JP7259182B2 - in situ分子検出のためのハイブリダイゼーション連鎖反応法 - Google Patents
in situ分子検出のためのハイブリダイゼーション連鎖反応法 Download PDFInfo
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- C12Q1/6841—In situ hybridisation
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
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- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326959P | 2016-04-25 | 2016-04-25 | |
| US62/326,959 | 2016-04-25 | ||
| PCT/US2017/029333 WO2017189525A1 (en) | 2016-04-25 | 2017-04-25 | Hybridization chain reaction methods for in situ molecular detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019518434A JP2019518434A (ja) | 2019-07-04 |
| JP2019518434A5 JP2019518434A5 (enExample) | 2020-06-18 |
| JP7259182B2 true JP7259182B2 (ja) | 2023-04-18 |
Family
ID=60160064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555974A Active JP7259182B2 (ja) | 2016-04-25 | 2017-04-25 | in situ分子検出のためのハイブリダイゼーション連鎖反応法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11718874B2 (enExample) |
| EP (2) | EP4613756A3 (enExample) |
| JP (1) | JP7259182B2 (enExample) |
| CN (2) | CN109415761B (enExample) |
| AU (2) | AU2017257624B2 (enExample) |
| CA (2) | CA3210120C (enExample) |
| WO (1) | WO2017189525A1 (enExample) |
Families Citing this family (128)
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| EP2766498B1 (en) | 2011-10-14 | 2019-06-19 | President and Fellows of Harvard College | Sequencing by structure assembly |
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| US10138509B2 (en) | 2013-03-12 | 2018-11-27 | President And Fellows Of Harvard College | Method for generating a three-dimensional nucleic acid containing matrix |
| WO2016007839A1 (en) | 2014-07-11 | 2016-01-14 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| EP4273263A3 (en) | 2014-07-30 | 2024-01-31 | President and Fellows of Harvard College | Systems and methods for determining nucleic acids |
| EP4321627A3 (en) | 2015-04-10 | 2024-04-17 | 10x Genomics Sweden AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| CN108474022A (zh) | 2015-11-03 | 2018-08-31 | 哈佛学院董事及会员团体 | 用于包含三维核酸的基质容积成像的设备和方法 |
| AU2017257624B2 (en) | 2016-04-25 | 2023-05-25 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| US11352667B2 (en) | 2016-06-21 | 2022-06-07 | 10X Genomics, Inc. | Nucleic acid sequencing |
| ES2908919T3 (es) | 2016-07-05 | 2022-05-04 | California Inst Of Techn | Reacción en cadena de hibridación de iniciador fraccionario |
| GB2569252A (en) | 2016-08-31 | 2019-06-12 | Harvard College | Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing |
| WO2019068880A1 (en) | 2017-10-06 | 2019-04-11 | Cartana Ab | RNA MATRIX LIGATION |
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