JP7054924B2 - 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 - Google Patents

免疫療法のためのｆｌｔ３指向ｃａｒ細胞 Download PDF

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JP7054924B2
JP7054924B2 JP2018534523A JP2018534523A JP7054924B2 JP 7054924 B2 JP7054924 B2 JP 7054924B2 JP 2018534523 A JP2018534523 A JP 2018534523A JP 2018534523 A JP2018534523 A JP 2018534523A JP 7054924 B2 JP7054924 B2 JP 7054924B2
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cells
flt3
car
cell
amino acid
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JP2018529380A5 (https=
JP2018529380A (ja
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ユイ、チエンホア
カリジューリ、マイケル
ディヴァイン、スティーヴン
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Cytoimmune Therapeutics Inc
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JP2018534523A 2015-09-23 2016-09-23 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 Expired - Fee Related JP7054924B2 (ja)

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JP2021189789A JP2022046461A (ja) 2015-09-23 2021-11-24 免疫療法のためのｆｌｔ３指向ｃａｒ細胞

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US201562222695P 2015-09-23 2015-09-23
US62/222,695 2015-09-23
PCT/US2016/053577 WO2017053889A2 (en) 2015-09-23 2016-09-23 Flt3 directed car cells for immunotherapy

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JP2018529380A JP2018529380A (ja) 2018-10-11
JP2018529380A5 JP2018529380A5 (https=) 2019-10-31
JP7054924B2 true JP7054924B2 (ja) 2022-04-15

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JP2021189789A Pending JP2022046461A (ja) 2015-09-23 2021-11-24 免疫療法のためのｆｌｔ３指向ｃａｒ細胞

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US (2) US10961312B2 (https=)
EP (2) EP3569244A1 (https=)
JP (2) JP7054924B2 (https=)
KR (1) KR20180053744A (https=)
CN (1) CN109310744A (https=)
AU (2) AU2016326721C1 (https=)
CA (1) CA2999037A1 (https=)
HK (1) HK1258921A1 (https=)
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AU2017271606B2 (en) 2016-05-27 2024-08-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services FLT3-specific chimeric antigen receptors and methods using same
AU2017382883B2 (en) 2016-12-21 2024-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies specific for FLT3 and uses thereof
US12163952B2 (en) 2017-02-27 2024-12-10 Juno Therapeutics, Inc. Determining toxicity risk in CAR T-cell therapy
JP7317718B2 (ja) * 2017-06-02 2023-07-31 ファイザー・インク Ｆｌｔ３を標的にするキメラ抗原受容体
AU2018275894B2 (en) 2017-06-02 2025-04-24 Juno Therapeutics, Inc. Articles of manufacture and methods for treatment using adoptive cell therapy
CN118772278A (zh) 2017-06-02 2024-10-15 辉瑞公司 Flt3的特异性抗体及其用途
JP7560356B2 (ja) * 2017-08-01 2024-10-02 ユリウス－マクシミリアン－ウニヴェルシテート・ヴュルツブルク 急性骨髄性白血病を治療するためのｆｌｔ３ ｃａｒ－ｔ細胞及びｆｌｔ３阻害剤の使用
WO2019025800A1 (en) * 2017-08-02 2019-02-07 Autolus Limited CELLS EXPRESSING A CHIMERIC ANTIGENIC RECEPTOR OR A MANIPULATED TCR AND COMPRISING A SELECTIVELY EXPRESSED SELECTIVE NUCLEOTIDE SEQUENCE
EP3704230B1 (en) 2017-11-01 2024-10-23 Juno Therapeutics, Inc. Process for generating therapeutic compositions of engineered cells
EP3707247A4 (en) * 2017-11-10 2021-11-03 Jura Bio, Inc. MAJOR HISTOCOMPATIBILITY COMPLEX CHEMERICAL RECEPTORS AND ASSOCIATED USES FOR THE TREATMENT OF AUTOIMMUNE DISEASES
CN109988759A (zh) * 2017-12-29 2019-07-09 上海细胞治疗研究院 一种在t细胞中具有高转录活性的嵌合启动子
US20190328785A1 (en) * 2018-04-30 2019-10-31 The Board Of Regents Of The University Of Oklahoma Flt3-binding chimeric antigen receptors, cells, and uses thereof
CN110305847B (zh) * 2018-07-27 2021-05-18 赛诺生（深圳）基因产业发展有限公司 一种用于治疗肿瘤的基因工程细胞
CN109134665B (zh) * 2018-08-24 2021-06-11 上海先博生物科技有限公司 一种基于单域抗体的bcma嵌合抗原受体及应用
PL3886875T3 (pl) * 2018-11-30 2024-09-09 Juno Therapeutics, Inc. Metody leczenia z wykorzystaniem adoptywnej terapii komórkowej
JP7642542B2 (ja) 2018-12-18 2025-03-10 ベーリンガー・インゲルハイム・イオ・カナダ・インコーポレイテッド Ｆｌｔ３アゴニスト抗体及びその使用
EP3962527A4 (en) 2019-04-30 2023-11-01 Senti Biosciences, Inc. CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
KR20210033436A (ko) * 2019-09-18 2021-03-26 주식회사 에스엘바이젠 신규 키메라 항원 수용체 암호화 유전자가 형질도입된 유전자 변형 nk 세포주 및 그의 용도
KR102287180B1 (ko) 2019-10-01 2021-08-09 충북대학교 산학협력단 Cd138에 특이적으로 결합하는 키메릭 항원 수용체, 이를 발현하는 면역세포 및 이의 항암 용도
JP7755597B2 (ja) * 2020-04-09 2025-10-16 オートラス リミテッド 細胞
KR20230004680A (ko) * 2020-04-17 2023-01-06 시티 오브 호프 Flt3-양성 악성 종양의 치료를 위한 flt3-표적화된 키메라 항원 수용체 변형 세포
CN111647071B (zh) * 2020-06-17 2023-05-05 深圳豪石生物科技有限公司 识别靶细胞表面抗原的t细胞受体及其组合物
CN116410315A (zh) * 2021-12-31 2023-07-11 博生吉医药科技(苏州)有限公司 一种新型靶向人flt3的嵌合抗原受体修饰的t细胞的构建及应用

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JP2011521647A (ja) 2008-05-30 2011-07-28 イムクローン・リミテッド・ライアビリティ・カンパニー 抗ｆｌｔ３抗体
JP2013515472A (ja) 2009-12-23 2013-05-09 シュニムネ ゲーエムベーハー 抗ｆｌｔ３抗体及びその使用方法
WO2014144622A2 (en) 2013-03-15 2014-09-18 Stephen Forman Cd123-specific chimeric antigen receptor redirected t cells and methods of their use
WO2015112626A1 (en) 2014-01-21 2015-07-30 June Carl H Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules

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