject Medical Systems Inc. Syringe
US5086950A (en) * 1988-11-14 1992-02-11 Diversey Corporation Liquid dispensing apparatus
US4997429A (en) * 1988-12-28 1991-03-05 Sherwood Medical Company Enteral bottle cap with vent valve
US6142750A (en) * 1998-11-30 2000-11-07 The Procter & Gamble Company Gear pump and replaceable reservoir for a fluid sprayer
US6328543B1 (en) 1998-11-30 2001-12-11 The Procter & Gamble Company Gear pump and replaceable reservoir for a fluid sprayer
US6685056B1 (en) 1999-08-05 2004-02-03 The Procter & Gamble Company Dispensing device comprising a reservoir and attachment means provided with protected piercing means
US6386392B1 (en) 1999-11-02 2002-05-14 The Procter & Gamble Company Reservoirs for use with cleaning devices
US20020179635A1 (en) * 1999-12-01 2002-12-05 Incardona Silvia Deborah Reclosable fitment for connecting a reservoir to a dispensing appliance
US6971589B2 (en) * 1999-12-01 2005-12-06 The Procter & Gamble Company Reclosable fitment for connecting a reservoir to a dispensing appliance
US6321941B1 (en) 2000-04-20 2001-11-27 The Procter & Gamble Company Consumer safe fitment for connecting a reservoir to a dispensing appliance
US10123938B2 (en) 2002-03-26 2018-11-13 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US20040050959A1 (en) * 2002-05-28 2004-03-18 Mazooji Amber N. Automated cleansing sprayer
US7837132B2 (en) * 2002-05-28 2010-11-23 S.C. Johnson & Son, Inc. Automated cleansing sprayer
US8550378B2 (en) 2002-05-28 2013-10-08 S.C. Johnson & Son, Inc. Automated cleansing sprayer
US20110024466A1 (en) * 2002-05-28 2011-02-03 Mazooji Amber N Automated Cleansing Sprayer
US8545475B2 (en) * 2002-07-09 2013-10-01 Carmel Pharma Ab Coupling component for transmitting medical substances
US20040153047A1 (en) * 2002-11-18 2004-08-05 Ricardo Blank Connector device
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
US8328772B2 (en) 2003-01-21 2012-12-11 Carmel Pharma Ab Needle for penetrating a membrane
US7077017B2 (en) * 2004-04-13 2006-07-18 Sigma-Aldrich Co. Container with a frangible seal
WO2005100946A3 (en) * 2004-04-13 2006-06-01 Sigma Aldrich Co Container with a frangible seal
WO2005100946A2 (en) * 2004-04-13 2005-10-27 Sigma-Aldrich Co. Container with a frangible seal
US20050223823A1 (en) * 2004-04-13 2005-10-13 Sigma-Aldrich Co. Container with a frangible seal
US20070093775A1 (en) * 2005-10-20 2007-04-26 Sherwood Services Ag Connector for enteral fluid delivery set
US7896859B2 (en) 2005-10-20 2011-03-01 Tyco Healthcare Group Lp Enteral feeding set
US8357136B2 (en) 2005-10-20 2013-01-22 Covidien Lp Enteral feeding set
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
US20070267425A1 (en) * 2006-01-27 2007-11-22 Yoram Gill Dispenser device
US10327991B2 (en) 2006-04-12 2019-06-25 Icu Medical, Inc. Fluid transfer apparatus with filtered air input
US10327992B2 (en) 2006-04-12 2019-06-25 Icu Medical, Inc. Fluid transfer apparatus with pressure regulation
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US8882738B2 (en) 2006-04-12 2014-11-11 Icu Medical, Inc. Locking vial adaptors and methods
US9005179B2 (en) 2006-04-12 2015-04-14 Icu Medical, Inc. Pressure-regulating apparatus for withdrawing medicinal fluid from a vial
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US9060921B2 (en) 2006-04-12 2015-06-23 Icu Medical, Inc. Air-filtering vial adaptors and methods
US10071020B2 (en) 2006-04-12 2018-09-11 Icu Medical, Inc. Devices for transferring fluid to or from a vial
US10022302B2 (en) 2006-04-12 2018-07-17 Icu Medical, Inc. Devices for transferring medicinal fluids to or from a container
US9662272B2 (en) 2006-04-12 2017-05-30 Icu Medical, Inc. Devices and methods for transferring fluid to or from a vial
US9993390B2 (en) 2006-04-12 2018-06-12 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
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FR2086896A5 (en) 1971-12-31
BE747394A1 (en)

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