JP7089299B2 - 磁性モジュール及びカバーモジュールを用いた核酸抽出方法、磁性モジュール、カバーモジュール、部品、並びに自動化システム - Google Patents
磁性モジュール及びカバーモジュールを用いた核酸抽出方法、磁性モジュール、カバーモジュール、部品、並びに自動化システム Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/284—Magnetic plugs and dipsticks with associated cleaning means, e.g. retractable non-magnetic sleeve
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/286—Magnetic plugs and dipsticks disposed at the inner circumference of a recipient, e.g. magnetic drain bolt
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/06—Tubular
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
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- B03C2201/28—Parts being easily removable for cleaning purposes
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- G01—MEASURING; TESTING
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00564—Handling or washing solid phase elements, e.g. beads
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1053—General features of the devices using the transfer device for another function for separating part of the liquid, e.g. filters, extraction phase
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Sustainable Development (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20170092982 | 2017-07-21 | ||
KR10-2017-0092982 | 2017-07-21 | ||
US201862633627P | 2018-02-22 | 2018-02-22 | |
US62/633,627 | 2018-02-22 | ||
PCT/KR2018/008219 WO2019017726A2 (fr) | 2017-07-21 | 2018-07-20 | Modules de transfert de billes magnétiques, système automatisé les comprenant et procédé d'extraction d'acides nucléiques l'utilisant |
Publications (2)
Publication Number | Publication Date |
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JP2020534792A JP2020534792A (ja) | 2020-12-03 |
JP7089299B2 true JP7089299B2 (ja) | 2022-06-22 |
Family
ID=69284237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020501391A Active JP7089299B2 (ja) | 2017-07-21 | 2018-07-20 | 磁性モジュール及びカバーモジュールを用いた核酸抽出方法、磁性モジュール、カバーモジュール、部品、並びに自動化システム |
Country Status (8)
Country | Link |
---|---|
US (2) | US11674971B2 (fr) |
EP (1) | EP3655783A4 (fr) |
JP (1) | JP7089299B2 (fr) |
KR (1) | KR102378429B1 (fr) |
CN (1) | CN110945363B (fr) |
AU (3) | AU2018303111B2 (fr) |
BR (1) | BR112020001252B1 (fr) |
WO (1) | WO2019017726A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102526182B1 (ko) * | 2021-03-31 | 2023-04-27 | 주식회사 제놀루션 | 핵산 또는 생물학적 물질의 추출장치 및 추출방법 |
CN113621503A (zh) * | 2021-08-11 | 2021-11-09 | 马晟利 | 一种用于核酸检测的便携快捷式核酸提取装置 |
TWI807759B (zh) * | 2022-04-06 | 2023-07-01 | 關鍵禾芯科技股份有限公司 | 核酸篩檢方法及其篩檢套組 |
Citations (4)
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JP2004229657A (ja) | 2003-01-29 | 2004-08-19 | Bionex Inc | 核酸又は様々な生物学的物質を分離及び精製するためのキットと、このキットを用いて生物学的物質の分離又は精製操作を自動化するためのシステム |
JP2013544097A (ja) | 2010-11-18 | 2013-12-12 | バイオニア コーポレーション | エアロゾル防止のための自動精製装備及び自動精製方法 |
CN204958942U (zh) | 2015-09-02 | 2016-01-13 | 苏州东胜兴业科学仪器有限公司 | 磁棒管套、多联组件及核酸提取仪 |
CN103992940B (zh) | 2014-05-27 | 2016-03-16 | 广州冠科生物科技有限公司 | 一种提取生物活性物质的仪器 |
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GB8808583D0 (en) | 1988-04-12 | 1988-05-11 | Flow Lab | Pipette tip pickup apparatus |
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JP3794734B2 (ja) | 1995-08-07 | 2006-07-12 | オリンパス株式会社 | 液体試料の分析検査方法 |
DE19917375C2 (de) | 1999-04-16 | 2001-09-27 | Hamilton Bonaduz Ag Bonaduz | Pipettiereinheit |
US6645431B2 (en) * | 2001-01-22 | 2003-11-11 | Thomas W. Astle | Apparatus for automated magnetic separation of materials in laboratory trays |
