JP7037884B2 - Hpv及びhpv関連疾患に対する新規のワクチン - Google Patents
Hpv及びhpv関連疾患に対する新規のワクチン Download PDFInfo
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- JP7037884B2 JP7037884B2 JP2016546462A JP2016546462A JP7037884B2 JP 7037884 B2 JP7037884 B2 JP 7037884B2 JP 2016546462 A JP2016546462 A JP 2016546462A JP 2016546462 A JP2016546462 A JP 2016546462A JP 7037884 B2 JP7037884 B2 JP 7037884B2
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- hpv
- antigen
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- antibody
- hpv16
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
- C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
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- Genetics & Genomics (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
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- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021197509A JP7536737B2 (ja) | 2014-01-13 | 2021-12-06 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2024086175A JP2024112966A (ja) | 2014-01-13 | 2024-05-28 | Hpv及びhpv関連疾患に対する新規のワクチン |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461926821P | 2014-01-13 | 2014-01-13 | |
| US61/926,821 | 2014-01-13 | ||
| US201462002718P | 2014-05-23 | 2014-05-23 | |
| US62/002,718 | 2014-05-23 | ||
| PCT/US2015/011236 WO2015106281A1 (en) | 2014-01-13 | 2015-01-13 | Novel vaccines against hpv and hpv-related diseases |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019207238A Division JP2020036612A (ja) | 2014-01-13 | 2019-11-15 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2021197509A Division JP7536737B2 (ja) | 2014-01-13 | 2021-12-06 | Hpv及びhpv関連疾患に対する新規のワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017507117A JP2017507117A (ja) | 2017-03-16 |
| JP2017507117A5 JP2017507117A5 (enExample) | 2018-02-22 |
| JP7037884B2 true JP7037884B2 (ja) | 2022-03-17 |
Family
ID=53524425
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016546462A Expired - Fee Related JP7037884B2 (ja) | 2014-01-13 | 2015-01-13 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2019207238A Pending JP2020036612A (ja) | 2014-01-13 | 2019-11-15 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2021197509A Active JP7536737B2 (ja) | 2014-01-13 | 2021-12-06 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2024086175A Pending JP2024112966A (ja) | 2014-01-13 | 2024-05-28 | Hpv及びhpv関連疾患に対する新規のワクチン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019207238A Pending JP2020036612A (ja) | 2014-01-13 | 2019-11-15 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2021197509A Active JP7536737B2 (ja) | 2014-01-13 | 2021-12-06 | Hpv及びhpv関連疾患に対する新規のワクチン |
| JP2024086175A Pending JP2024112966A (ja) | 2014-01-13 | 2024-05-28 | Hpv及びhpv関連疾患に対する新規のワクチン |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US10286058B2 (enExample) |
| EP (2) | EP3094652B1 (enExample) |
| JP (4) | JP7037884B2 (enExample) |
| CN (2) | CN106103483A (enExample) |
| AU (1) | AU2015204503B2 (enExample) |
| CA (1) | CA2936833A1 (enExample) |
| IL (1) | IL246759A0 (enExample) |
