US3123073A - Blood sampling assembly - Google Patents

Blood sampling assembly Download PDF

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US3123073A
US3123073A US3123073DA US3123073A US 3123073 A US3123073 A US 3123073A US 3123073D A US3123073D A US 3123073DA US 3123073 A US3123073 A US 3123073A
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cannula
stopper
vial
end
assembly
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150267Modular design or construction, i.e. subunits are assembled separately before being joined together or the device comprises interchangeable or detachable modules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150488Details of construction of shaft
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150496Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/15058Joining techniques used for protective means
    • A61B5/150587Joining techniques used for protective means by friction fit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150694Procedure for removing protection means at the time of piercing
    • A61B5/150717Procedure for removing protection means at the time of piercing manually removed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means

Description

March 3, 1964 c. H. BARR, sR., ETAL 3,123,073

BLOOD SAMPLING ASSEMBLY Filed Aug. 26, 1958 2 Sheets-Sheet 1 coae/zfi/vo A. 5024?, .52. ma mas/0 e ee, JQ. t 2 JOHN m. 5022 INVENTORS BY iwmjpyfi March 3, 1964 c. H. BARR, SR., ETAL 3,123,073

- BLOOD SAMPLING ASSEMBLY Filed Aug. 26, 1958 2 Sheets-Sheet 2 60087'4/7/8/0 H. 5022, ue.

JOHN 4a 5/722 INVENTORS United States Patent 3,123,073 BLOOD SAMPLING ASEWLY Courtland H. Barr, Sn, Courtland H. Barr, In, and John W. Barr, all Courtland Laboratories, 5555 Valley Blvd, Los Angeles 32, Calif.

Filed Aug. 26, 1258, Ser. No. 757,308 11 Claims. (Cl. 128-276) This invention relates to apparatus for the collection of blood samples and has particular reference to improved apparatus used in drawing or otherwise collecting blood from veins.

Our copending application Serial No. 537,978 filed October 3, 1955 discloses a novel blood sampling assembly designed to overcome many disadvantages of the assemblies theretofore proposed and used. A primary object of the present invention is to provide improvements in the basic structure disclosed in said copending application.

Another object of the present invention is to provide a disposable blood sampling assembly comprising a stoppered evacuated vial and a canula operably connected thereto, the assembly including novel means for connecting the cannula to the vial.

Another object of the present invention is to provide blood sampling assembly including novel means for preventing premature piercing of the vial stopper by the cannula.

Other objects and advantages of the present invention it is believed will be readily apparent from the following detailed description of preferred embodiments thereof when read in connection with the accompanying drawings.

In the drawings:

FIGURE 1 is a perspective View of a blood sampling assembly embodying the present invention.

FIGURE 2 is a sectional elevation taken substantially on the line 2-2 of FIGURE 1.

FIGURE 3 is a sectional view taken substantially on the line 3-3 of FIGURE 2.

FIGURE 4 is a vertical sectional view of a modified form of the invention.

FIGURE 5 is a fragmentary side elevation, partly in section, illustrating a further modified form of the invention.

FIGURE 6 is a sectional view taken substantially on the line 66 of FIGURE 5.

FIGURE 7 is a fragmentary side elevation, partly in section, illustrating another modified form of the invention.

FIGURE 8 is a sectional view taken substantially on the line 88 of FIGURE 7.

FIGURE 9 is a perspective view of still another modified form of the invention.

FIGURE 10 is a sectional elevation taken substantially on the line 1fl10 of FIGURE 9.

FIGURE 11 is a sectional view taken substantially on the line 11-11 of FIGURE 10.

Referring now to the drawings, one embodiment of the present invention is illustrated in FIGURES 1-3. The blood sampling assembly shown therein includes a tube or vial 20, preferably of glass, having a closed bottom end 21, the top of the open end 22 being closed by a stopper 24.

The stopper 24 is made of rubber or rubber-like material of suitable composition and has a flanged head portion 25 overlying the end of the vial 2%). Integral with the head portion is a body portion 26 which extends into the open end of the vial, the diameter of the body portion being somewhat larger than the inside diameter of the vial so that the body portion is under compression when inserted into the assembled position shown. The lower end of the body portion is bevelled as at 30 to facilitate assembly of the stopper and the vial.