JP2005523692A (ja) * | 2002-04-26 | 2005-08-11 | アボット・ラボラトリーズ | 生物学的検定において磁性粒子を処理するための構造体および方法 |
US7105129B2 (en) | 2002-05-15 | 2006-09-12 | Genetix Limited | Liquid handling robot for well plates |
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KR100720044B1 (ko) | 2006-04-27 | 2007-05-18 | 코아바이오시스템 주식회사 | 생물학적 물질 또는 핵산 추출 자동화 장치 |
JP2011516075A (ja) * | 2008-04-09 | 2011-05-26 | バイオニア コーポレーション | 自動精製装置、マルチウェルプレートキット及び生物学的試料からヘキサンを抽出する方法 |
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JP5292267B2 (ja) * | 2009-12-16 | 2013-09-18 | 株式会社日立ハイテクノロジーズ | 試料処理装置、試料処理方法及びこれらに使用する反応容器 |
EP2410342B1 (fr) | 2010-06-29 | 2020-02-19 | F.Hoffmann-La Roche Ag | Dispositif de pipetage avec pointes de pipette mobiles indépendamment |
JP5650056B2 (ja) * | 2011-05-30 | 2015-01-07 | 株式会社日立ハイテクノロジーズ | 試料処理装置、および試料処理方法 |
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EP2618157A1 (fr) * | 2012-01-17 | 2013-07-24 | Eppendorf Ag | Appareil de laboratoire pour traiter une section de réception d'échantillons avec un dispositif d'outil magnétique, dispositif d'outil magnétique, dispositif de réception d'échantillons pour une utilisation avec le dispositif d'outil magnétique et procédé pour la réalisation d'une étape de travail avec au moins un échantillon de fluide utilisant un champ magnétique |
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2018
- 2018-07-20 AU AU2018303111A patent/AU2018303111B2/en active Active
- 2018-07-20 KR KR1020207002308A patent/KR102378429B1/ko active IP Right Grant
- 2018-07-20 JP JP2020501391A patent/JP7089299B2/ja active Active
- 2018-07-20 WO PCT/KR2018/008219 patent/WO2019017726A2/fr unknown
- 2018-07-20 US US16/632,406 patent/US11674971B2/en active Active
- 2018-07-20 EP EP18834492.3A patent/EP3655783A4/fr active Pending
- 2018-07-20 CN CN201880049116.0A patent/CN110945363B/zh active Active
- 2018-07-20 BR BR112020001252-1A patent/BR112020001252B1/pt active IP Right Grant
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2021
- 2021-06-25 AU AU2021204362A patent/AU2021204362A1/en not_active Abandoned
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2023
- 2023-04-28 US US18/308,868 patent/US20230258677A1/en active Pending
- 2023-08-25 AU AU2023219975A patent/AU2023219975A1/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2004229657A (ja) | 2003-01-29 | 2004-08-19 | Bionex Inc | 核酸又は様々な生物学的物質を分離及び精製するためのキットと、このキットを用いて生物学的物質の分離又は精製操作を自動化するためのシステム |
JP2013544097A (ja) | 2010-11-18 | 2013-12-12 | バイオニア コーポレーション | エアロゾル防止のための自動精製装備及び自動精製方法 |
CN103992940B (zh) | 2014-05-27 | 2016-03-16 | 广州冠科生物科技有限公司 | 一种提取生物活性物质的仪器 |
CN204958942U (zh) | 2015-09-02 | 2016-01-13 | 苏州东胜兴业科学仪器有限公司 | 磁棒管套、多联组件及核酸提取仪 |
Also Published As
Publication number | Publication date |
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WO2019017726A3 (fr) | 2019-03-28 |
BR112020001252A2 (pt) | 2020-07-21 |
KR102378429B1 (ko) | 2022-03-25 |
BR112020001252B1 (pt) | 2023-03-21 |
EP3655783A4 (fr) | 2021-03-31 |
CN110945363A (zh) | 2020-03-31 |
AU2018303111A1 (en) | 2020-02-06 |
US20230258677A1 (en) | 2023-08-17 |
CN110945363B (zh) | 2024-04-16 |
US11674971B2 (en) | 2023-06-13 |
WO2019017726A2 (fr) | 2019-01-24 |
JP2020534792A (ja) | 2020-12-03 |
AU2018303111B2 (en) | 2021-07-15 |
AU2023219975A1 (en) | 2023-09-14 |
KR20200012027A (ko) | 2020-02-04 |
US20200209271A1 (en) | 2020-07-02 |
EP3655783A2 (fr) | 2020-05-27 |
AU2021204362A1 (en) | 2021-07-22 |
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