JP7071748B2 - 胃内滞留システム - Google Patents
胃内滞留システム Download PDFInfo
- Publication number
- JP7071748B2 JP7071748B2 JP2019529639A JP2019529639A JP7071748B2 JP 7071748 B2 JP7071748 B2 JP 7071748B2 JP 2019529639 A JP2019529639 A JP 2019529639A JP 2019529639 A JP2019529639 A JP 2019529639A JP 7071748 B2 JP7071748 B2 JP 7071748B2
- Authority
- JP
- Japan
- Prior art keywords
- arm
- gastric
- arms
- grdf
- stomach
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
- A61F5/41—Devices for promoting penis erection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6871—Stomach
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/50—Prostheses not implantable in the body
- A61F2002/5016—Prostheses not implantable in the body adjustable
- A61F2002/5036—Prostheses not implantable in the body adjustable self-adjustable, e.g. self-learning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
- A61F5/41—Devices for promoting penis erection
- A61F2005/412—Devices for promoting penis erection by vacuum means
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Reproductive Health (AREA)
- Nursing (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Soil Working Implements (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662429095P | 2016-12-02 | 2016-12-02 | |
| US62/429,095 | 2016-12-02 | ||
| US201662430166P | 2016-12-05 | 2016-12-05 | |
| US62/430,166 | 2016-12-05 | ||
| PCT/US2017/064417 WO2018102799A1 (en) | 2016-12-02 | 2017-12-04 | Gastric residence system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019536800A JP2019536800A (ja) | 2019-12-19 |
| JP2019536800A5 JP2019536800A5 (https=) | 2020-10-22 |
| JP7071748B2 true JP7071748B2 (ja) | 2022-05-19 |
Family
ID=61025040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529639A Expired - Fee Related JP7071748B2 (ja) | 2016-12-02 | 2017-12-04 | 胃内滞留システム |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10737079B2 (https=) |
| EP (1) | EP3547974B1 (https=) |
| JP (1) | JP7071748B2 (https=) |
| CN (1) | CN110035718B (https=) |
| ES (1) | ES2966736T3 (https=) |
| IL (1) | IL266377B2 (https=) |
| WO (1) | WO2018102799A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11576859B2 (en) | 2015-10-23 | 2023-02-14 | Lyndra Therapeutics, Inc. | Gastric residence systems for sustained release of therapeutic agents and methods of use thereof |
| CA3006999A1 (en) * | 2015-12-01 | 2017-06-08 | Clexio Biosciences Ltd. | Gastric retentive devices |
| WO2017100367A1 (en) | 2015-12-08 | 2017-06-15 | Lyndra, Inc. | Geometric configurations for gastric residence systems |
| CN109310639A (zh) | 2016-05-27 | 2019-02-05 | 林德拉有限公司 | 用于胃驻留系统的材料结构 |
| JP2019532947A (ja) | 2016-09-30 | 2019-11-14 | リンドラ,インコーポレイティド | アダマンタン系薬物の持続的送達のための胃内滞留システム |
| CN110035718B (zh) | 2016-12-02 | 2021-04-06 | 克雷西奥生物科技有限公司 | 胃内滞留系统 |
| CA3066658A1 (en) | 2017-06-09 | 2018-12-13 | Lyndra, Inc. | Gastric residence systems with release rate-modulating films |
| CN111587088A (zh) * | 2017-11-28 | 2020-08-25 | 麻省理工学院 | 胃驻留电子装置 |
| WO2019111132A1 (en) | 2017-12-04 | 2019-06-13 | Clexio Biosciences Ltd. | Long acting gastric residence system |
| US12303659B2 (en) * | 2018-11-15 | 2025-05-20 | Massachusetts Institute Of Technology | Thermally controlled reconfigurable medical devices |
