ES2966736T3 - Sistema de residencia gástrica - Google Patents

Sistema de residencia gástrica Download PDF

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Publication number
ES2966736T3
ES2966736T3 ES17835521T ES17835521T ES2966736T3 ES 2966736 T3 ES2966736 T3 ES 2966736T3 ES 17835521 T ES17835521 T ES 17835521T ES 17835521 T ES17835521 T ES 17835521T ES 2966736 T3 ES2966736 T3 ES 2966736T3
Authority
ES
Spain
Prior art keywords
arm
arms
erodible
expanded configuration
gastric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17835521T
Other languages
English (en)
Spanish (es)
Inventor
Menachem Avshalom Ben
Ilan Zalit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clexio Bioscience Ltd
Original Assignee
Clexio Bioscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clexio Bioscience Ltd filed Critical Clexio Bioscience Ltd
Application granted granted Critical
Publication of ES2966736T3 publication Critical patent/ES2966736T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41Devices for promoting penis erection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6871Stomach
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/50Prostheses not implantable in the body
    • A61F2002/5016Prostheses not implantable in the body adjustable
    • A61F2002/5036Prostheses not implantable in the body adjustable self-adjustable, e.g. self-learning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41Devices for promoting penis erection
    • A61F2005/412Devices for promoting penis erection by vacuum means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Soil Working Implements (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES17835521T 2016-12-02 2017-12-04 Sistema de residencia gástrica Active ES2966736T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662429095P 2016-12-02 2016-12-02
US201662430166P 2016-12-05 2016-12-05
PCT/US2017/064417 WO2018102799A1 (en) 2016-12-02 2017-12-04 Gastric residence system

Publications (1)

Publication Number Publication Date
ES2966736T3 true ES2966736T3 (es) 2024-04-24

Family

ID=61025040

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17835521T Active ES2966736T3 (es) 2016-12-02 2017-12-04 Sistema de residencia gástrica

Country Status (7)

Country Link
US (3) US10737079B2 (https=)
EP (1) EP3547974B1 (https=)
JP (1) JP7071748B2 (https=)
CN (1) CN110035718B (https=)
ES (1) ES2966736T3 (https=)
IL (1) IL266377B2 (https=)
WO (1) WO2018102799A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11576859B2 (en) 2015-10-23 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CA3006999A1 (en) * 2015-12-01 2017-06-08 Clexio Biosciences Ltd. Gastric retentive devices
WO2017100367A1 (en) 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
CN109310639A (zh) 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ,インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
CA3066658A1 (en) 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
CN111587088A (zh) * 2017-11-28 2020-08-25 麻省理工学院 胃驻留电子装置
WO2019111132A1 (en) 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Long acting gastric residence system
US12303659B2 (en) * 2018-11-15 2025-05-20 Massachusetts Institute Of Technology Thermally controlled reconfigurable medical devices
BR112021018496A2 (pt) * 2019-03-20 2021-11-30 Lyndra Therapeutics Inc Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica
AU2020242062B2 (en) * 2019-03-20 2025-12-11 Nortiva Bio, Inc. Coatings for gastric residence dosage forms
US11389398B2 (en) 2019-05-14 2022-07-19 Clexio Biosciences Ltd. Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
MX2022003803A (es) * 2019-10-01 2022-06-29 Rani Therapeutics Llc Dispositivo autodimensionable para suministrar una formulación a una pared de lumen.
US20220387312A1 (en) * 2019-11-08 2022-12-08 Lyndra Therapeutics, Inc. Gastric residence systems having arms with controlled stiffness for improved gastric residence
WO2021092486A1 (en) * 2019-11-08 2021-05-14 Lyndra, Inc. Formulations for release-rate modulating films for gastric residence systems
KR102391865B1 (ko) * 2020-04-03 2022-04-27 재단법인대구경북과학기술원 약물 전달 디바이스
IL300939A (en) * 2020-08-30 2023-04-01 Teva Pharma Devices and methods for administering a drug with retention in the stomach
IL305602A (en) * 2021-03-02 2023-11-01 Teva Pharma Retentive devices for gastrointestinal tract
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions
CA3229117A1 (en) 2021-08-19 2023-02-23 Dorit MIMROD Method of treating parkinson's disease
CN115518052B (zh) * 2022-09-22 2024-01-02 江苏集萃新型药物制剂技术研究所有限公司 胃滞留制剂及其制备方法
WO2024134599A1 (en) * 2022-12-21 2024-06-27 Teva Pharmaceutical Industries Ltd. Emptying monitoring system for gastrointestinal tract devices