| WO (1) | WO2015106281A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022081468A (ja) * | 2014-01-13 | 2022-05-31 | ベイラー リサーチ インスティテュート | Hpv及びhpv関連疾患に対する新規のワクチン |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012520073A (ja) * | 2009-03-10 | 2012-09-06 | ベイラー リサーチ インスティテュート | 抗原提示細胞ターゲティングワクチン |
| CN105837691B (zh) * | 2009-03-10 | 2021-06-29 | 贝勒研究院 | 靶向抗原呈递细胞的癌症疫苗 |
| WO2017015504A1 (en) * | 2015-07-21 | 2017-01-26 | Scheibel Steven Frederick | Treatment and prevention of anal conditions |
| AU2017223970B2 (en) * | 2016-02-27 | 2022-01-27 | Hpvvax, Llc | Method and composition for treating cancer or skin lesion using a vaccine |
| NZ750976A (en) | 2016-09-19 | 2023-01-27 | I Mab Biopharma Hangzhou Co Ltd | Anti-gm-csf antibodies and uses thereof |
| ES2883720T3 (es) * | 2016-11-07 | 2021-12-09 | Us Health | Desarrollo de epítopos agonistas del virus del papiloma humano |
| CN109021097A (zh) * | 2017-06-08 | 2018-12-18 | 艾托金生物医药(苏州)有限公司 | 一种识别hpv18和/或hpv45的单克隆抗体及其应用 |
| CN109384848A (zh) * | 2017-08-10 | 2019-02-26 | 深圳市雅臣智能生物工程有限公司 | 抗人乳头瘤病毒和抗cd人源化的双靶向抗体及其组合物、制备方法和应用 |
| AU2019231654B2 (en) * | 2018-03-06 | 2025-12-11 | Precigen, Inc. | Human papillomavirus vaccines and uses of the same |
| WO2020193718A1 (en) * | 2019-03-27 | 2020-10-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Recombinant proteins with cd40 activating properties |
| CN110054686A (zh) * | 2019-04-17 | 2019-07-26 | 深圳市雅臣智能生物工程有限公司 | 抗广谱HPV-L1、E6/E7-IgY及其小分子抗体以及应用 |
| CN111620955B (zh) * | 2020-07-01 | 2022-11-08 | 北京康爱瑞浩细胞技术有限公司 | 一种多靶位复合抗原及其应用 |
| CA3205280A1 (en) * | 2020-12-23 | 2022-06-30 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells |
| MX2023008986A (es) * | 2021-01-29 | 2023-08-15 | Inst Nat Sante Rech Med | Polipeptidos antigenicos de chlamydia trachomatis y usos de los mismos con fines de vacuna. |
| KR102514849B1 (ko) * | 2021-10-28 | 2023-03-28 | 전남대학교산학협력단 | 수지상 세포를 표적하는 신규한 펩타이드, 및 이를 포함하는 암 치료용 조성물 |
| CN114573698B (zh) * | 2022-03-16 | 2023-01-06 | 沈阳三生制药有限责任公司 | 一种FcRn抗原结合蛋白及其制备方法和应用 |
| CN116621971B (zh) * | 2022-12-16 | 2025-03-25 | 生物岛实验室 | Hpv18亚型的纳米抗体及其应用 |
| WO2024145863A1 (en) * | 2023-01-05 | 2024-07-11 | Virogin Biotech (Shanghai) Ltd. | A NOVEL mRNA VACCINE FOR THE TREATMENT AND PREVENTION OF HPV-ASSOCIATED LESIONS AND TUMORS |
| CN119215159A (zh) * | 2024-09-24 | 2024-12-31 | 深圳市格茵莱生物科技有限公司 | 树突状细胞多抗原负载免疫治疗方法 |
Citations (7)
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| WO2010104747A2 (en) | 2009-03-10 | 2010-09-16 | Baylor Research Institute | Antigen presenting cell targeted vaccines |
| JP2011502486A (ja) | 2007-11-02 | 2011-01-27 | ザ ジョンズ ホプキンス ユニバーシティ | ヒトパピローマウイルス感染症の治療又は予防のための複数型hpvペプチド組成物及び方法 |
| JP2012501323A (ja) | 2008-08-29 | 2012-01-19 | アカデミシュ ジーケンハウス ライデン ハー.オー.デー.エン. ルムク | 対象の腫瘍流入領域リンパ節へのcd40アゴニストの送達 |
| JP2012520074A (ja) | 2009-03-10 | 2012-09-06 | ベイラー リサーチ インスティテュート | 抗cd40抗体及びその使用 |
| JP2012525410A (ja) | 2009-04-28 | 2012-10-22 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 抗原特異的な免疫応答を高めるための組成物及び方法 |
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| EP3094652B1 (en) | 2021-09-29 |
| CN106103483A (zh) | 2016-11-09 |
| EP3992210A1 (en) | 2022-05-04 |
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