JP7181880B2 - 免疫療法のためのコア／シェル構造プラットホーム - Google Patents

免疫療法のためのコア／シェル構造プラットホーム Download PDF

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JP7181880B2
JP7181880B2 JP2019540384A JP2019540384A JP7181880B2 JP 7181880 B2 JP7181880 B2 JP 7181880B2 JP 2019540384 A JP2019540384 A JP 2019540384A JP 2019540384 A JP2019540384 A JP 2019540384A JP 7181880 B2 JP7181880 B2 JP 7181880B2
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ハイファ シェン，
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ザ・メソジスト・ホスピタル
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    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2019540384A 2017-01-27 2018-01-26 免疫療法のためのコア／シェル構造プラットホーム Active JP7181880B2 (ja)

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JP2022184788A JP7509504B2 (ja) 2017-01-27 2022-11-18 免疫療法のためのコア／シェル構造プラットホーム

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US201762451575P 2017-01-27 2017-01-27
US62/451,575 2017-01-27
PCT/US2018/015601 WO2018140826A1 (en) 2017-01-27 2018-01-26 Core/shell structure platform for immunotherapy

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JP2020505403A JP2020505403A (ja) 2020-02-20
JP2020505403A5 JP2020505403A5 (enExample) 2021-03-11
JP7181880B2 true JP7181880B2 (ja) 2022-12-01

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US (2) US11382964B2 (enExample)
EP (3) EP4008344B1 (enExample)
JP (2) JP7181880B2 (enExample)
KR (2) KR102627347B1 (enExample)
CN (2) CN115845040A (enExample)
AU (1) AU2018212887B2 (enExample)
CA (1) CA3051136A1 (enExample)
DK (2) DK3573656T3 (enExample)
ES (2) ES2905591T3 (enExample)
SG (1) SG11201906744VA (enExample)
WO (1) WO2018140826A1 (enExample)

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EP3624810A4 (en) * 2017-05-18 2021-02-17 The Regents of The University of California NANO-ACTIVATED IMMUNOTHERAPY FOR CANCER DISEASES
US11433143B2 (en) 2017-05-18 2022-09-06 The Regents Of The University Of California Nano-enabled immunotherapy in cancer
EP3836964A1 (en) * 2018-08-15 2021-06-23 University of Florida Research Foundation, Inc. Methods of sensitizing tumors to treatment with immune checkpoint inhibitors
JP2022506839A (ja) * 2018-11-07 2022-01-17 モデルナティエックス インコーポレイテッド Ｒｎａがんワクチン
CN109260157A (zh) * 2018-11-19 2019-01-25 上海交通大学 一种正电荷多肽脂质体纳米制剂及其制备方法与应用
US20220088221A1 (en) * 2019-01-12 2022-03-24 The Methodist Hospital Self-assembled peptide nanoparticle and use thereof
WO2020183238A1 (en) * 2019-03-14 2020-09-17 Engene, Inc. Reversible coating of chitosan-nucleic acid nanoparticles and methods of their use
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US20220307024A1 (en) * 2019-06-17 2022-09-29 Alnylam Pharmaceuticals, Inc. Delivery of oligonucleotides to the striatum
EP4013880A1 (en) * 2019-08-14 2022-06-22 CureVac AG Rna combinations and compositions with decreased immunostimulatory properties
DE102019122014A1 (de) * 2019-08-15 2021-02-18 Technische Universität Darmstadt Reduktion der Knochenresorption, insbesondere bei chronischen Gelenkerkrankungen
US20220370488A1 (en) * 2019-10-22 2022-11-24 The Johns Hopkins University Mucus penetrating particle compositions and methods of use thereof enhancing immune response
KR102579284B1 (ko) * 2020-09-22 2023-09-18 비피진 주식회사 신규의 cd47 바인더와 폴리뉴클레오티드를 포함하는 암 치료를 위한 리포좀 복합체
CN112245575B (zh) * 2020-10-26 2024-07-26 上海杏禾医疗科技有限公司 含支化聚合物和mRNA的核壳结构的抗肿瘤疫苗及其用途
WO2023034957A1 (en) * 2021-09-03 2023-03-09 University Of Connecticut Stabilization of antigens for long term administration in transdermal microneedle patches
CN114699420A (zh) * 2022-03-08 2022-07-05 南方科技大学 一种用于治疗前列腺癌组合物及其制备方法与应用
CN114699538A (zh) * 2022-04-02 2022-07-05 中国药科大学 一种核-壳式高效基因药物递送系统及其制备方法
BE1031669B1 (fr) * 2023-06-02 2025-01-14 Inhatarget Therapeutics Composition pharmaceutique pour inhalation
BE1031668B1 (fr) * 2023-06-02 2025-01-16 Inhatarget Therapeutics Composition pharmaceutique pour inhalation
CN117045809B (zh) * 2023-09-27 2025-08-29 国家纳米科学中心 异种哺乳动物细胞来源的囊泡在制备疫苗载体中的应用
KR20250063352A (ko) * 2023-11-01 2025-05-08 가톨릭대학교 산학협력단 mRNA가 봉입된 이중 나노입자, 이의 제조방법 및 이의 약학적 용도
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