As shown best in FIGURE 2, the bottom surface 31 of the stopper body portion is substantially planm and is imperforate, having no recess therein as is the case with conventional stoppers utilized in such apparatus. The head portion of the stopper is provided with a generally cylindrical central recess 33 extending downwardly from the top thereof a substantial distance into the body portion, a diaphragm 34 being thus defined.

The assembly also includes a cannula 35 having sharpened, bevelled ends 36 and 37. The cannula extends centrally through and is secured to a hub member 38 which is provided at one end with a tapered portion 3? merging into a cylindrical portion 44). The other end of the hub member is provided with a flange 41 and a fluted cylindrical portion 42. Intermediate the cylindrical portions and 42 is a circumferential tapered groove 43.

Means are provided for operably connecting the cannula to the vial and as shown in FIGURES 13, these means include a cannula holder 45. The holder 4-5 is preferably molded of plastic and includes a central body portion 46 having lateral extension portions 46:: and a central bore 47 into which the hub member 38 is driven, the flange 41, the fluted portion 42 and the shoulders formed by the groove 43 serving to hold the hub member and its cannula firmly in position, yet permitting quick and easy assembly of the parts. Finger grip means are also included on the holder and as shown these means include a pair of parallel leg portions 59 and 51, one on either side of the vial and provided at the ends thereof with an interconnection comprising a disk-like finger grip member 52 having a central opening 53 therein for the vial.

The flanged head portion 25 of the stopper is provided with a pair of diametrically opposed notched portions 55 slightly narrower than the width of the leg portions 56 and 51 so that the leg portions are frictionally engaged by the rubber stopper flange. It is this frictional engagement, plus the partial piercing of the diaphragm 34 by the cannula end 37, which connects the cannula and its associated parts to the vial and thus completes a unitary assembly.

The assembly described above is ready for immediate use merely by removal of the customary cannula cover member illustrated in phantom lines in FIGURE 2. The end 36 of the cannula is then inserted into the vein of the subject and thereupon the finger grip member 52 is grasped with two fingers and the thumb is held over the end of the vial. Thus the assembly may be operated in the manner of a syringe by pushing the thumb toward the fingers, whereupon the cannula end 37 pierces through the diaphragm 34 to establish communication with the evacuated interior of the vial, the differential in pressure causing a blood sample to be drawn into the vial through the cannula.

A modified form of the invention is illustrated in FIGURE 4. This assembly includes an evacuated vial 2th; having a stopper 24a substantially the same as the stopper 24.

The cannula holder 60 comprises a central, tapered body portion 51 having a flange 62, and integral therewith is a pair of leg members 63 connected at the other ends by means of a disk-like finger grip member 64 which is similar to that described above, but which has a central opening, defined by an annular flash 65 or thin portion of the grip member, smaller in diameter than the vial so as to frictionally grip the vial. Integral with the body portion 61 is a spike element 66 extending into the stopper recess and adapted to pierce the diaphragm 34a. The spike element is provided with a central opening 67 adapted to communicate with the cannula 68 which is provided with a tapered, cup-shaped hub member 69 driven onto the body portion.

A cannula cover member 76 completes the assembly, the operation of which is the same as that of the assembly of FIGURES 1-3.

A further modified form of the invention is illustrated in FIGURES and 6. This assembly is substantially the same as that of FIGURES 13, being provided with a vial 29b, a stopper 245, a cannula b and a cannula holder b. I-lere however, means are provided for preventing accidental piercing of the stopper with the cannula, such as might be occasioned by rough handling of the assembly. As shown in FIGURES 5 and 6, these means may include a pair of severable spacer members 80 and 81, one secured to each of the leg members and 51b and extending between the top of the stopper and the underside of the lateral extension portions 466 The spacer members are formed integral with the leg members but are each provided with a groove 82 at the line of connection so as to be easily severed from the leg members immediately prior to use of the assembly. Until such severance is accomplished however, it will be understood that the spacer members prevent any longitudinal movement of the cannula and cannula holder in a direction toward the stopper and thus guard against accidental or premature piercing of the stopper with the resultant loss of vacuum and inoperability of the assem bly.