| BR112021018496A2 (pt) * | 2019-03-20 | 2021-11-30 | Lyndra Therapeutics Inc | Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica |
| AU2020242062B2 (en) * | 2019-03-20 | 2025-12-11 | Nortiva Bio, Inc. | Coatings for gastric residence dosage forms |
| US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
| MX2022003803A (es) * | 2019-10-01 | 2022-06-29 | Rani Therapeutics Llc | Dispositivo autodimensionable para suministrar una formulación a una pared de lumen. |
| US20220387312A1 (en) * | 2019-11-08 | 2022-12-08 | Lyndra Therapeutics, Inc. | Gastric residence systems having arms with controlled stiffness for improved gastric residence |
| WO2021092486A1 (en) * | 2019-11-08 | 2021-05-14 | Lyndra, Inc. | Formulations for release-rate modulating films for gastric residence systems |
| KR102391865B1 (ko) * | 2020-04-03 | 2022-04-27 | 재단법인대구경북과학기술원 | 약물 전달 디바이스 |
| IL300939A (en) * | 2020-08-30 | 2023-04-01 | Teva Pharma | Devices and methods for administering a drug with retention in the stomach |
| IL305602A (en) * | 2021-03-02 | 2023-11-01 | Teva Pharma | Retentive devices for gastrointestinal tract |
| WO2022195476A1 (en) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Gastroretentive devices for assessment of intragastric conditions |
| CA3229117A1 (en) | 2021-08-19 | 2023-02-23 | Dorit MIMROD | Method of treating parkinson's disease |
| CN115518052B (zh) * | 2022-09-22 | 2024-01-02 | 江苏集萃新型药物制剂技术研究所有限公司 | 胃滞留制剂及其制备方法 |
| WO2024134599A1 (en) * | 2022-12-21 | 2024-06-27 | Teva Pharmaceutical Industries Ltd. | Emptying monitoring system for gastrointestinal tract devices |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130072869A1 (en) | 2011-09-15 | 2013-03-21 | The Johns Hopkins University | Intra-Gastric Timed-Release Drug Delivery System |
| WO2015083171A1 (en) | 2013-12-05 | 2015-06-11 | Tulip Medical Ltd. | Retentive devices and systems for in-situ release of pharmaceutical active agents |
| WO2015187746A1 (en) | 2014-06-02 | 2015-12-10 | Teva Pharmaceutical Industries Ltd. | Expandable gastroretentive dosage form |
| WO2015191920A1 (en) | 2014-06-11 | 2015-12-17 | Massachusetts Institute Of Technology | Residence structures and related methods |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US1318259A (en) | 1919-10-07 | Resilient wheel | ||
| AU449029B2 (en) | 1969-08-28 | 1974-04-17 | Commonwealth Scientific And Industrial Research Organisation | Device for administration to ruminants |
| US4220153A (en) | 1978-05-08 | 1980-09-02 | Pfizer Inc. | Controlled release delivery system |
| US4735804A (en) | 1985-05-10 | 1988-04-05 | Merck & Co., Inc. | Drug delivery device which can be retained in the stomach for a controlled period of time |
| JPS6226215A (ja) * | 1985-05-10 | 1987-02-04 | メルク エンド カムパニ− インコ−ポレ−テツド | 一定に制御した時間内胃中に保持できる薬剤移送装置 |
| CA1273872A (en) | 1985-05-10 | 1990-09-11 | Larry J. Caldwell | Drug delivery device which can be retained in the stomach for a controlled period of time |
| US4767627A (en) | 1985-05-29 | 1988-08-30 | Merck & Co., Inc. | Drug delivery device which can be retained in the stomach for a controlled period of time |
| US5002772A (en) * | 1988-05-31 | 1991-03-26 | Pfizer Inc. | Gastric retention system for controlled drug release |
