JP2018529380A5 - - Google Patents
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- Publication number
- JP2018529380A5 JP2018529380A5 JP2018534523A JP2018534523A JP2018529380A5 JP 2018529380 A5 JP2018529380 A5 JP 2018529380A5 JP 2018534523 A JP2018534523 A JP 2018534523A JP 2018534523 A JP2018534523 A JP 2018534523A JP 2018529380 A5 JP2018529380 A5 JP 2018529380A5
- Authority
- JP
- Japan
- Prior art keywords
- flt3
- car
- nucleic acid
- isolated
- isolated nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021189789A JP2022046461A (ja) | 2015-09-23 | 2021-11-24 | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562222695P | 2015-09-23 | 2015-09-23 | |
| US62/222,695 | 2015-09-23 | ||
| PCT/US2016/053577 WO2017053889A2 (en) | 2015-09-23 | 2016-09-23 | Flt3 directed car cells for immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021189789A Division JP2022046461A (ja) | 2015-09-23 | 2021-11-24 | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018529380A JP2018529380A (ja) | 2018-10-11 |
| JP2018529380A5 true JP2018529380A5 (https=) | 2019-10-31 |
| JP7054924B2 JP7054924B2 (ja) | 2022-04-15 |
Family
ID=58387435
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018534523A Expired - Fee Related JP7054924B2 (ja) | 2015-09-23 | 2016-09-23 | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
| JP2021189789A Pending JP2022046461A (ja) | 2015-09-23 | 2021-11-24 | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021189789A Pending JP2022046461A (ja) | 2015-09-23 | 2021-11-24 | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10961312B2 (https=) |
| EP (2) | EP3569244A1 (https=) |
| JP (2) | JP7054924B2 (https=) |
| KR (1) | KR20180053744A (https=) |
| CN (1) | CN109310744A (https=) |
| AU (2) | AU2016326721C1 (https=) |
| CA (1) | CA2999037A1 (https=) |
| HK (1) | HK1258921A1 (https=) |
| WO (1) | WO2017053889A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3569244A1 (en) * | 2015-09-23 | 2019-11-20 | CytoImmune Therapeutics, LLC | Flt3 directed car cells for immunotherapy |
| CA3025516A1 (en) | 2016-05-27 | 2017-11-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Flt3-specific chimeric antigen receptors and methods using same |
| AU2017382883B2 (en) | 2016-12-21 | 2024-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies specific for FLT3 and uses thereof |
| BR112019017767A2 (pt) | 2017-02-27 | 2020-04-07 | Juno Therapeutics Inc | composições, artigos de fabricação e métodos relacionados à dosagem em terapia celular |
| SG10202108528QA (en) * | 2017-06-02 | 2021-09-29 | Pfizer | Chimeric antigen receptors targeting flt3 |
| MY201312A (en) | 2017-06-02 | 2024-02-16 | Pfizer | Antibodies specific for flt3 and their uses |
| AU2018275894B2 (en) | 2017-06-02 | 2025-04-24 | Juno Therapeutics, Inc. | Articles of manufacture and methods for treatment using adoptive cell therapy |
| EP3661511A1 (en) * | 2017-08-01 | 2020-06-10 | Julius-Maximilians-Universität Würzburg | Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| US12258580B2 (en) | 2017-11-01 | 2025-03-25 | Juno Therapeutics, Inc. | Process for generating therapeutic compositions of engineered cells |
| KR20250067182A (ko) * | 2017-11-10 | 2025-05-14 | 주라 바이오, 인크. | 주 조직적합성 복합체-기반 키메라 수용체 및 자가면역 질병을 치료하기 위한 이의 용도 |
| CN109988759A (zh) * | 2017-12-29 | 2019-07-09 | 上海细胞治疗研究院 | 一种在t细胞中具有高转录活性的嵌合启动子 |
| US20190328785A1 (en) * | 2018-04-30 | 2019-10-31 | The Board Of Regents Of The University Of Oklahoma | Flt3-binding chimeric antigen receptors, cells, and uses thereof |
| CN110305847B (zh) * | 2018-07-27 | 2021-05-18 | 赛诺生（深圳）基因产业发展有限公司 | 一种用于治疗肿瘤的基因工程细胞 |
| CN109134665B (zh) * | 2018-08-24 | 2021-06-11 | 上海先博生物科技有限公司 | 一种基于单域抗体的bcma嵌合抗原受体及应用 |
| PT3886875T (pt) * | 2018-11-30 | 2024-06-27 | Juno Therapeutics Inc | Métodos para tratamento utilizando terapia celular adotiva |
