US3557778A - Blood specimen collection assembly - Google Patents

Blood specimen collection assembly Download PDF

Info

Publication number
US3557778A
US3557778A US3557778DA US3557778A US 3557778 A US3557778 A US 3557778A US 3557778D A US3557778D A US 3557778DA US 3557778 A US3557778 A US 3557778A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
assembly
fluid
receptacle
chamber
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Elbert L Hughes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ELBERT L HUGHES
Original Assignee
ELBERT L HUGHES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221Valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150259Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150496Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • A61M2039/242Check- or non-return valves designed to open when a predetermined pressure or flow rate has been reached, e.g. check valve actuated by fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • A61M2039/2473Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • A61M2039/2473Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
    • A61M2039/248Ball-valve

Abstract

A blood specimen collection assembly having a fluid inlet and a fluid outlet with valve means disposed within the assembly for movement to and from an open and closed position whereby to prevent the backflow of testing fluid from a specimen receptacle, which is coupled with the assembly, into the patient''s bloodstream during use of the assembly. The specimen receptacle is in the form of an evacuated container and is coupled with the collection assembly when the same is in use, the receptacle being in communication with the assembly to provide negative pressure through the assembly for opening the valve and withdrawing the specimen, the valve resuming its closed position upon filling of the receptacle.

Description

United States Patent [72] lnventor Elbert L. Hughes Independence, M0. (358 California Ave., Aurora, 111., 60506) {21] Appl. No. 776,347 [22] Filed Nov. 18, 1968 Patented Jan. 26, 1971 [541 BLOOD SPECIMEN COLLECTION ASSEMBLY 1 Claim, 6 Drawing Figs.

1,363,128 12/1920 Kitaoka 128/218 Primary Examiner-Warner H. Camp Att0rney-Schmidt, Johnson, Hovey, Williams & Chase ABSTRACT: A blood specimen collection assembly having a fluid inlet and a fluid outlet with valve means disposed within the assembly for movement to and from an open and closed position whereby to prevent the backflow of testing fluid from a specimen receptacle, which is coupled with the assembly, into the patients bloodstream during use of the assembly. The specimen receptacle is in the form of an evacuated container and is coupled with the collection assembly when the same is in use, the receptacle being in communication with the assembly to provide negative pressure through the assembly for opening the valve and withdrawing the specimen, the valve resuming its closed position upon filling of the receptacle.

BLOOD SPECIMEN COLLECTION ASSEMBLY This invention relates to improvements in devices used for taking blood samples from patients, and more specifically, to a blood collection assembly having check valve means therein to prevent backflow of the blood specimen and testing solution into the bloodstream of the patient.

Although blood specimencollection devices have been used in the past for obtaining a quantity of blood from the patient suitable for subsequent mixing with a test solution, such devices have generally been so constructed that after withdrawing the blood specimen in one container, it was then necessary to transfer the blood into another container carrying the test fluid. This process subjected the blood specimen to possible contamination from various sources and subsequently increased the changes of obtaining invalid results from the test.

In more recent times devices have been developed which combine the specimen container and the test fluid container into one unit such that the blood specimen, upon being withdrawn through a hollow needle inserted in the patients vein, flows directly into the container having the testing solution therein. The test is thus carried out without requiring that the blood be transferred from one container to another. Since the needle remains in the patients arm during mixing of the blood specimen with the test fluid, however, there is a very grave danger that some of the mixture may flow back into the vein before the needle can be removed. Oftentimes the test fluid is of such a nature that only a very small amount need be released into the bloodstream before causing serious damage or even death to the patient being examined.

A primary object of the present invention is to provide a blood specimen collection assembly which includes an evacuated specimen receptacle normally containing an amount of testing fluid therein, which receptacle is adapted to directly receive the blood specimen withdrawn from the patient by the assembly, the assembly additionally including check valve means whereby to prevent baekflow of the blood and fluid mixture from the receptacle into the bloodstream of the patrent.

Another important object of this invention is to provide a blood specimen collection assembly for communication with a specimen receptacle, the assembly having a body provided with a chamber therein, a hollow needle in communication with the chamber and extending from one end of the body for penetrating a vein of the patient, valve means within the chamber shiftable to and from an open and closed condition permitting inflow of blood through the needle and a fluid outlet whereby said assembly is placed in communication with said receptacle to permit blood to be drawn through said assembly by the negative pressure exerted from the receptacle through the assembly.