| JPH03163011A (ja) * | 1989-08-31 | 1991-07-15 | Yamanouchi Pharmaceut Co Ltd | 胃内滞留デバイス |
| IT1282650B1 (it) | 1996-02-19 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici |
| DE19850309A1 (de) * | 1998-10-30 | 2000-05-04 | Lohmann Therapie Syst Lts | Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer |
| IL133196A0 (en) | 1999-11-29 | 2001-03-19 | Yissum Res Dev Co | Gastroretentive controlled release pharmaceutical dosage forms |
| US6753011B2 (en) | 2000-01-14 | 2004-06-22 | Osmotica Corp | Combined diffusion/osmotic pumping drug delivery system |
| DE60123384T2 (de) | 2000-02-04 | 2007-08-02 | DepoMed, Inc., Menlo Park | Dosierungsform des typs "hülle und kern" mit einer wirkstofffreisetzung, die sich der nullten ordnung annähert |
| AR030557A1 (es) | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| US6488962B1 (en) | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
| AUPR839001A0 (en) * | 2001-10-19 | 2001-11-15 | Eli Lilly And Company | Dosage form, device and methods of treatment |
| CA2409552A1 (en) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
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| CN1750813A (zh) * | 2003-02-19 | 2006-03-22 | 尼莫科学有限公司 | 用于胃肠道和泌尿生殖道的自展装置 |
| US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
| TW200533391A (en) * | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
| IL166183A0 (en) | 2005-01-06 | 2006-01-15 | Yissum Res Dev Co | Novel diagnostic and imaging techniques of the gi tract |
| CA2613178A1 (en) | 2005-07-15 | 2007-01-25 | Kissei Pharmaceutical Co., Ltd. | Sustained release preparation |
| US8187633B2 (en) | 2005-11-03 | 2012-05-29 | Sun Pharma Advanced Research Company Limited | Controlled release coated tablets having prolonged gastric retention |
| CA2635313C (en) | 2005-12-29 | 2013-12-31 | Osmotica Corp. | Triple combination release multi-layered tablet |
| EP2997953B1 (en) | 2006-01-18 | 2018-12-26 | Intec Pharma Ltd. | Delivery device for oral intake of an agent |
| WO2007093999A1 (en) | 2006-02-15 | 2007-08-23 | Intec Pharma Ltd. | A gastro-retentive system for the delivery of macromolecules |
| WO2007106957A1 (en) | 2006-03-21 | 2007-09-27 | Laboratoires Smb S.A. | Multiple units controlled-release floating dosage forms |
| US9579227B2 (en) | 2006-03-29 | 2017-02-28 | Eat Little Inc. | Ingestible implement for weight control |
| CA2673485A1 (en) | 2007-01-15 | 2008-07-24 | Kissei Pharmaceutical Co., Ltd. | Gastric retention-type sustained-release levodopa preparation |
| AU2008282900B2 (en) * | 2007-07-27 | 2014-05-22 | Depomed, Inc. | Pulsatile gastric retentive dosage forms |
| EP2219624A2 (en) | 2007-11-08 | 2010-08-25 | Glaxo Group Limited | Pharmaceutical formulations |
| CN102149369B (zh) | 2008-04-18 | 2016-08-10 | 因泰克制药有限公司 | 卡比多巴/左旋多巴胃滞留给药 |
| EP2133071A1 (en) | 2008-06-09 | 2009-12-16 | Université de la Méditerranée | Process for making gastroretentive dosage forms |
| JP2012500230A (ja) | 2008-08-18 | 2012-01-05 | 北京天衡▲薬▼物研究院 | 胃内滞留薬物放出システム及びその製造方法と使用 |
| US20110268666A1 (en) | 2008-09-29 | 2011-11-03 | Yissum Research Development Company of the Research University of Jerusalem, Ltd. | Novel gastroretentive delivery system |
| US20110066175A1 (en) | 2009-05-07 | 2011-03-17 | Rainbow Medical Ltd. | Gastric anchor |
