JP7098600B2 - ３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体を有機金属亜鉛－アミン塩基と反応させることによる２－（３，６－ジハロピリジン－２－イル）－３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体及び関連化合物の製造方法 - Google Patents

３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体を有機金属亜鉛－アミン塩基と反応させることによる２－（３，６－ジハロピリジン－２－イル）－３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体及び関連化合物の製造方法 Download PDF

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JP7098600B2
JP7098600B2 JP2019508264A JP2019508264A JP7098600B2 JP 7098600 B2 JP7098600 B2 JP 7098600B2 JP 2019508264 A JP2019508264 A JP 2019508264A JP 2019508264 A JP2019508264 A JP 2019508264A JP 7098600 B2 JP7098600 B2 JP 7098600B2
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alkyl
cycloalkyl
formula
haloalkyl
alkoxy
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JP2019524828A (ja
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モスリン，マルク
フィッシャー，リュディガー
ヘイガー，ドミニク
ホフマイスター，ラウラ
カウシュ－ビジーズ，ニーナ
ヴィルケ，デイビッド
ウィロット，マシュー
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Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/824—Palladium

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2019508264A 2016-08-16 2017-08-09 ３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体を有機金属亜鉛－アミン塩基と反応させることによる２－（３，６－ジハロピリジン－２－イル）－３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体及び関連化合物の製造方法 Active JP7098600B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16184368.5 2016-08-16
EP16184368 2016-08-16
PCT/EP2017/070184 WO2018033448A1 (de) 2016-08-16 2017-08-09 Verfahren zur herstellung von 2-(3,6-dihalopyridin-2-yl)-3h-imidazol[4,5-c]pyridinderivaten und verwandten verbindungen durch umsetzung des 3h-imidazol[4,5-c]pyridinderivats mit einer metallorganischen zink-amin base

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JP2019524828A JP2019524828A (ja) 2019-09-05
JP7098600B2 true JP7098600B2 (ja) 2022-07-11

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JP2019508264A Active JP7098600B2 (ja) 2016-08-16 2017-08-09 ３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体を有機金属亜鉛－アミン塩基と反応させることによる２－（３，６－ジハロピリジン－２－イル）－３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体及び関連化合物の製造方法

Country Status (12)

Country Link
US (1) US10875858B2 (zh)
EP (1) EP3500568B1 (zh)
JP (1) JP7098600B2 (zh)
KR (1) KR102420235B1 (zh)
CN (1) CN109819653A (zh)
BR (1) BR112019003174B1 (zh)
DK (1) DK3500568T3 (zh)
ES (1) ES2833251T3 (zh)
IL (1) IL264780B (zh)
MX (1) MX2019001917A (zh)
TW (1) TWI743165B (zh)
WO (1) WO2018033448A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3636645A1 (de) * 2018-10-11 2020-04-15 Bayer Aktiengesellschaft Verfahren zur herstellung schwefel-substituierter pyridinderivate
TWI820231B (zh) 2018-10-11 2023-11-01 德商拜耳廠股份有限公司 用於製備經取代咪唑衍生物之方法
WO2020074558A1 (de) 2018-10-11 2020-04-16 Bayer Aktiengesellschaft Verfahren zur herstellung von imidazolderivaten

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JP2013503846A (ja) 2009-09-01 2013-02-04 ファイザー・インク ベンズイミダゾール誘導体
WO2015002211A1 (ja) 2013-07-01 2015-01-08 住友化学株式会社 縮合複素環化合物及びその有害生物防除用途
JP2016102104A (ja) 2015-09-08 2016-06-02 住友化学株式会社 有害生物防除組成物およびその用途
WO2018202501A1 (de) 2017-05-02 2018-11-08 Bayer Aktiengesellschaft 2-(het)aryl-substituierte kondensierte heterocyclen-derivate als schädlingsbekämpfungsmittel
JP2019529405A (ja) 2016-09-14 2019-10-17 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ハロゲン化二環式化合物の製造方法
JP6738341B2 (ja) 2015-02-05 2020-08-12 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 有害生物防除剤としての２−（ヘト）アリール置換された縮合二環式複素環誘導体

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CA2004911A1 (en) * 1988-12-22 1990-06-22 Mitsuaki Ohta 4,5,6,7-tetrahydrobenzimidazole derivatives
EP0844998B1 (de) * 1995-08-10 2003-04-23 Bayer CropScience AG Halogenbenzimidazole und ihre verwendung als mikrobizide
PA8535601A1 (es) 2000-12-21 2002-11-28 Pfizer Derivados benzimidazol y piridilimidazol como ligandos para gabaa
BRPI0514675A (pt) * 2004-09-10 2008-06-17 Pfizer Prod Inc ligantes de éter difenìlico terapêuticos
US7767687B2 (en) 2004-12-13 2010-08-03 Biogen Idec Ma Inc. Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors
MX2008008277A (es) * 2005-12-21 2009-03-04 Janssen Pharmaceutica Nv Triazolopiridazinas como moduladores de tirosina cinasa.
US8754114B2 (en) * 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
CN103261170B (zh) 2010-12-24 2016-08-24 住友化学株式会社 稠杂环化合物及其用于害虫防治的用途
CN104902751A (zh) * 2012-11-09 2015-09-09 住友化学株式会社 促进植物生长的方法
CA2895504A1 (en) 2012-12-20 2014-06-26 Merck Sharp & Dohme Corp. Substituted imidazopyridines as hdm2 inhibitors
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AR099677A1 (es) * 2014-03-07 2016-08-10 Sumitomo Chemical Co Compuesto heterocíclico fusionado y su uso para el control de plagas
WO2015171951A1 (en) * 2014-05-07 2015-11-12 The Regents Of The University Of Colorado, A Body Corporate 2-(4-aryl-1h-imidazol-1-yl)aniline compounds
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JP2013503846A (ja) 2009-09-01 2013-02-04 ファイザー・インク ベンズイミダゾール誘導体
WO2015002211A1 (ja) 2013-07-01 2015-01-08 住友化学株式会社 縮合複素環化合物及びその有害生物防除用途
JP6738341B2 (ja) 2015-02-05 2020-08-12 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 有害生物防除剤としての２−（ヘト）アリール置換された縮合二環式複素環誘導体
JP2016102104A (ja) 2015-09-08 2016-06-02 住友化学株式会社 有害生物防除組成物およびその用途
JP2019529405A (ja) 2016-09-14 2019-10-17 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ハロゲン化二環式化合物の製造方法
WO2018202501A1 (de) 2017-05-02 2018-11-08 Bayer Aktiengesellschaft 2-(het)aryl-substituierte kondensierte heterocyclen-derivate als schädlingsbekämpfungsmittel

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Publication number Publication date
BR112019003174B1 (pt) 2022-10-25
KR20190038890A (ko) 2019-04-09
TWI743165B (zh) 2021-10-21
US20190202829A1 (en) 2019-07-04
KR102420235B1 (ko) 2022-07-12
BR112019003174A2 (pt) 2019-06-18
EP3500568B1 (de) 2020-09-23
US10875858B2 (en) 2020-12-29
WO2018033448A1 (de) 2018-02-22
CN109819653A (zh) 2019-05-28
JP2019524828A (ja) 2019-09-05
IL264780B (en) 2021-09-30
EP3500568A1 (de) 2019-06-26
MX2019001917A (es) 2019-07-15
TW201819375A (zh) 2018-06-01
DK3500568T3 (da) 2020-12-14
ES2833251T3 (es) 2021-06-14

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