The modified structure of FIGURES 7 and 8 is similar to that of FIGURES 5 and 6 except that here the spacer members 86 and 87 are not integral with the leg members 5th: and 51c, but are generally C-shaped members adapted to be resiliently clamped onto the leg members, and to be readily removed therefrom for use of the device.

A further modified form of the invention is illustrated in FIGURES 9, l0 and 11. This device also includes an evacuated vial Ztld, a stopper 24d, a cannula 35d and a cannula holder 45d, generally similar to those same elements shown in FIGURES 1-3. Here, however, the stopper flange 25d is not notched, but is merely permitted to be deformed or bent in those portions thereof which contact the leg portions 50d and 51d, thus providing a similar frictional engagement. The stopper recess 33d also difiers from the recess 33 in that it is tapered and closely fits around the cannula to provide a further gripping connection between the cannula and the vial.

Means are also provided for preventing accidental piercing of the stopper, and as shown in FIGURES 9 l1, these means include a pair of spacer members 90 and 91 extending downwardly from the cannula cover member 92, the ends of the spacer members contracting the upper surface of the stopper.

It will be understood to those skilled in the art that while the improvements constituting the present invention have been described in connection with a blood sampling assembly the use thereof is not inherently so limited and these improvements may be incorporated on other structures such as, for example, disposable assemblies for administering injectables.

Having fully described our invention, it is to be understood that we do not wish to be limited to the details set forth, but our invention is of the full scope of the appended claims.

We claim:

1. A cannula and vial assembly comprising the combination of a vial rigidly closed at one end by an integrally united member and closed at the other end with a stopper of resilient material, a cannula, and means operably connecting said cannula to said vial with one end of said cannula inserted in said stopper, said means incluch'ng a cannula holder to which said cannula is secured, said holder including a pair of leg portions contacting portions of said stopper in friction fit relationship therewith, the end of the vial remote from said stopper extending beyond the ends of said leg portions, said assembly including rigid means for preventing piercing of said stopper by said cannula by forces tending to move said cannula toward said stopper.

2. The combination of claim 1, wherein said rigid means comprises a removable spacer element inserted between the stopper and said cannula holder.

3. The combination of claim 1, including a cannula cover member and wherein said rigid means comprises a spacer element carried on said cover member and contacting said stopper.

4. A cannula and vial assembly, comprising the combi nation of a vial rigidly closed at one end by an integrally united member and closed at the other end with a stopper of resilient material, said stopper having a central recess extending downwardly from the top thereof to form a diaphragm in said stopper, a cannula, and means operably connecting said cannula to said vial with one end of said cannula inserted in said central recess, said 7 means including a cannula holder to which said cannula is secured, said holder including a pair of leg portions contacting portions of said stopper in friction fit relationship therewith and a finger-grip member securing together the ends of said leg portions, the end of the vial remote from said stopper extending beyond the ends of said leg portions, said assembly including rigid means for preventing piercing of said diaphragm by said cannula by forces tending to move said cannula toward said diaphragm.

5. The combination of claim 4 wherein said rigid means comprises a removable spacer element inserted between the stopper and said cannula holder.

6. A cannula and vial assembly comprising the combination of a vial rigidly closed at one end by an integrally united member and closed at the other end with a stopper of resilient material, said stopper having a central recess extending downwardly from the top thereof to form a diaphragm in said stopper, a cannula, and means operably connecting said cannula to said vial with one end of said cannula inserted in said central recess, said means including a cannula holder to which said cannula is secured, said holder including a pair of leg portions and a finger-grip member securing together the ends of said leg portions, the end of the vial remote from said stopper extending beyond the ends of said leg portions, said finger-grip members having a portion forming a central opening through which said vial extends in friction fit relationship with said portion, said assembly including rigid means for preventing piercing of said diaphragm by said cannula by forces tending to move said cannula toward said diaphragm.