Yet another object of the instant invention is the provision of a blood specimen collection assembly comprising a combination of components including check valve means within the body of the assembly, the check valve means having a ball adapted for a sealing the fluid inlet of the assembly against backflow and structure for spacing the ball from the fluid outlet during flow of blood through the assembly to the specimen receptacle.

A yet further object of the present invention is to provide a blood specimen collection assembly wherein the blood specimen is withdrawn from the patient into the specimen receptacle by means of a negative pressure exerted through the assembly by virtue of said receptacle being evacuated, the negative pressure causing shifting movement of a check valve to initially permit inflow of blood into the assembly and therethrough into the receptacle, the check valve then being permitted to shift to a closed position whereby to preclude backflow of the blood and testing mixture into the vein of the patient.

Other objects of this invention include many details of construction which will become apparent from following specification and accompanying drawing, wherein:

FIG. I is a fragmentary, elevational view partially in section and showing one form of the invention with a specimen receptacle and holder;

FIG. 2 is an enlarged, fragmentary, substantially central sectional view thereof with the receptacle and holder removed;

FIG. 3 is a sectional view taken along line 3 -3 of FIG. 2;

FIG. 4 is a side elevational view of another form of the invention with the specimen receptacle and holder removed;

FIG. 5 is an enlarged, fragmentary, substantially central sectional view of the assembly shown in FIG. 4; and

FIG. 6 is a sectional view taken along line 6 6 of FIG. 5.

The blood specimen collection assembly 10 as illustrated in the embodiment of the invention shown in FIG. 1 includes, as

its primary components, a body 12 having coupled therewith a specimen receptacle 14, there being a holder I6 provided for said receptacle in order that the assembly 10 may be utilized in the manner hereinafter described.

The body I2 is best illustrated in the sectional showing of FIG. 2 of the drawing, the same including a head 18 and a fitting 20, said head I8 and fitting 20 preferably being formed of compatible materials whereby the same may be fitted together in cooperating relationship whereby to define a chamber 22 therebetween, the forwardmost end of said chamber being defined by a conical sidewall 24 formed interiorly of head 18, the normally rearmost end of the chamber 22 being defined by a face 26 presented by an inner end of fitting 20.

A fluid inlet passage 28 extends through head 18 and is in communication with chamber 22, there being a hollow needle 30 carried within and extending substantially outwardly from said passage 28, which needle is penetrated into the vein of the patient during utilization of the assembly I0.

A fluid outlet passageway 32 is formed substantially centrally of fitting 20 and carries tubular member 34 which extends rearwardly or to the right of the assembly I0 viewing FIGS. 1 and 2.

In the embodiment of the invention illustrated in FIGS. 1- 3, the chamber 22 has check valve means disposed therein, said check valve means including a shiftable ball 36 and a plurality of ball-supporting flutes 38 formed as a part of the face 26 of fitting 20. Said check valve means permits longitudinal shifting movement of the ball 36 within the passage from the full line position shown in FIG. 2 of the drawing wherein the ball is in sealing engagement with the sidewall 24 whereby to close fluid inlet needle 30 to the dotted line position of FIG. 2 wherein the ball 36 is in engagement with the outer inclined edges 40 of the flutes 38, such engagement spacing ball 36 from the mouth 42 of tubular outlet member 34 whereby blood may pass through said outlet tube 34 and into the specimen receptacle when the assembly 10 is utilized in the manner hereinafter described.

In order to permit such utilization of the assembly 10 the same is normally coupled with specimen receptacle 14, which receptacle contains a predetermined amount of testing material in the nature of a suitable liquid or powder which is intended to react with the blood in a predeten'nined manner in order to indicate certain desired characteristics. It is important that the blood, when mixed with such testing material, not be permitted to flow back through assembly 10 and into the bloodstream of the patient whose blood is being tested. In order to achievethis result, a negative pressure is drawn on the receptacle l4 and the open end thereof is tightly closed by a stopper 44 having a centrally disposed thin section 46, to the opposite end of receptacle 14 being permanently sealed inasmuch as the same is in the nature of a test tube or the like.

