JP7100634B2 - Ｃｎｓ疾患及び疼痛の治療におけるムスカリンｍ１及び／又はｍ４受容体の調節因子として活性を有する複素環式化合物。 - Google Patents

Ｃｎｓ疾患及び疼痛の治療におけるムスカリンｍ１及び／又はｍ４受容体の調節因子として活性を有する複素環式化合物。 Download PDF

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JP7100634B2
JP7100634B2 JP2019520420A JP2019520420A JP7100634B2 JP 7100634 B2 JP7100634 B2 JP 7100634B2 JP 2019520420 A JP2019520420 A JP 2019520420A JP 2019520420 A JP2019520420 A JP 2019520420A JP 7100634 B2 JP7100634 B2 JP 7100634B2
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ethyl
carboxylate
cyclohexane
diazepan
cyano
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JP2019530725A5 (enExample
JP2019530725A (ja
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ブラウン，ジャイルズ・アルバート
コングリーヴ，マイルズ・スチュアート
ピックワース，マーク
テハン，ベンジャミン・ジェラルド
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Nxera Pharma UK Ltd
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Heptares Therapeutics Ltd
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JP2019520420A 2016-10-14 2017-10-16 Ｃｎｓ疾患及び疼痛の治療におけるムスカリンｍ１及び／又はｍ４受容体の調節因子として活性を有する複素環式化合物。 Active JP7100634B2 (ja)

Applications Claiming Priority (5)

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US201662408468P 2016-10-14 2016-10-14
GB1617454.2 2016-10-14
GBGB1617454.2A GB201617454D0 (en) 2016-10-14 2016-10-14 Pharmaceutical compounds
US62/408,468 2016-10-14
PCT/GB2017/053115 WO2018069732A1 (en) 2016-10-14 2017-10-16 Heterocyclic compounds having activity as modulators of muscarinic m1 and/or m4 receptors in the treatment of cns diseases and pains.

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JP2019530725A JP2019530725A (ja) 2019-10-24
JP2019530725A5 JP2019530725A5 (enExample) 2020-11-26
JP7100634B2 true JP7100634B2 (ja) 2022-07-13

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US (1) US11834407B2 (enExample)
EP (1) EP3526207B1 (enExample)
JP (1) JP7100634B2 (enExample)
CN (1) CN109996792B (enExample)
DK (1) DK3526207T3 (enExample)
ES (1) ES2898206T3 (enExample)
GB (1) GB201617454D0 (enExample)
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GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201810245D0 (en) * 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819961D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) * 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds
PH12022550860A1 (en) 2019-10-09 2023-06-14 Novartis Ag 5-oxa-2-azaspiro[3.4]octane derivatives as m4 agonists
UY38906A (es) 2019-10-09 2021-05-31 Novartis Ag Compuestos 2- derivados de azaspiro[3,4]octano como agonistas de m4 y composiciones de los mismos
CN114728964A (zh) * 2019-11-22 2022-07-08 豪夫迈·罗氏有限公司 吡咯烷衍生物
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