JP7188385B2 - Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法 - Google Patents

Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法 Download PDF

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Publication number
JP7188385B2
JP7188385B2 JP2019523137A JP2019523137A JP7188385B2 JP 7188385 B2 JP7188385 B2 JP 7188385B2 JP 2019523137 A JP2019523137 A JP 2019523137A JP 2019523137 A JP2019523137 A JP 2019523137A JP 7188385 B2 JP7188385 B2 JP 7188385B2
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gene
protein
target substance
activity
microorganism
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JP2019531758A (ja
JP2019531758A5 (enExample
Inventor
ミッツ，ベンジャミン
ロシュ，クリスティーン
ケリー，ピーター
さやか 朝里
未来 戸矢崎
啓太 福井
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Ajinomoto Co Inc
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Ajinomoto Co Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2019523137A 2016-10-26 2017-10-26 Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法 Active JP7188385B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662413044P 2016-10-26 2016-10-26
US62/413,044 2016-10-26
US201662417609P 2016-11-04 2016-11-04
US62/417,609 2016-11-04
PCT/JP2017/038798 WO2018079686A1 (en) 2016-10-26 2017-10-26 Method for producing l-methionine or metabolites requiring s-adenosylmethionine for synthesis

Publications (3)

Publication Number Publication Date
JP2019531758A JP2019531758A (ja) 2019-11-07
JP2019531758A5 JP2019531758A5 (enExample) 2020-12-03
JP7188385B2 true JP7188385B2 (ja) 2022-12-13

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JP2019523137A Active JP7188385B2 (ja) 2016-10-26 2017-10-26 Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法

Country Status (5)

Country Link
US (1) US20190241914A1 (enExample)
EP (1) EP3532631A1 (enExample)
JP (1) JP7188385B2 (enExample)
CN (1) CN109963947B (enExample)
WO (1) WO2018079686A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020203885A1 (ja) 2019-03-29 2020-10-08 味の素株式会社 アロラクトースの製造法
EP3967676A4 (en) 2019-05-08 2023-02-08 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF VANILLIN
WO2021177392A1 (ja) 2020-03-04 2021-09-10 味の素株式会社 変異型トランスグルタミナーゼ

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009501548A (ja) 2005-07-18 2009-01-22 ビーエーエスエフ ソシエタス・ヨーロピア 微生物におけるメチオニン生産のためのジメチルジスルフィドの使用
JP2009501512A (ja) 2005-06-17 2009-01-22 アイアンウッド ファーマシューティカルズ インコーポレイテッド 改良されたアミノ酸及び代謝産物生合成
JP2015519917A (ja) 2012-06-18 2015-07-16 メタボリック エクスプローラー メチオニンの発酵生産のための組換え微生物

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5089592A (enExample) 1973-12-13 1975-07-18
JPS57134500A (en) 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
JPS58192900A (ja) 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
JPH01191686A (ja) 1988-01-26 1989-08-01 Mitsubishi Petrochem Co Ltd 複合プラスミド
FR2627508B1 (fr) 1988-02-22 1990-10-05 Eurolysine Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede
JP2678995B2 (ja) 1988-09-08 1997-11-19 三菱化学株式会社 トリプトフアンシンターゼの製造法
US5185262A (en) 1988-07-27 1993-02-09 Mitsubishi Petrochemical Co., Ltd. DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism
JPH02207791A (ja) 1989-02-07 1990-08-17 Ajinomoto Co Inc 微生物の形質転換法
JP2973446B2 (ja) 1990-01-11 1999-11-08 三菱化学株式会社 新規プラスミドベクター
JPH07108228B2 (ja) 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
JPH05244941A (ja) 1992-03-03 1993-09-24 Toyo Ink Mfg Co Ltd Ｎａｄｈ依存性パラヒドロキシ安息香酸ヒドロキシラーゼ及びその製造方法
US5272073A (en) 1992-06-30 1993-12-21 Purdue Research Foundation Biocatalytic synthesis of catechol from glucose
JPH0775589A (ja) 1993-09-08 1995-03-20 Kawasaki Steel Corp プロトカテキュ酸の製造方法
AU4431196A (en) 1995-01-23 1996-08-14 Novo Nordisk A/S Dna integration by transposition
JPH0970291A (ja) 1995-06-30 1997-03-18 Ajinomoto Co Inc 人工トランスポゾンを用いた遺伝子増幅方法
JP4168463B2 (ja) 1996-12-05 2008-10-22 味の素株式会社 Ｌ−リジンの製造法
AU756507B2 (en) 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU6043399A (en) 1998-09-18 2000-04-10 Board Of Trustees Of Michigan State University Synthesis of vanillin from a carbon source
JP2000262288A (ja) 1999-03-16 2000-09-26 Ajinomoto Co Inc コリネ型細菌の温度感受性プラスミド
US7846697B2 (en) 2003-06-19 2010-12-07 BLMaps Method of producing a low molecular weight organic compound in a cell
WO2005010794A2 (en) 2003-07-29 2005-02-03 Ajinomoto Co., Inc. Method for determining metabolic flux affecting substance production
JP4882063B2 (ja) 2005-10-12 2012-02-22 国立大学法人東京農工大学 テレフタル酸の代謝に関与する新規遺伝子
BRPI0617491B1 (pt) 2005-10-18 2021-04-27 Ajinomoto Co., Inc Processo para produção de ácido succínico
RU2418069C2 (ru) 2006-09-29 2011-05-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Способ конструирования рекомбинантных бактерий, принадлежащих к роду pantoea, и способ продукции l-аминокислот с использованием бактерий, принадлежащих к роду pantoea
JP2010207094A (ja) 2009-03-06 2010-09-24 Genaris Inc プロトカテク酸の製造法
MX392155B (es) 2011-08-08 2025-03-21 Int Flavors & Fragrances Inc Composiciones y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina.
PE20141569A1 (es) 2011-11-11 2014-11-08 Ajinomoto Kk Metodo para producir una sustancia diana mediante fermentacion
EP2914733A1 (en) 2012-11-05 2015-09-09 Evolva SA Vanillin synthase

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009501512A (ja) 2005-06-17 2009-01-22 アイアンウッド ファーマシューティカルズ インコーポレイテッド 改良されたアミノ酸及び代謝産物生合成
JP2009501548A (ja) 2005-07-18 2009-01-22 ビーエーエスエフ ソシエタス・ヨーロピア 微生物におけるメチオニン生産のためのジメチルジスルフィドの使用
JP2015519917A (ja) 2012-06-18 2015-07-16 メタボリック エクスプローラー メチオニンの発酵生産のための組換え微生物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Q8NNQ9; Methionine synthase II (Cobalamin-independent) ，2016年03月16日，2021年11月12日検索、インターネット<https://www.uniprot.org/uniprot/Q8NNQ9.txt?version=68>

Also Published As

Publication number Publication date
JP2019531758A (ja) 2019-11-07
CN109963947B (zh) 2023-07-04
WO2018079686A1 (en) 2018-05-03
EP3532631A1 (en) 2019-09-04
US20190241914A1 (en) 2019-08-08
CN109963947A (zh) 2019-07-02

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