In order to permit utilization of the assembly 10, the holder 16, which is tubular in nature, having an open right-hand end viewing FIG. 1 (not shown) is provided at its opposite end with a closure wall 48 having a central aperture 50 which is threaded to complementally engage the threads 52 carried exteriorly of fitting 20. Thus, holder 16 may be coupled with the assembly 10 by interengagement of the threads thereof and the receptacle 14 can then be telescoped into the holder 16, it

being noted that holder 16 could be provided with a pair of oppositely disposed finger-engaging flanges (not shown) whereby to permit the user of the complete assembly to easily grasp the holder 16 and exert, as by pressing thereupon with his thumb, a longitudinally directed force upon the receptacle 14. When such force is directed against the receptacle 14, the same, as it is being telescoped into the holder 16, will cause the central section 46 of stopper 44 to move into initial engagement with the sharpened end 54 of the tubular outlet member 34 whereby to cause end 54 to slightly penetrate section 46.

When the assembly has been prepared as by bringing the various components into the relative engagement hereinabove described, the patients arm is prepared as by placing a constricting band thereabout and a venipuncture is made below the band with the tip of needle 30. Receptacle 14 is then pushed further into the holder 16 thereby causing section 46 to be fully punctured by tubular member 34 and thereby place the evacuated receptacle 14 in communication with assembly through said member 34, chamber 22 and needle 30 and thus into communication with the vein of the patient. The evacuated nature of receptacle 14 causes the negative pressure therein to be created through the assembly 10 thereby shifting ball 36 from the full line to the dotted line position of FIG. 2, thence opening fluid inlet 56 of chamber 22 and permitting flow of blood through needle 30 into the chamber 22 and thence outwardly through mouth 42 into tubular member 34 and into the specimen receptacle 14 where it mixes with the testing material.

When receptacle [4 is sufficiently full of the blood specimen, the constricting band is released and the needle 30 removed from the vein of the patient, Release of the constricting band creates a negative pressure in the area above the band's former position and this pressure is transferred through the assembly 10. In the past, when collection devices of this nature were not provided with any check valve means, it was a simple matter to accidentally allow some of the blood and testing material mixture to be drawn back through the assembly and into the patient's bloodstream under the negative vein pressure, often resulting in serious illness or death. With the present invention, however, the negative pressure created by releasing the constricting band draws ball 36 toward wall 24 and thereby seals inlet 56, precluding backflow of the blood and testing material mixture into the vein of the patient.

The embodiment of the invention illustrated in FIGS. 46 of the drawing is generally similar in nature to that of F lGS. ll-

3 and is likewise adapted to be coupled with a specimen receptacle and holder, although the same are not shown in FIGS. 46.

Thus there is provided an assembly H0 having a body 112 comprised of a head 118 and a fitting 120, the same being coupled together whereby to cooperated to define a chamber 122,

the normally forwardmost portionof said chamber being defined by a conical sidewall 124 and the rearmost end of said chamber being defined by a face 126 of fitting 120. A passage 128 is provided through head 118 and receives a needle 130. Likewise, fitting has a central passage 132 therethrough which carries a tubular member 134.

Check valve means is disposed in the passage 122 and includes a shittable ball 136 which is movable between the full line and dotted line position of H0. 5. A coil spring I40 normally urges ball 136 toward sidewall 124 thereby closing the fluid inlet 156. When a negative pressure is exerted through the assembly 110 the'ball is caused to move from its dotted line position against spring 140 and toward the fluid outlet mouth 142, the ball being retained in a position spaced from said mouth by the spring 140, thereby permitting blood to flow through the assembly as by moving through needle 130, chamber 122 and tubular member 134 and thence into the specimen receptacle which has been suitably coupled with the assembly 110.

In either form of the invention the assembly safely and suffi ciently precludes any backflow of the blood and testing material into the blood stream of the patient inasmuch as the check valve means is positioned in the flow path ahead of the point of mixture of the blood with the testing material. Thus,

at any time that the constricting band about the patients arm is released, it will cause shifting movement of the ball to a closed, sealing condition thereby effectively and fully precluding the flow of any of the blood and testing material mixture back through the assembly from thespecimen receptacle 14 into the bloodstream of the patient.

lclaim:

l. A blood specimen collection assembly comprising:

a partially evacuated specimen receptacle;

a body having a chamber provided with a fluid inlet at one end and a fluid outlet at the opposite end, said chamber having a conical sidewall adjacent said fluid inlet and a plurality of radially spaced flutes adjacent said fluid outlet, surrounding said outlet and extending into said chamber;

a hollow needle extending from said one end of the body and in fluid eommunicationwith the chamber through said inlet;

a fitting closing said opposite end of the chamber and having said fluid outlet formed therein, said fluid outlet being in communication with said receptacle; and

check valve means in said chamber to permit flow of fluid through said chamber in one direction only, said check valve means including a ball larger in diameter than said fluid inlet and shiftable from a position in engagement with said conical wall whereby to close said fluid inlet and a position supported by said flutes in spaced relationship from said fluid outlet whereby to permit flow of fluid-

