JP7212624B2 - 低下した粘度を有する高タンパク酸性液体乳製品、それを製造する方法及び関連する成分 - Google Patents
低下した粘度を有する高タンパク酸性液体乳製品、それを製造する方法及び関連する成分 Download PDFInfo
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- JP7212624B2 JP7212624B2 JP2019544074A JP2019544074A JP7212624B2 JP 7212624 B2 JP7212624 B2 JP 7212624B2 JP 2019544074 A JP2019544074 A JP 2019544074A JP 2019544074 A JP2019544074 A JP 2019544074A JP 7212624 B2 JP7212624 B2 JP 7212624B2
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| JP2023017803A (ja) * | 2017-02-17 | 2023-02-07 | アーラ フーズ エエムビエ | 低下した粘度を有する高タンパク酸性液体乳製品、それを製造する方法及び関連する成分 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3104750A1 (en) | 2018-06-27 | 2020-01-02 | Arla Foods Amba | Acidic beta-lactoglobulin beverage preparation |
| EP3937648B1 (en) * | 2019-03-15 | 2023-12-13 | Arla Foods amba | Novel high protein, acidified, dairy product, method of producing it, protein powder and use thereof |
| US20230051969A1 (en) * | 2019-12-30 | 2023-02-16 | Arla Foods Amba | Method of producing dense whey protein nanogels, the resulting whey protein nanogels or nanogel compositions, and food products containing such whey protein nanogels or nanogel compositions |
| CN114836458B (zh) * | 2022-05-12 | 2024-04-02 | 天津大学 | 增强鲫希瓦氏菌核黄素合成促进mo降解和电能回收方法 |
| US12349701B2 (en) | 2023-01-13 | 2025-07-08 | Leprino Foods Company | Denatured milk proteins, methods of making, and protein fortified foods |
| WO2025057716A1 (ja) * | 2023-09-15 | 2025-03-20 | 森永乳業株式会社 | 殺菌乳飲料及びその製造方法 |
| CN117907169A (zh) * | 2023-11-15 | 2024-04-19 | 内蒙古蒙牛乳业(集团)股份有限公司 | 体积加权平均直径在后热处理酸奶颗粒感评估中的应用 |
| US20250160353A1 (en) * | 2023-11-22 | 2025-05-22 | Leprino Foods Company | Co-particulated milk proteins and methods of making them |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013187519A1 (ja) | 2012-06-15 | 2013-12-19 | 森永乳業株式会社 | 改質ホエイ組成物の製造方法、改質ホエイ組成物、カルシウム増強改質ホエイ組成物の製造方法 |
| JP2015171373A (ja) | 2009-04-15 | 2015-10-01 | フォンテラ コ−オペレイティブ グループ リミティド | 乳製品およびプロセス |
| JP2016533726A (ja) | 2013-10-23 | 2016-11-04 | アーラ フーズ エエムビエArla Foods amba | 高タンパクの変性ホエータンパク質組成物、関連製品、製造方法、およびその使用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096731A (en) * | 1989-06-16 | 1992-03-17 | John Labatt Limited/John Labatt Limitee | Reduced fat yogurt |
| NL9101127A (nl) | 1991-06-28 | 1993-01-18 | Friesland Frico Domo Coop | Werkwijze voor de bereiding van een op magere melk gelijkend produkt. |
| JP2683492B2 (ja) | 1993-09-07 | 1997-11-26 | 雪印乳業株式会社 | ミセル状ホエー蛋白質、その溶液、その粉末およびミセル状ホエー蛋白質の製造法 |
| DE19950240A1 (de) | 1999-10-19 | 2001-05-17 | Thomas Spiegel | Herstellung eines Molkenproteinkonzentrates mit erhöhtem Gehalt an alpha-Lactalbumin |
| US6605311B2 (en) | 2000-06-22 | 2003-08-12 | The Procter & Gamble Company | Insoluble protein particles |
| WO2006058538A1 (en) | 2004-11-30 | 2006-06-08 | Cp Kelco Aps | Method for producing a denatured protein material |
| WO2007108709A1 (en) | 2006-03-23 | 2007-09-27 | Fonterra Co-Operative Group Limited | Method for preparing a dried modified whey protein |
| ES2373400T3 (es) | 2006-03-27 | 2012-02-03 | Nestec S.A. | Micelas de proteína láctea. |
| SE530577C2 (sv) | 2006-11-22 | 2008-07-08 | Tetra Laval Holdings & Finance | Metod för att behandla ett vassleproteinkoncentrat genom mikropartikulering |
| US20090137554A1 (en) | 2007-10-22 | 2009-05-28 | Wyeth | 1,4,5,6-TETRAHYDRO -PYRROLO[2,3-d]AZEPINES AND -IMIDAZO[4,5-d]AZEPINES AS MODULATORS OF NUCLEAR RECEPTOR ACTIVITY |
| ES2439050T3 (es) * | 2009-07-10 | 2014-01-21 | Arla Foods Amba | Un producto lácteo acidificado bebible basado en suero ácido y un procedimiento para su elaboración |
| WO2011066880A2 (en) | 2009-09-17 | 2011-06-09 | Danone, S.A. | Pasteurised and fermented dairy product and procedure for preparing such product |