| EP2490677A2 (en) | 2009-10-19 | 2012-08-29 | Intec Pharma Ltd. | Novel gastroretentive dosage forms of poorly soluble drugs |
| EP3603624A1 (en) * | 2009-12-24 | 2020-02-05 | Rani Therapeutics, LLC | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| WO2011090724A2 (en) | 2009-12-29 | 2011-07-28 | Impax Laboratories, Inc. | Gastroretentive solid oral dosage forms with lipid-based low-density excipient |
| CN101919803A (zh) | 2010-07-16 | 2010-12-22 | 钟术光 | 一种控释制剂 |
| WO2012006963A1 (zh) | 2010-07-16 | 2012-01-19 | Zhong Shuguang | 在控释制剂中的聚合物增强剂 |
| US9941319B2 (en) | 2010-10-13 | 2018-04-10 | Monolithic 3D Inc. | Semiconductor and optoelectronic methods and devices |
| WO2012059815A1 (en) | 2010-11-01 | 2012-05-10 | Intec Pharma Ltd. | Accordion pill comprising levodopa for an improved treatment of parkinson's disease symptoms |
| WO2013054285A1 (en) | 2011-10-11 | 2013-04-18 | Ranbaxy Laboratories Limited | A gastroretentive dosage system and process of preparation thereof |
| KR101461332B1 (ko) | 2013-08-02 | 2014-11-13 | 삼성전기주식회사 | 센서용 검출모듈 및 이를 구비하는 각속도 센서 |
| US9016811B2 (en) | 2013-08-05 | 2015-04-28 | Concealment Solutions Inc. | Apparatus for concealing household objects |
| CA3007165A1 (en) | 2015-12-02 | 2017-06-08 | Clexio Biosciences Ltd. | Device for preparing gastroretentive dosage forms |
| CN110035718B (zh) | 2016-12-02 | 2021-04-06 | 克雷西奥生物科技有限公司 | 胃内滞留系统 |
-
2017
- 2017-12-04 CN CN201780073458.1A patent/CN110035718B/zh active Active
- 2017-12-04 WO PCT/US2017/064417 patent/WO2018102799A1/en not_active Ceased
- 2017-12-04 JP JP2019529639A patent/JP7071748B2/ja not_active Expired - Fee Related
- 2017-12-04 US US16/465,231 patent/US10737079B2/en active Active
- 2017-12-04 ES ES17835521T patent/ES2966736T3/es active Active
- 2017-12-04 IL IL266377A patent/IL266377B2/en unknown
- 2017-12-04 EP EP17835521.0A patent/EP3547974B1/en active Active
-
2020
- 2020-06-17 US US16/903,765 patent/US11577061B2/en active Active
-
2022
- 2022-11-16 US US18/055,991 patent/US20230080008A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130072869A1 (en) | 2011-09-15 | 2013-03-21 | The Johns Hopkins University | Intra-Gastric Timed-Release Drug Delivery System |
| WO2015083171A1 (en) | 2013-12-05 | 2015-06-11 | Tulip Medical Ltd. | Retentive devices and systems for in-situ release of pharmaceutical active agents |
| WO2015187746A1 (en) | 2014-06-02 | 2015-12-10 | Teva Pharmaceutical Industries Ltd. | Expandable gastroretentive dosage form |
| WO2015191920A1 (en) | 2014-06-11 | 2015-12-17 | Massachusetts Institute Of Technology | Residence structures and related methods |
Also Published As
| Publication number | Publication date |
|---|---|
| IL266377A (en) | 2019-06-30 |
| US20200030589A1 (en) | 2020-01-30 |
| CN110035718A (zh) | 2019-07-19 |
| JP2019536800A (ja) | 2019-12-19 |
| IL266377B1 (en) | 2023-06-01 |
| US20230080008A1 (en) | 2023-03-16 |
| CN110035718B (zh) | 2021-04-06 |
| IL266377B2 (en) | 2023-10-01 |
| ES2966736T3 (es) | 2024-04-24 |
| EP3547974A1 (en) | 2019-10-09 |
| WO2018102799A1 (en) | 2018-06-07 |
| EP3547974B1 (en) | 2023-11-15 |
| US10737079B2 (en) | 2020-08-11 |
| US20200376242A1 (en) | 2020-12-03 |
| US11577061B2 (en) | 2023-02-14 |
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