CN110035718B - 胃内滞留系统 - Google Patents

胃内滞留系统 Download PDF

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Publication number
CN110035718B
CN110035718B CN201780073458.1A CN201780073458A CN110035718B CN 110035718 B CN110035718 B CN 110035718B CN 201780073458 A CN201780073458 A CN 201780073458A CN 110035718 B CN110035718 B CN 110035718B
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China
Prior art keywords
arm
erodible
stomach
arms
gastric
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CN201780073458.1A
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Chinese (zh)
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CN110035718A (zh
Inventor
阿夫沙洛姆·本梅纳开姆
爱兰·扎利特
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Clexio Bioscience Ltd
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Clexio Bioscience Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41—Devices for promoting penis erection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6871—Stomach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/50—Prostheses not implantable in the body
    • A61F2002/5016—Prostheses not implantable in the body adjustable
    • A61F2002/5036—Prostheses not implantable in the body adjustable self-adjustable, e.g. self-learning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/41—Devices for promoting penis erection
    • A61F2005/412—Devices for promoting penis erection by vacuum means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Soil Working Implements (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201780073458.1A 2016-12-02 2017-12-04 胃内滞留系统 Active CN110035718B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662429095P 2016-12-02 2016-12-02
US62/429,095 2016-12-02
US201662430166P 2016-12-05 2016-12-05
US62/430,166 2016-12-05
PCT/US2017/064417 WO2018102799A1 (en) 2016-12-02 2017-12-04 Gastric residence system

Publications (2)

Publication Number Publication Date
CN110035718A CN110035718A (zh) 2019-07-19
CN110035718B true CN110035718B (zh) 2021-04-06

Family

ID=61025040

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780073458.1A Active CN110035718B (zh) 2016-12-02 2017-12-04 胃内滞留系统

Country Status (7)

Country Link
US (3) US10737079B2 (https=)
EP (1) EP3547974B1 (https=)
JP (1) JP7071748B2 (https=)
CN (1) CN110035718B (https=)
ES (1) ES2966736T3 (https=)
IL (1) IL266377B2 (https=)
WO (1) WO2018102799A1 (https=)

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EP3386488B1 (en) 2015-12-08 2023-09-06 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
AU2017268840B2 (en) 2016-05-27 2022-02-10 Nortiva Bio, Inc. Materials architecture for gastric residence systems
US11576866B2 (en) 2016-09-30 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
EP3547974B1 (en) 2016-12-02 2023-11-15 Clexio Biosciences Ltd. Gastric residence system
US12023406B2 (en) 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
US11684315B2 (en) * 2017-11-28 2023-06-27 Massachusetts Institute Of Technology Gastric resident electronics
JP7296084B2 (ja) * 2017-12-04 2023-06-22 クレキシオ バイオサイエンシーズ エルティーディー． 長時間作用型胃滞留システム
WO2020102650A2 (en) * 2018-11-15 2020-05-22 Massachusetts Institute Of Technology Thermally controlled reconfigurable medical devices
JP2022525482A (ja) * 2019-03-20 2022-05-16 リンドラ セラピューティクス， インコーポレイティド 胃内滞留剤形用のコーティング
MX2021011314A (es) * 2019-03-20 2021-12-10 Lyndra Therapeutics Inc Capsulas y recubrimientos de capsulas para formas de dosificacion de residencia gastrica.
EP3968980A1 (en) 2019-05-14 2022-03-23 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
AU2020360407B2 (en) * 2019-10-01 2026-04-09 Rani Therapeutics, Llc Self-sizing device for delivering a formulation to a lumen wall
CA3160660A1 (en) * 2019-11-08 2021-05-14 Lyndra Therapeutics, Inc. Formulations for release-rate modulating films for gastric residence systems
US20220387312A1 (en) * 2019-11-08 2022-12-08 Lyndra Therapeutics, Inc. Gastric residence systems having arms with controlled stiffness for improved gastric residence
KR102391865B1 (ko) 2020-04-03 2022-04-27 재단법인대구경북과학기술원 약물 전달 디바이스
US20230270575A1 (en) * 2020-08-30 2023-08-31 Teva Pharmaceutical Industries Ltd. Devices and methods for gastric retentive drug delivery
EP4301446A1 (en) * 2021-03-02 2024-01-10 Teva Pharmaceutical Industries Ltd. Retentive devices for gastrointestinal tract
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions
WO2023021480A1 (en) 2021-08-19 2023-02-23 Clexio Biosciences Ltd. Method of treating parkinson's disease
CN115518052B (zh) * 2022-09-22 2024-01-02 江苏集萃新型药物制剂技术研究所有限公司 胃滞留制剂及其制备方法
WO2024134599A1 (en) * 2022-12-21 2024-06-27 Teva Pharmaceutical Industries Ltd. Emptying monitoring system for gastrointestinal tract devices

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Publication number Publication date
EP3547974A1 (en) 2019-10-09
JP2019536800A (ja) 2019-12-19
IL266377B1 (en) 2023-06-01
US20200376242A1 (en) 2020-12-03
US10737079B2 (en) 2020-08-11
EP3547974B1 (en) 2023-11-15
WO2018102799A1 (en) 2018-06-07
IL266377A (en) 2019-06-30
US20230080008A1 (en) 2023-03-16
US20200030589A1 (en) 2020-01-30
CN110035718A (zh) 2019-07-19
IL266377B2 (en) 2023-10-01
US11577061B2 (en) 2023-02-14
JP7071748B2 (ja) 2022-05-19
ES2966736T3 (es) 2024-04-24

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