Claims (1)

1. A blood specimen collection assembly comprising: a partially evacuated specimen receptacle; a body having a chamber provided with a fluid inlet at one end and a fluid outlet at the opposite end, said chamber having a conical sidewall adjacent said fluid inlet and a plurality of radially spaced flutes adjacent said fluid outlet, surrounding said outlet and extending into said chamber; a hollow needle extending from said one end of the body and in fluid communication with the chamber through said inlet; a fitting closing said opposite end of the chamber and having said fluid outlet formed therein, said fluid outlet being in communication with said receptacle; and check valve means in said chamber to permit flow of fluid through said chamber in one direction only, said check valve means including a ball larger in diameter than said fluid inlet and shiftable from a position in engagement with said conical wall whereby to close said fluid inlet and a position supported by said flutes in spaced relationship from said fluid outlet whereby to permit flow of fluid through said chamber, out of said outlet and into said receptacle.
US3557778A 1968-11-18 1968-11-18 Blood specimen collection assembly Expired - Lifetime US3557778A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US77634768 true 1968-11-18 1968-11-18

Publications (1)

Publication Number Publication Date
US3557778A true US3557778A (en) 1971-01-26

Family

ID=25107134

Family Applications (1)

Application Number Title Priority Date Filing Date
US3557778A Expired - Lifetime US3557778A (en) 1968-11-18 1968-11-18 Blood specimen collection assembly

Country Status (1)

Country Link
US (1) US3557778A (en)