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1318259A (en) 1919-10-07 Resilient wheel
AU449029B2 (en) 1969-08-28 1974-04-17 Commonwealth Scientific And Industrial Research Organisation Device for administration to ruminants
US4220153A (en) 1978-05-08 1980-09-02 Pfizer Inc. Controlled release delivery system
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
JPS6226215A (ja) * 1985-05-10 1987-02-04 メルク エンド カムパニ− インコ−ポレ−テツド 一定に制御した時間内胃中に保持できる薬剤移送装置
CA1273872A (en) 1985-05-10 1990-09-11 Larry J. Caldwell Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US5002772A (en) * 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
JPH03163011A (ja) * 1989-08-31 1991-07-15 Yamanouchi Pharmaceut Co Ltd 胃内滞留デバイス
IT1282650B1 (it) 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
DE19850309A1 (de) * 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
DE60123384T2 (de) 2000-02-04 2007-08-02 DepoMed, Inc., Menlo Park Dosierungsform des typs "hülle und kern" mit einer wirkstofffreisetzung, die sich der nullten ordnung annähert
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
AUPR839001A0 (en) * 2001-10-19 2001-11-15 Eli Lilly And Company Dosage form, device and methods of treatment
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
US20050202090A1 (en) 2002-01-03 2005-09-15 Clarke Allan J. Novel pharmaceutical dosage forms and method for producing same
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
CN1750813A (zh) * 2003-02-19 2006-03-22 尼莫科学有限公司 用于胃肠道和泌尿生殖道的自展装置
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
TW200533391A (en) * 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
IL166183A0 (en) 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
CA2613178A1 (en) 2005-07-15 2007-01-25 Kissei Pharmaceutical Co., Ltd. Sustained release preparation
US8187633B2 (en) 2005-11-03 2012-05-29 Sun Pharma Advanced Research Company Limited Controlled release coated tablets having prolonged gastric retention
CA2635313C (en) 2005-12-29 2013-12-31 Osmotica Corp. Triple combination release multi-layered tablet
EP2997953B1 (en) 2006-01-18 2018-12-26 Intec Pharma Ltd. Delivery device for oral intake of an agent
WO2007093999A1 (en) 2006-02-15 2007-08-23 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
WO2007106957A1 (en) 2006-03-21 2007-09-27 Laboratoires Smb S.A. Multiple units controlled-release floating dosage forms
US9579227B2 (en) 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
CA2673485A1 (en) 2007-01-15 2008-07-24 Kissei Pharmaceutical Co., Ltd. Gastric retention-type sustained-release levodopa preparation
AU2008282900B2 (en) * 2007-07-27 2014-05-22 Depomed, Inc. Pulsatile gastric retentive dosage forms
EP2219624A2 (en) 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
CN102149369B (zh) 2008-04-18 2016-08-10 因泰克制药有限公司 卡比多巴/左旋多巴胃滞留给药
EP2133071A1 (en) 2008-06-09 2009-12-16 Université de la Méditerranée Process for making gastroretentive dosage forms
JP2012500230A (ja) 2008-08-18 2012-01-05 北京天衡▲薬▼物研究院 胃内滞留薬物放出システム及びその製造方法と使用
US20110268666A1 (en) 2008-09-29 2011-11-03 Yissum Research Development Company of the Research University of Jerusalem, Ltd. Novel gastroretentive delivery system
US20110066175A1 (en) 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
EP2490677A2 (en) 2009-10-19 2012-08-29 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
EP3603624A1 (en) * 2009-12-24 2020-02-05 Rani Therapeutics, LLC Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
WO2011090724A2 (en) 2009-12-29 2011-07-28 Impax Laboratories, Inc. Gastroretentive solid oral dosage forms with lipid-based low-density excipient
CN101919803A (zh) 2010-07-16 2010-12-22 钟术光 一种控释制剂
WO2012006963A1 (zh) 2010-07-16 2012-01-19 Zhong Shuguang 在控释制剂中的聚合物增强剂
US9941319B2 (en) 2010-10-13 2018-04-10 Monolithic 3D Inc. Semiconductor and optoelectronic methods and devices
WO2012059815A1 (en) 2010-11-01 2012-05-10 Intec Pharma Ltd. Accordion pill comprising levodopa for an improved treatment of parkinson's disease symptoms
US20130072869A1 (en) * 2011-09-15 2013-03-21 The Johns Hopkins University Intra-Gastric Timed-Release Drug Delivery System
WO2013054285A1 (en) 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof
KR101461332B1 (ko) 2013-08-02 2014-11-13 삼성전기주식회사 센서용 검출모듈 및 이를 구비하는 각속도 센서
US9016811B2 (en) 2013-08-05 2015-04-28 Concealment Solutions Inc. Apparatus for concealing household objects
EP3091962B1 (en) * 2013-12-05 2022-06-08 Epitomee Medical Ltd. Retentive devices and systems for in-situ release of pharmaceutical active agents
WO2015187746A1 (en) 2014-06-02 2015-12-10 Teva Pharmaceutical Industries Ltd. Expandable gastroretentive dosage form
NZ727659A (en) * 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
CA3007165A1 (en) 2015-12-02 2017-06-08 Clexio Biosciences Ltd. Device for preparing gastroretentive dosage forms
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统

Also Published As

Publication number Publication date
IL266377A (en) 2019-06-30
US20200030589A1 (en) 2020-01-30
CN110035718A (zh) 2019-07-19
JP2019536800A (ja) 2019-12-19
IL266377B1 (en) 2023-06-01
US20230080008A1 (en) 2023-03-16
CN110035718B (zh) 2021-04-06
JP7071748B2 (ja) 2022-05-19
IL266377B2 (en) 2023-10-01
EP3547974A1 (en) 2019-10-09
WO2018102799A1 (en) 2018-06-07
EP3547974B1 (en) 2023-11-15
US10737079B2 (en) 2020-08-11
US20200376242A1 (en) 2020-12-03
US11577061B2 (en) 2023-02-14

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