BR112021018496A2 - Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica - Google Patents

Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica

Info

Publication number
BR112021018496A2
BR112021018496A2 BR112021018496A BR112021018496A BR112021018496A2 BR 112021018496 A2 BR112021018496 A2 BR 112021018496A2 BR 112021018496 A BR112021018496 A BR 112021018496A BR 112021018496 A BR112021018496 A BR 112021018496A BR 112021018496 A2 BR112021018496 A2 BR 112021018496A2
Authority
BR
Brazil
Prior art keywords
gastric residence
dosage forms
capsules
capsule
capsule coating
Prior art date
Application number
BR112021018496A
Other languages
English (en)
Inventor
David Altreuter
Erick Peeke
Marlene Schwarz
Megan Bishoff
Nupura Bhise
Sonia Holar
Original Assignee
Lyndra Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lyndra Therapeutics Inc filed Critical Lyndra Therapeutics Inc
Publication of BR112021018496A2 publication Critical patent/BR112021018496A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica. a presente invenção refere-se a formas de dosagem de residência gástrica compreendendo: um sistema de residência gástrica em uma configuração dobrada; uma cápsula encapsulando o sistema de residência gástrica em uma configuração dobrada; e um revestimento na cápsula, em que a forma de dosagem de residência gástrica é configurada para liberar o sistema de residência gástrica em um estômago de um paciente, permitindo que o sistema de residência gástrica assuma uma configuração aberta. o revestimento da cápsula inclui um polímero, um agente antiaderência e/ou um auxiliar de hidratação.
BR112021018496A 2019-03-20 2020-03-19 Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica BR112021018496A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962821352P 2019-03-20 2019-03-20
PCT/US2020/023704 WO2020191229A1 (en) 2019-03-20 2020-03-19 Capsules and capsule coatings for gastric residence dosage forms

Publications (1)

Publication Number Publication Date
BR112021018496A2 true BR112021018496A2 (pt) 2021-11-30

Family

ID=72519175

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021018496A BR112021018496A2 (pt) 2019-03-20 2020-03-19 Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica

Country Status (10)

Country Link
US (1) US20220160642A1 (pt)
EP (1) EP3941445A4 (pt)
JP (1) JP2022525926A (pt)
CN (1) CN113966216A (pt)
AU (1) AU2020240108A1 (pt)
BR (1) BR112021018496A2 (pt)
CA (1) CA3134049A1 (pt)
IL (1) IL286512A (pt)
MX (1) MX2021011314A (pt)
WO (1) WO2020191229A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024031023A2 (en) * 2022-08-03 2024-02-08 Lyndra Therapeutics, Inc. Metal cores for gastric residence systems

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2469205A1 (en) * 2001-12-15 2003-06-26 Spherics, Inc. Bioadhesive drug delivery system with enhanced gastric retention
WO2007002518A1 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Delayed release or extended-delayed release dosage forms of pramipexole
US9693981B2 (en) * 2008-12-04 2017-07-04 Intec Pharma Ltd. Zaleplon gastroretentive drug delivery system
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20120321706A1 (en) * 2009-10-19 2012-12-20 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
CN104684592B (zh) * 2012-08-29 2017-07-14 心脏起搏器股份公司 用于医用导线的增强的低摩擦涂层和制造方法
MX2017016509A (es) * 2015-06-17 2018-08-16 Biogen Ma Inc Particulas de dimetilfumarato y composiciones farmaceuticas de estas.
CN110022861A (zh) * 2016-09-30 2019-07-16 林德拉有限公司 用于金刚烷类药物缓释的胃驻留系统
JP7071748B2 (ja) * 2016-12-02 2022-05-19 クレキシオ バイオサイエンシーズ エルティーディー． 胃内滞留システム
US11793751B2 (en) * 2017-09-20 2023-10-24 Lyndra Therapeutics, Inc. Encapsulation of gastric residence systems
WO2019108580A1 (en) * 2017-11-28 2019-06-06 Massachusetts Institute Of Technology Gastric resident electronics

Also Published As

Publication number Publication date
IL286512A (en) 2021-10-31
CA3134049A1 (en) 2020-09-24
AU2020240108A1 (en) 2021-11-11
US20220160642A1 (en) 2022-05-26
EP3941445A4 (en) 2023-08-02
EP3941445A1 (en) 2022-01-26
MX2021011314A (es) 2021-12-10
WO2020191229A1 (en) 2020-09-24
JP2022525926A (ja) 2022-05-20
CN113966216A (zh) 2022-01-21

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