Cited By (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2332133A1 (en) * 1972-06-28 1974-01-10 Becton Dickinson Co Kanueleneinheit for taking blood samples
DE2332967A1 (en) * 1972-06-29 1974-01-10 Becton Dickinson Co A device for withdrawal of blood samples
US3848579A (en) * 1973-02-23 1974-11-19 Real A Villa Automatic elasto-valvular hypodermic sampling needle
US3881448A (en) * 1973-11-23 1975-05-06 Olof A Hallstrom Milking valve
US3916894A (en) * 1972-09-20 1975-11-04 Nosco Plastics Syringe seals and piston
FR2333521A1 (en) * 1975-12-03 1977-07-01 Burron Medical Prod Inc A device for administering a fluid parenterally
US4245635A (en) * 1979-01-29 1981-01-20 Jelco Laboratories Catheter assembly for intermittent intravenous use
FR2477403A1 (en) * 1980-03-10 1981-09-11 Becton Dickinson Co Assembly has multiple needles sampling comprising an anti-return valve
EP0051718A1 (en) * 1980-11-08 1982-05-19 Intermedicat Gmbh Entering device for catheters
US4333479A (en) * 1979-10-01 1982-06-08 Shiplee Iii Lewis D Disposable needle assembly
US4349035A (en) * 1978-03-14 1982-09-14 Johnson & Johnson Blood collection assembly with unidirectional flow valve
US4481008A (en) * 1981-10-08 1984-11-06 Bioresearch Inc. Apparatus and method for relieving excess negativity in a drainage device
FR2563990A1 (en) * 1984-05-10 1985-11-15 Labarthe Jean Instrument for taking small quantities of blood
US4732162A (en) * 1985-10-18 1988-03-22 Martell Medical Products, Inc. Automatic and position-sensitive syringe and method for nonaspirating or aspirating obtaining of blood samples
DE8703971U1 (en) * 1987-03-17 1988-07-21 Ballies, Uwe, Dr. Med., 2300 Kiel, De
US4857061A (en) * 1988-04-15 1989-08-15 Miller Michael D Single-flow valve-hypodermic needle combination
EP0335840A2 (en) * 1988-03-30 1989-10-04 Urbano Barbabella A gravity valve device to prevent liquids from draining completely out of vessels
WO1989010723A1 (en) * 1988-05-02 1989-11-16 Nielsen Bjoern A blood sampling equipment with needle, holder and vacuum vial
FR2636537A1 (en) * 1988-09-16 1990-03-23 Garde Claude Suction and withdrawal syringe
US4915688A (en) * 1987-12-03 1990-04-10 Baxter International Inc. Apparatus for administering solution to a patient
WO1990003777A1 (en) * 1988-10-14 1990-04-19 Corpak, Inc. Valve means for enteral therapy administration set
US4973248A (en) * 1988-12-09 1990-11-27 Myron International, Inc. Delivery system for dentinal/enamel adhesive materials
US5167238A (en) * 1991-05-02 1992-12-01 Cobe Laboratories, Inc. Fluid sampling device
US5309924A (en) * 1992-04-29 1994-05-10 Peabody Alan M Spill-proof blood collection device
FR2735373A1 (en) * 1995-06-16 1996-12-20 Debiotech Sa An angioplasty
WO1998007462A1 (en) * 1996-08-20 1998-02-26 Backes Claus H Medical high-pressure injection system
US5743883A (en) * 1995-06-07 1998-04-28 Visconti; Peter L. Thoracentesis catheter instruments having self-sealing valves
GB2327885A (en) * 1997-08-02 1999-02-10 Nmt Group Plc Filling needle
US6050957A (en) * 1998-07-01 2000-04-18 Desch; Larry W. Multiple-draw, variable suction syringe
US6217556B1 (en) 1998-03-19 2001-04-17 Allegiance Corporation Drainage catheter
US20020158083A1 (en) * 1991-12-06 2002-10-31 Brown Paul E. Dispensing valve
US20050101879A1 (en) * 2003-11-06 2005-05-12 Shidham Vinod B. Needle aspiration biopsy device and method
EP1614384A2 (en) * 2004-07-09 2006-01-11 Nipro Corporation Blood collection needle
US20060155213A1 (en) * 2005-01-10 2006-07-13 Madonia James R Self flushing luer activated blood sampling devices
US20090018174A1 (en) * 2005-11-08 2009-01-15 Pradip Kumar Bhatnagar Macrolides as anti-inflammatory agents
US20110190723A1 (en) * 2006-04-12 2011-08-04 Fangrow Thomas F Pressure-regulating vials and containers
US20110208128A1 (en) * 2010-02-24 2011-08-25 Becton, Dickinson And Company Safety Drug Delivery Connectors
US20110208160A1 (en) * 2010-02-24 2011-08-25 Becton, Dickinson And Company Safety Drug Delivery System
US8465461B2 (en) 2010-07-27 2013-06-18 Becton, Dickinson And Company Blunt needle safety drug delivery system
US20140074044A1 (en) * 2011-05-06 2014-03-13 Sanofi-Aventis Deutschland Gmbh Needle Hub and Valve for Needle Hub
US8968249B2 (en) 2002-05-10 2015-03-03 Covidien Lp Introducer seal assembly
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
CN104826178A (en) * 2010-03-12 2015-08-12 凯希特许有限公司 Reduced-pressure dressing connection pads, systems, and methods
US9107808B2 (en) 2007-03-09 2015-08-18 Icu Medical, Inc. Adaptors for removing medicinal fluids from a container
US9132062B2 (en) 2011-08-18 2015-09-15 Icu Medical, Inc. Pressure-regulating vial adaptors
US20150351728A1 (en) * 2013-01-09 2015-12-10 Floyd Nathan Stewart Urine sample device
CN105251115A (en) * 2015-10-21 2016-01-20 深圳市安特高科实业有限公司 Medical valve, medical communicating device and transfusion assembly
US9351905B2 (en) 2008-08-20 2016-05-31 Icu Medical, Inc. Anti-reflux vial adaptors
US9610217B2 (en) 2012-03-22 2017-04-04 Icu Medical, Inc. Pressure-regulating vial adaptors
US9615997B2 (en) 2013-01-23 2017-04-11 Icu Medical, Inc. Pressure-regulating vial adaptors
US9987195B2 (en) 2012-01-13 2018-06-05 Icu Medical, Inc. Pressure-regulating vial adaptors and methods

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1174745A (en) * 1915-03-11 1916-03-07 Lilly Co Eli Hypodermic syringe.
US1174673A (en) * 1915-09-10 1916-03-07 Lilly Co Eli Syringe.
US1363128A (en) * 1920-02-11 1920-12-21 Shigezo Nishitani Injection-syringe
US2102704A (en) * 1935-06-10 1937-12-21 George N Hein Syringe cartridge
US3123073A (en) * 1964-03-03 Blood sampling assembly
US3382865A (en) * 1965-10-18 1968-05-14 Ashton L. Worrall Jr. Device for taking multiple blood samples or the like