7. The combination of claim 6, wherein said rigid means comprises a removable spacer element inserted between the stopper and said cannula-holder.

8. The combination of claim 1, wherein the central recess is tapered and fits closely upon the cannula.

9. The combination of claim 1 wherein the vial is evacuated.

10. The combination of claim 4 wherein the vial is evacuated.

5 6 11. The combination of claim 6 wherein the vial is 2,676,591 FOX Apr. 27, 1954 evacuated. 2,737,949 BI'OWH Mar. 13, 1956 2,841,143 Bertram July 1, 1958 Refea'ences Cited in the file of this patent 2,845,067 Gabriel July 29, 1958 U TED STATES PATENTS 5 2,889,723 Adams p 1959 2,437,408 Scet Mar. 9, 1948 FOREEGN PATENTS 2,460,641 Kleiner Feb. 1, 1949 115,391 Austria Dec. 10, 1929

Claims (1)

1. A CANNULA AND VIAL ASSEMBLY COMPRISING THE COMBINATION OF A VIAL RIGIDLY CLOSED AT ONE END BY AN INTEGRALLY UNITED MEMBER AND CLOSED AT THE OTHER END WITH A STOPPER OF RESILIENT MATERIAL, A CANNULA, AND MEANS OPERABLY CONNECTING SAID CANNULA TO SAID VIAL WITH ONE END OF SAID CANNULA INSERTED IN SAID STOPPER, SAID MEANS INCLUDING A CANNULA HOLDER TO WHICH SAID CANNULA IS SECURED, SAID HOLDER INCLUDING A PAIR OF LEG PORTIONS CONTACTING PORTIONS OF SAID STOPPER IN FRICTION FIT RELATIONSHIP THEREWITH, THE END OF THE VIAL REMOTE FROM SAID STOPPER EXTENDING BEYOND THE ENDS OF SAID LEG PORTIONS, SAID ASSEMBLY INCLUDING RIGID MEANS FOR PREVENTING PIERCING OF SAID STOPPER BY SAID CANNULA BY FORCES TENDING TO MOVE SAID CANNULA TOWARD SAID STOPPER.
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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3395696A (en) * 1965-06-22 1968-08-06 Roehr Products Inc Physiological fluid transfer apparatus
US3405706A (en) * 1965-04-22 1968-10-15 Cinqualbre Paul Arrangement for taking blood
US3494351A (en) * 1966-06-21 1970-02-10 Ferrell S Horn Multiple vial fluid collecting device
US3557778A (en) * 1968-11-18 1971-01-26 Elbert L Hughes Blood specimen collection assembly
US3916894A (en) * 1972-09-20 1975-11-04 Nosco Plastics Syringe seals and piston
US3974832A (en) * 1975-01-07 1976-08-17 Vca Corporation Interchangeable hypodermic needle assemblage
WO1979001131A1 (en) * 1978-05-26 1979-12-27 R Turner Liquid sample collector device
US4781700A (en) * 1986-06-17 1988-11-01 Finbiomedica S.R.L. Device for taking from a vein samples of blood to be tested
US4819659A (en) * 1987-09-21 1989-04-11 Icu Medical, Inc. Blood withdrawal device with movable needle guard member
EP0472023A1 (en) * 1990-08-22 1992-02-26 Becton Dickinson and Company Assembly for aspirating tissue, including adapter for syringe
US5800395A (en) * 1996-12-05 1998-09-01 Mdc Investment Holdings, Inc. Medical device with retractable needle
US6004278A (en) * 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
EP1188456A1 (en) * 2000-09-14 2002-03-20 Terumo Kabushiki Kaisha Injection needle and injection apparatus
US20040025556A1 (en) * 2001-03-23 2004-02-12 Klint Henrik Sonderskov Needle cannula, a method of producing a needle cannula and use of a needle cannula

