JP7266519B2 - 時間分解蛍光分光法のためのシステム、デバイス、および方法 - Google Patents

時間分解蛍光分光法のためのシステム、デバイス、および方法 Download PDF

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JP7266519B2
JP7266519B2 JP2019502534A JP2019502534A JP7266519B2 JP 7266519 B2 JP7266519 B2 JP 7266519B2 JP 2019502534 A JP2019502534 A JP 2019502534A JP 2019502534 A JP2019502534 A JP 2019502534A JP 7266519 B2 JP7266519 B2 JP 7266519B2
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optical
tissue
signal
biological sample
spectral bands
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ピラモド ビュート，
キース ブラック，
ジャック カバノー，
バルトシュ ボルトニック，
ジャオジュン ニエ，
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ブラック ライト サージカル， インコーポレイテッド
セダーズ－シナイ メディカル センター
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
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    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
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    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
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    • G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
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    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
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    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
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    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
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    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
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    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
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    • G01J2003/1265—Generating the spectrum; Monochromators the wavelengths being separated in time, e.g. through optical fibre array
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  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Laser Surgery Devices (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
JP2019502534A 2016-04-01 2017-03-31 時間分解蛍光分光法のためのシステム、デバイス、および方法 Active JP7266519B2 (ja)

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JP2022166130A JP7671725B2 (ja) 2016-04-01 2022-10-17 時間分解蛍光分光法のためのシステム、デバイス、および方法
JP2025016015A JP2025065221A (ja) 2016-04-01 2025-02-03 時間分解蛍光分光法のためのシステム、デバイス、および方法

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US201662317452P 2016-04-01 2016-04-01
US201662317451P 2016-04-01 2016-04-01
US201662317460P 2016-04-01 2016-04-01
US201662317455P 2016-04-01 2016-04-01
US201662317443P 2016-04-01 2016-04-01
US201662317456P 2016-04-01 2016-04-01
US201662317459P 2016-04-01 2016-04-01
US201662317453P 2016-04-01 2016-04-01
US201662317449P 2016-04-01 2016-04-01
US62/317,455 2016-04-01
US62/317,456 2016-04-01
US62/317,443 2016-04-01
US62/317,453 2016-04-01
US62/317,451 2016-04-01
US62/317,460 2016-04-01
US62/317,459 2016-04-01
US62/317,449 2016-04-01
US62/317,452 2016-04-01
US201662351615P 2016-06-17 2016-06-17
US62/351,615 2016-06-17
PCT/US2017/025451 WO2017173315A1 (en) 2016-04-01 2017-03-31 Systems, devices, and methods for time-resolved fluorescent spectroscopy

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JP2025016015A Pending JP2025065221A (ja) 2016-04-01 2025-02-03 時間分解蛍光分光法のためのシステム、デバイス、および方法

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