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123073A (en) * 1964-03-03 Blood sampling assembly
US1174745A (en) * 1915-03-11 1916-03-07 Lilly Co Eli Hypodermic syringe.
US1174673A (en) * 1915-09-10 1916-03-07 Lilly Co Eli Syringe.
US1363128A (en) * 1920-02-11 1920-12-21 Shigezo Nishitani Injection-syringe
US2102704A (en) * 1935-06-10 1937-12-21 George N Hein Syringe cartridge
US3382865A (en) * 1965-10-18 1968-05-14 Ashton L. Worrall Jr. Device for taking multiple blood samples or the like

Cited By (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2332133A1 (en) * 1972-06-28 1974-01-10 Becton Dickinson Co Kanueleneinheit for taking blood samples
DE2332967A1 (en) * 1972-06-29 1974-01-10 Becton Dickinson Co A device for withdrawal of blood samples
US3874367A (en) * 1972-06-29 1975-04-01 Becton Dickinson Co Valved blood sampling needle assembly
US3916894A (en) * 1972-09-20 1975-11-04 Nosco Plastics Syringe seals and piston
US3848579A (en) * 1973-02-23 1974-11-19 Real A Villa Automatic elasto-valvular hypodermic sampling needle
US3881448A (en) * 1973-11-23 1975-05-06 Olof A Hallstrom Milking valve
FR2333521A1 (en) * 1975-12-03 1977-07-01 Burron Medical Prod Inc A device for administering a fluid parenterally
US4349035A (en) * 1978-03-14 1982-09-14 Johnson & Johnson Blood collection assembly with unidirectional flow valve
US4245635A (en) * 1979-01-29 1981-01-20 Jelco Laboratories Catheter assembly for intermittent intravenous use
US4333479A (en) * 1979-10-01 1982-06-08 Shiplee Iii Lewis D Disposable needle assembly
FR2477403A1 (en) * 1980-03-10 1981-09-11 Becton Dickinson Co Assembly has multiple needles sampling comprising an anti-return valve
DE3103031A1 (en) * 1980-03-10 1981-12-17 Becton Dickinson Co A device for withdrawal of bodily fluids
US4317456A (en) * 1980-03-10 1982-03-02 Becton, Dickinson And Company Multiple sample needle with anti-backflow valve
EP0051718A1 (en) * 1980-11-08 1982-05-19 Intermedicat Gmbh Entering device for catheters
US4481008A (en) * 1981-10-08 1984-11-06 Bioresearch Inc. Apparatus and method for relieving excess negativity in a drainage device
FR2563990A1 (en) * 1984-05-10 1985-11-15 Labarthe Jean Instrument for taking small quantities of blood
US4732162A (en) * 1985-10-18 1988-03-22 Martell Medical Products, Inc. Automatic and position-sensitive syringe and method for nonaspirating or aspirating obtaining of blood samples
DE8703971U1 (en) * 1987-03-17 1988-07-21 Ballies, Uwe, Dr. Med., 2300 Kiel, De
US4915688A (en) * 1987-12-03 1990-04-10 Baxter International Inc. Apparatus for administering solution to a patient
EP0335840A2 (en) * 1988-03-30 1989-10-04 Urbano Barbabella A gravity valve device to prevent liquids from draining completely out of vessels
EP0335840A3 (en) * 1988-03-30 1990-01-31 Urbano Barbabella A gravity valve device to prevent liquids from draining completely out of vessels
US4857061A (en) * 1988-04-15 1989-08-15 Miller Michael D Single-flow valve-hypodermic needle combination
WO1989010723A1 (en) * 1988-05-02 1989-11-16 Nielsen Bjoern A blood sampling equipment with needle, holder and vacuum vial
FR2636537A1 (en) * 1988-09-16 1990-03-23 Garde Claude Suction and withdrawal syringe
WO1990003777A1 (en) * 1988-10-14 1990-04-19 Corpak, Inc. Valve means for enteral therapy administration set
US4973248A (en) * 1988-12-09 1990-11-27 Myron International, Inc. Delivery system for dentinal/enamel adhesive materials
US5167238A (en) * 1991-05-02 1992-12-01 Cobe Laboratories, Inc. Fluid sampling device
US5301686A (en) * 1991-05-02 1994-04-12 Cobe Laboratories, Inc. Fluid sampling method
US20020158083A1 (en) * 1991-12-06 2002-10-31 Brown Paul E. Dispensing valve
US5309924A (en) * 1992-04-29 1994-05-10 Peabody Alan M Spill-proof blood collection device
US5743883A (en) * 1995-06-07 1998-04-28 Visconti; Peter L. Thoracentesis catheter instruments having self-sealing valves
WO1997000093A1 (en) * 1995-06-16 1997-01-03 Debiotech S.A. Angioplasty device
FR2735373A1 (en) * 1995-06-16 1996-12-20 Debiotech Sa An angioplasty
WO1998007462A1 (en) * 1996-08-20 1998-02-26 Backes Claus H Medical high-pressure injection system
GB2327885A (en) * 1997-08-02 1999-02-10 Nmt Group Plc Filling needle
US6217556B1 (en) 1998-03-19 2001-04-17 Allegiance Corporation Drainage catheter
US6050957A (en) * 1998-07-01 2000-04-18 Desch; Larry W. Multiple-draw, variable suction syringe
US8968249B2 (en) 2002-05-10 2015-03-03 Covidien Lp Introducer seal assembly
US20050101879A1 (en) * 2003-11-06 2005-05-12 Shidham Vinod B. Needle aspiration biopsy device and method
EP1614384A2 (en) * 2004-07-09 2006-01-11 Nipro Corporation Blood collection needle
EP1614384A3 (en) * 2004-07-09 2006-03-22 Nipro Corporation Blood collection needle
US20060009714A1 (en) * 2004-07-09 2006-01-12 Yoshio Higaki Blood collection needle
US7267653B2 (en) 2004-07-09 2007-09-11 Nipro Corporation Blood collection needle