| SG11202104352XA (en) | 2018-12-18 | 2021-05-28 | Boehringer Ingelheim Io Canada Inc | Flt3 agonist antibodies and uses thereof |
| TW202110873A (zh) | 2019-04-30 | 2021-03-16 | 美商聖堤生物科技股份有限公司 | 嵌合受體及其使用方法 |
| EP4032972A4 (en) * | 2019-09-18 | 2024-07-24 | Slbigen Inc. | GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH A GENE ENCODING A NEW CHIMERIC ANTIGEN RECEPTOR AND ITS USE |
| KR102287180B1 (ko) | 2019-10-01 | 2021-08-09 | 충북대학교 산학협력단 | Cd138에 특이적으로 결합하는 키메릭 항원 수용체, 이를 발현하는 면역세포 및 이의 항암 용도 |
| JP7755597B2 (ja) * | 2020-04-09 | 2025-10-16 | オートラス リミテッド | 細胞 |
| AU2021256053A1 (en) * | 2020-04-17 | 2022-11-10 | City Of Hope | FLT3-targeted chimeric antigen receptor modified cells for treatment of FLT3-positive malignancies |
| CN111647071B (zh) * | 2020-06-17 | 2023-05-05 | 深圳豪石生物科技有限公司 | 识别靶细胞表面抗原的t细胞受体及其组合物 |
| CN116410315A (zh) * | 2021-12-31 | 2023-07-11 | 博生吉医药科技(苏州)有限公司 | 一种新型靶向人flt3的嵌合抗原受体修饰的t细胞的构建及应用 |
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| AU7247191A (en) | 1990-01-11 | 1991-08-05 | Molecular Affinities Corporation | Production of antibodies using gene libraries |
| US5780225A (en) | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
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| CN113005091A (zh) | 2013-02-06 | 2021-06-22 | 细胞基因公司 | 具有改进特异性的修饰的t淋巴细胞 |
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| WO2015112626A1 (en) * | 2014-01-21 | 2015-07-30 | June Carl H | Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules |
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| KR20170032406A (ko) | 2014-07-15 | 2017-03-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 치료를 위한 조작된 세포 |
| CA2964958A1 (en) | 2014-10-31 | 2016-05-06 | The Trustees Of The University Of Pennsylvania | Methods and compositions for modified t cells |
| EP3234144B1 (en) | 2014-12-15 | 2020-08-26 | Bellicum Pharmaceuticals, Inc. | Methods for controlled elimination of therapeutic cells |
| HK1245827B (en) | 2014-12-15 | 2020-06-19 | Board Of Regents Of The University Of Texas System | Methods for controlled activation or elimination of therapeutic cells |
| EP3268038B1 (en) | 2015-03-09 | 2021-05-05 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to flt3 proteins |
| TWI829617B (zh) | 2015-07-31 | 2024-01-21 | 德商安美基研究（慕尼黑）公司 | Ｆｌｔ３及ｃｄ３抗體構築體 |
| US10286092B2 (en) * | 2015-08-25 | 2019-05-14 | Ucl Business Plc | Detecting a therapeutic cell |
| EP3569244A1 (en) * | 2015-09-23 | 2019-11-20 | CytoImmune Therapeutics, LLC | Flt3 directed car cells for immunotherapy |
| MY201312A (en) | 2017-06-02 | 2024-02-16 | Pfizer | Antibodies specific for flt3 and their uses |
| WO2020010284A1 (en) | 2018-07-04 | 2020-01-09 | Cytoimmune Therapeutics, LLC | Compositions and methods for immunotherapy targeting flt3, pd-1, and/or pd-l1 |
-
2016
- 2016-09-23 EP EP19170050.9A patent/EP3569244A1/en not_active Withdrawn
- 2016-09-23 CA CA2999037A patent/CA2999037A1/en not_active Abandoned
- 2016-09-23 AU AU2016326721A patent/AU2016326721C1/en not_active Ceased
- 2016-09-23 HK HK19101399.4A patent/HK1258921A1/zh unknown
- 2016-09-23 WO PCT/US2016/053577 patent/WO2017053889A2/en not_active Ceased
- 2016-09-23 CN CN201680065509.1A patent/CN109310744A/zh active Pending
- 2016-09-23 EP EP16849810.3A patent/EP3352784A4/en not_active Withdrawn
- 2016-09-23 KR KR1020187011302A patent/KR20180053744A/ko not_active Ceased
- 2016-09-23 JP JP2018534523A patent/JP7054924B2/ja not_active Expired - Fee Related
-
2017
- 2017-11-13 US US15/811,608 patent/US10961312B2/en not_active Expired - Fee Related
-
2021
- 2021-03-02 AU AU2021201329A patent/AU2021201329A1/en not_active Abandoned
- 2021-03-11 US US17/199,332 patent/US20210269534A1/en not_active Abandoned
- 2021-11-24 JP JP2021189789A patent/JP2022046461A/ja active Pending
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