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2437408A (en) * 1946-07-25 1948-03-09 John C Soet Blood drawing instrument
US2460641A (en) * 1945-08-14 1949-02-01 Joseph J Kleiner Blood collecting apparatus
US2676591A (en) * 1951-03-27 1954-04-27 Fox Dorothy Brown Hypodermic unit
US2737949A (en) * 1952-01-04 1956-03-13 Pfizer & Co C Disposable cartridge for hypodermic syringe
US2841143A (en) * 1956-01-17 1958-07-01 Penicillin Ges Dauelsberg & Co Injection device for liquids and ampoule therefor
US2845067A (en) * 1955-07-01 1958-07-29 Gabriel Daniel Vials containing medication under pressure
US2880723A (en) * 1954-02-09 1959-04-07 Becton Dickinson Co Syringe assembly

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2460641A (en) * 1945-08-14 1949-02-01 Joseph J Kleiner Blood collecting apparatus
US2437408A (en) * 1946-07-25 1948-03-09 John C Soet Blood drawing instrument
US2676591A (en) * 1951-03-27 1954-04-27 Fox Dorothy Brown Hypodermic unit
US2737949A (en) * 1952-01-04 1956-03-13 Pfizer & Co C Disposable cartridge for hypodermic syringe
US2880723A (en) * 1954-02-09 1959-04-07 Becton Dickinson Co Syringe assembly
US2845067A (en) * 1955-07-01 1958-07-29 Gabriel Daniel Vials containing medication under pressure
US2841143A (en) * 1956-01-17 1958-07-01 Penicillin Ges Dauelsberg & Co Injection device for liquids and ampoule therefor

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3405706A (en) * 1965-04-22 1968-10-15 Cinqualbre Paul Arrangement for taking blood
US3395696A (en) * 1965-06-22 1968-08-06 Roehr Products Inc Physiological fluid transfer apparatus
US3494351A (en) * 1966-06-21 1970-02-10 Ferrell S Horn Multiple vial fluid collecting device
US3557778A (en) * 1968-11-18 1971-01-26 Elbert L Hughes Blood specimen collection assembly
US3916894A (en) * 1972-09-20 1975-11-04 Nosco Plastics Syringe seals and piston
US3974832A (en) * 1975-01-07 1976-08-17 Vca Corporation Interchangeable hypodermic needle assemblage
WO1979001131A1 (en) * 1978-05-26 1979-12-27 R Turner Liquid sample collector device
US4781700A (en) * 1986-06-17 1988-11-01 Finbiomedica S.R.L. Device for taking from a vein samples of blood to be tested
US4819659A (en) * 1987-09-21 1989-04-11 Icu Medical, Inc. Blood withdrawal device with movable needle guard member
EP0472023A1 (en) * 1990-08-22 1992-02-26 Becton Dickinson and Company Assembly for aspirating tissue, including adapter for syringe
US6436070B1 (en) 1996-12-05 2002-08-20 Mdc Investment Holdings, Inc. Catheter insertion device with retractable needle
US6004278A (en) * 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
US5800395A (en) * 1996-12-05 1998-09-01 Mdc Investment Holdings, Inc. Medical device with retractable needle
US20020052580A1 (en) * 2000-09-14 2002-05-02 Tetsuya Ooyauchi Injection needle and injection apparatus
EP1188456A1 (en) * 2000-09-14 2002-03-20 Terumo Kabushiki Kaisha Injection needle and injection apparatus
US6843783B2 (en) 2000-09-14 2005-01-18 Terumo Kabushiki Kaisha Injection needle and injection apparatus
US20050096603A1 (en) * 2000-09-14 2005-05-05 Terumo Kabushiki Kaisha Injection needle and injection apparatus
US7632253B2 (en) 2000-09-14 2009-12-15 Terumo Kabushiki Kaisha Injection needle and injection apparatus
US20040025556A1 (en) * 2001-03-23 2004-02-12 Klint Henrik Sonderskov Needle cannula, a method of producing a needle cannula and use of a needle cannula
US20040064109A1 (en) * 2001-03-23 2004-04-01 Klint Henrik Sonderskov Needle cannula, a method of producing a needle cannula and use of a needle cannula
US20060247583A1 (en) * 2001-03-23 2006-11-02 Novo Nordisk A/S Tapered pen syringe needle

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