JP7020924B2 - IgG4κ/λハイブリッド抗体の検出によってIgG4関連疾患を検出またはモニタリングする方法 - Google Patents
IgG4κ/λハイブリッド抗体の検出によってIgG4関連疾患を検出またはモニタリングする方法 Download PDFInfo
- Publication number
- JP7020924B2 JP7020924B2 JP2017568262A JP2017568262A JP7020924B2 JP 7020924 B2 JP7020924 B2 JP 7020924B2 JP 2017568262 A JP2017568262 A JP 2017568262A JP 2017568262 A JP2017568262 A JP 2017568262A JP 7020924 B2 JP7020924 B2 JP 7020924B2
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- Prior art keywords
- igg4
- light chain
- bound
- specific
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1511364.0A GB201511364D0 (en) | 2015-06-29 | 2015-06-29 | Method of detecting or monitoring an IgG4-related disease |
| GB1511364.0 | 2015-06-29 | ||
| PCT/GB2016/051939 WO2017001841A1 (en) | 2015-06-29 | 2016-06-28 | Method of detecting or monitoring an igg4-related disease by detecting igg4 kappa/lambda hybrid antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018519525A JP2018519525A (ja) | 2018-07-19 |
| JP2018519525A5 JP2018519525A5 (https=) | 2020-12-03 |
| JP7020924B2 true JP7020924B2 (ja) | 2022-02-16 |
Family
ID=53872357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568262A Active JP7020924B2 (ja) | 2015-06-29 | 2016-06-28 | IgG4κ/λハイブリッド抗体の検出によってIgG4関連疾患を検出またはモニタリングする方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3314267A1 (https=) |
| JP (1) | JP7020924B2 (https=) |
| GB (1) | GB201511364D0 (https=) |
| WO (1) | WO2017001841A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114324884A (zh) * | 2020-09-30 | 2022-04-12 | 南京金斯瑞生物科技有限公司 | 一种不依赖于抗体类型的抗体检测方法及其应用 |
| CN112198319A (zh) * | 2020-10-23 | 2021-01-08 | 安徽伊普诺康生物技术股份有限公司 | 一种稳定性增强的人免疫球蛋白g4试剂盒 |
| CN118731344B (zh) * | 2024-05-28 | 2025-12-30 | 北京华放天实生物制药有限责任公司 | 一种对双抗生产重组细胞株进行高通量错配检测的方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005249592A (ja) | 2004-03-04 | 2005-09-15 | Yamasa Shoyu Co Ltd | 遊離ヒトイムノグロブリン軽鎖の測定法及びキット |
| JP2008528995A (ja) | 2005-01-27 | 2008-07-31 | ザ バインディング サイト リミテッド | 悪性プラズマ細胞疾患の検出又はモニタリング方法 |
| US20110008806A1 (en) | 2008-01-02 | 2011-01-13 | Fundação De Amparoá Pesquisa Do Estado De Minas Gerais - Fapemig | Method and kit for quantifying of allergen-specific human igg subclasses for the control and attendance of specific immunotherapy |
| JP2012050369A (ja) | 2010-08-31 | 2012-03-15 | Kanazawa Medical Univ | IgG4関連疾患診断用マーカー及びその利用 |
-
2015
- 2015-06-29 GB GBGB1511364.0A patent/GB201511364D0/en not_active Ceased
-
2016
- 2016-06-28 EP EP16736564.2A patent/EP3314267A1/en active Pending
- 2016-06-28 WO PCT/GB2016/051939 patent/WO2017001841A1/en not_active Ceased
- 2016-06-28 JP JP2017568262A patent/JP7020924B2/ja active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005249592A (ja) | 2004-03-04 | 2005-09-15 | Yamasa Shoyu Co Ltd | 遊離ヒトイムノグロブリン軽鎖の測定法及びキット |
| JP2008528995A (ja) | 2005-01-27 | 2008-07-31 | ザ バインディング サイト リミテッド | 悪性プラズマ細胞疾患の検出又はモニタリング方法 |
| US20110008806A1 (en) | 2008-01-02 | 2011-01-13 | Fundação De Amparoá Pesquisa Do Estado De Minas Gerais - Fapemig | Method and kit for quantifying of allergen-specific human igg subclasses for the control and attendance of specific immunotherapy |
| JP2012050369A (ja) | 2010-08-31 | 2012-03-15 | Kanazawa Medical Univ | IgG4関連疾患診断用マーカー及びその利用 |
Non-Patent Citations (4)
| Title |
|---|
| Elizabeth Young, Emma Lock, et al.,Estimaton of polyclonal IgG4 hybrids in normal human serum,Immunology,英国,2014年07月10日,vol. 142, no. 3, 406-413 |
| Evgenii A. Lekchnov, Sergey E. Sedykh, et al.,Human placenta: relative content of antibodies of different classes and subclasses (IgG1-IgG4) containing lambda- and kappa-light chains and chimeric lambda-kappa-immunoglobulins,International Immunology,日本,2015年06月01日,Vol. 27, No. 6, pp. 297-306 |
| Mahmud Abo Salook, Carlos Benbassat, et al.,IgG4-related thyroiditis: a case report and review of literature,Endocrinology, Diabetes & Metabolism Case Reports,米国,2014年,2014: 140037 |
| Shapiro RI, Plavina T, et al.,Development and validation of immunoassays to quantify the half-antibody exhange of an IgG4 antibody, natalizumab (Tysabri) with endogenous IgG4,Journal of Pharmaceutical and Biomedical Analyis,米国,2011年04月01日,vol. 55, issue 1, 168-175 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB201511364D0 (en) | 2015-08-12 |
| WO2017001841A1 (en) | 2017-01-05 |
| JP2018519525A (ja) | 2018-07-19 |
| EP3314267A1 (en) | 2018-05-02 |
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