| WO2012081971A1 (en) | 2010-12-17 | 2012-06-21 | N.V. Nutricia | Whey protein composition with a reduced astringency |
| DE102012216990A1 (de) * | 2011-09-21 | 2013-03-21 | Hochschule Anhalt (Fh) | Verfahren zur Mikropartikulierung von Molkeneiweiß |
| PL2583566T3 (pl) | 2011-10-21 | 2016-01-29 | Nestec Sa | Micele serwatkowego białka do zwiększania masy mięśni i sprawności |
| EP2583563A1 (en) | 2011-10-21 | 2013-04-24 | Nestec S.A. | Whey protein micelles against muscle atrophy and sarcopenia |
| CN104202998B (zh) | 2011-11-02 | 2017-05-10 | 恒天然集团 | 乳制品和方法 |
| US10834935B2 (en) | 2012-02-01 | 2020-11-17 | Koninklijke Douwe Egberts B.V. | Dairy mineral-fortified liquid dairy products and methods of making |
| EA035744B1 (ru) * | 2013-10-23 | 2020-08-05 | Арла Фудс Амба | Содержащие cmp высокобелковые композиции денатурированного сывороточного белка, содержащие их продукты и их применения |
| ES2962884T3 (es) | 2013-10-23 | 2024-03-21 | Arla Foods Amba | Preparación de fruta y verdura, rica en proteína y métodos y productos alimentarios relacionados |
| FI127843B (en) | 2014-08-28 | 2019-04-15 | Valio Oy | Prepared acidified milk protein products and process for their preparation |
| AU2015344999C1 (en) | 2014-11-14 | 2023-02-16 | Arla Foods Amba | Whey protein-based, high protein, yoghurt-like product, ingredient suitable for its production, and method of production |
| US11324229B2 (en) | 2017-02-17 | 2022-05-10 | Arla Foods Amba | High-protein, acidified, liquid dairy product having a reduced viscosity, method of producing it, and related ingredients |
-
2018
- 2018-02-14 US US16/486,737 patent/US11324229B2/en active Active
- 2018-02-14 PT PT187042510T patent/PT3582622T/pt unknown
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- 2018-02-14 WO PCT/EP2018/053665 patent/WO2018149869A1/en not_active Ceased
- 2018-02-14 EP EP23203468.6A patent/EP4295694A3/en active Pending
- 2018-02-14 JP JP2019544074A patent/JP7212624B2/ja active Active
- 2018-02-14 FI FIEP18704251.0T patent/FI3582622T3/fi active
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-
2022
- 2022-04-05 US US17/713,806 patent/US12290079B2/en active Active
- 2022-10-21 JP JP2022169421A patent/JP2023017803A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015171373A (ja) | 2009-04-15 | 2015-10-01 | フォンテラ コ−オペレイティブ グループ リミティド | 乳製品およびプロセス |
| WO2013187519A1 (ja) | 2012-06-15 | 2013-12-19 | 森永乳業株式会社 | 改質ホエイ組成物の製造方法、改質ホエイ組成物、カルシウム増強改質ホエイ組成物の製造方法 |
| JP2016533726A (ja) | 2013-10-23 | 2016-11-04 | アーラ フーズ エエムビエArla Foods amba | 高タンパクの変性ホエータンパク質組成物、関連製品、製造方法、およびその使用 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023017803A (ja) * | 2017-02-17 | 2023-02-07 | アーラ フーズ エエムビエ | 低下した粘度を有する高タンパク酸性液体乳製品、それを製造する方法及び関連する成分 |
| US12290079B2 (en) | 2017-02-17 | 2025-05-06 | Arla Foods Amba | High-protein, acidified, liquid dairy product having a reduced viscosity, method of producing it, and related ingredients |
Also Published As
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| US20200008439A1 (en) | 2020-01-09 |
| US20220225629A1 (en) | 2022-07-21 |
| WO2018149869A1 (en) | 2018-08-23 |
| US11324229B2 (en) | 2022-05-10 |
| PT3582622T (pt) | 2024-01-04 |
| FI3582622T3 (fi) | 2024-01-10 |
| EP3582622B1 (en) | 2023-10-18 |
| EP4295694A2 (en) | 2023-12-27 |
| DK3582622T3 (da) | 2024-01-02 |
| CN110621164A (zh) | 2019-12-27 |
| JP2020507330A (ja) | 2020-03-12 |
| EP3582622A1 (en) | 2019-12-25 |
| JP2023017803A (ja) | 2023-02-07 |
| PL3582622T3 (pl) | 2024-03-25 |
| US12290079B2 (en) | 2025-05-06 |
| EP4295694A3 (en) | 2024-02-28 |
| HRP20231746T1 (hr) | 2024-04-26 |
| CN110621164B (zh) | 2023-04-04 |
| ES2967096T3 (es) | 2024-04-26 |
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