CN100518642C (en) 2004-07-09 2009-07-29 尼普洛株式会社 Blood collection needle
US20080064985A1 (en) * 2005-01-10 2008-03-13 Madonia James R Self flushing luer activated blood sampling devices
US7314452B2 (en) * 2005-01-10 2008-01-01 Edwards Lifesciences Corporation Self flushing luer activated blood sampling devices
US7963950B2 (en) 2005-01-10 2011-06-21 Edwards Lifesciences Corporation Self flushing luer activated blood sampling devices
US20060155213A1 (en) * 2005-01-10 2006-07-13 Madonia James R Self flushing luer activated blood sampling devices
US20090018174A1 (en) * 2005-11-08 2009-01-15 Pradip Kumar Bhatnagar Macrolides as anti-inflammatory agents
US9072657B2 (en) 2006-04-12 2015-07-07 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US10071020B2 (en) 2006-04-12 2018-09-11 Icu Medical, Inc. Devices for transferring fluid to or from a vial
US9662272B2 (en) 2006-04-12 2017-05-30 Icu Medical, Inc. Devices and methods for transferring fluid to or from a vial
US9993391B2 (en) 2006-04-12 2018-06-12 Icu Medical, Inc. Devices and methods for transferring medicinal fluid to or from a container
US10022302B2 (en) 2006-04-12 2018-07-17 Icu Medical, Inc. Devices for transferring medicinal fluids to or from a container
US8992501B2 (en) 2006-04-12 2015-03-31 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US8882738B2 (en) 2006-04-12 2014-11-11 Icu Medical, Inc. Locking vial adaptors and methods
US8945084B2 (en) 2006-04-12 2015-02-03 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US20110190723A1 (en) * 2006-04-12 2011-08-04 Fangrow Thomas F Pressure-regulating vials and containers
US8974433B2 (en) 2006-04-12 2015-03-10 Icu Medical, Inc. Pressure-regulating vials and containers
US9993390B2 (en) 2006-04-12 2018-06-12 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US9005180B2 (en) 2006-04-12 2015-04-14 Icu Medical, Inc. Vial adaptors and methods for regulating pressure
US9005179B2 (en) 2006-04-12 2015-04-14 Icu Medical, Inc. Pressure-regulating apparatus for withdrawing medicinal fluid from a vial
US9060921B2 (en) 2006-04-12 2015-06-23 Icu Medical, Inc. Air-filtering vial adaptors and methods
US9107808B2 (en) 2007-03-09 2015-08-18 Icu Medical, Inc. Adaptors for removing medicinal fluids from a container
US9931275B2 (en) 2008-08-20 2018-04-03 Icu Medical, Inc. Anti-reflux vial adaptors
US9351905B2 (en) 2008-08-20 2016-05-31 Icu Medical, Inc. Anti-reflux vial adaptors
US9056163B2 (en) 2010-02-24 2015-06-16 Becton, Dickinson And Company Safety drug delivery system
US20110208160A1 (en) * 2010-02-24 2011-08-25 Becton, Dickinson And Company Safety Drug Delivery System
CN102844073A (en) * 2010-02-24 2012-12-26 贝克顿·迪金森公司 Safety drug delivery connectors
WO2011106374A1 (en) * 2010-02-24 2011-09-01 Becton, Dickinson And Company Safety drug delivery connectors
US20110208128A1 (en) * 2010-02-24 2011-08-25 Becton, Dickinson And Company Safety Drug Delivery Connectors
CN102844073B (en) * 2010-02-24 2015-11-25 贝克顿·迪金森公司 A drug delivery connector
US9205248B2 (en) * 2010-02-24 2015-12-08 Becton, Dickinson And Company Safety Drug delivery connectors
US9381339B2 (en) 2010-02-24 2016-07-05 Becton, Dickinson And Company Safety drug delivery connectors
CN104826178A (en) * 2010-03-12 2015-08-12 凯希特许有限公司 Reduced-pressure dressing connection pads, systems, and methods
US9427502B2 (en) 2010-03-12 2016-08-30 Kci Licensing, Inc. Reduced-pressure dressing connection pads, systems, and methods
EP2921199A1 (en) * 2010-03-12 2015-09-23 KCI Licensing Inc. Reduced-pressure dressing connection pads, systems, and methods
CN104826178B (en) * 2010-03-12 2018-05-04 凯希特许有限公司 Reduced pressure dressing connection pad, systems and methods
US8465461B2 (en) 2010-07-27 2013-06-18 Becton, Dickinson And Company Blunt needle safety drug delivery system
US9044554B2 (en) 2010-07-27 2015-06-02 Becton, Dickinson And Company Blunt needle safety drug delivery system
US20140074044A1 (en) * 2011-05-06 2014-03-13 Sanofi-Aventis Deutschland Gmbh Needle Hub and Valve for Needle Hub
US9345845B2 (en) * 2011-05-06 2016-05-24 Sanofi-Aventis Deutschland Gmbh Needle hub and valve for needle hub
US9895291B2 (en) 2011-08-18 2018-02-20 Icu Medical, Inc. Pressure-regulating vial adaptors
US9132062B2 (en) 2011-08-18 2015-09-15 Icu Medical, Inc. Pressure-regulating vial adaptors
US9987195B2 (en) 2012-01-13 2018-06-05 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US9610217B2 (en) 2012-03-22 2017-04-04 Icu Medical, Inc. Pressure-regulating vial adaptors
US20150351728A1 (en) * 2013-01-09 2015-12-10 Floyd Nathan Stewart Urine sample device
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
US9615997B2 (en) 2013-01-23 2017-04-11 Icu Medical, Inc. Pressure-regulating vial adaptors
US9763855B2 (en) 2013-01-23 2017-09-19 Icu Medical, Inc. Pressure-regulating vial adaptors
CN105251115A (en) * 2015-10-21 2016-01-20 深圳市安特高科实业有限公司 Medical valve, medical communicating device and transfusion assembly

Similar Documents

Publication Publication Date Title
US3306290A (en) Automatically retractable needle syringe
US3322126A (en) Endotracheal catheter
US3336924A (en) Two compartment syringe package
US3373735A (en) Medical-surgical tube
US3557787A (en) Disposable syringe
US3319622A (en) Device for gastro-intestinal fluids
US3532094A (en) Cryogenic-instrument with detachable probe
US3696806A (en) Apparatus for taking samples of liquid
US3037619A (en) Suture devices
US3181529A (en) Valved body-fluid sampling tubes
US3513830A (en) Instrument for obtaining body cultures
US3620216A (en) Implant trocar
US3063451A (en) Self-venting type needle
US3037496A (en) Fertility testing apparatus
US6585690B1 (en) Hypodermic syringe with selectivity retractable needle
US2876770A (en) Shielded hypodermic syringe
US3394699A (en) Instrument for obtaining a biopsy specimen
US4312950A (en) Disposable swab and culture unit
US3863624A (en) Vacuum curettage device
US5769826A (en) Spring loaded retractable cannula blood drawing device
US5662127A (en) Self-contained blood withdrawal apparatus and method
US4465200A (en) Low contamination closure for blood collection tubes
US4160450A (en) Outside-the-needle catheter device with needle housing
US3826261A (en) Vial and syringe assembly
US5147329A (en) Intravenous access devices