JP2018519525A5 - - Google Patents
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- Publication number
- JP2018519525A5 JP2018519525A5 JP2017568262A JP2017568262A JP2018519525A5 JP 2018519525 A5 JP2018519525 A5 JP 2018519525A5 JP 2017568262 A JP2017568262 A JP 2017568262A JP 2017568262 A JP2017568262 A JP 2017568262A JP 2018519525 A5 JP2018519525 A5 JP 2018519525A5
- Authority
- JP
- Japan
- Prior art keywords
- light chain
- heavy chain
- bound
- igg4
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011230 binding agent Substances 0.000 claims description 60
- 108060003951 Immunoglobulin Proteins 0.000 claims description 24
- 102000018358 immunoglobulin Human genes 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 24
- 238000001514 detection method Methods 0.000 claims description 8
- 229940072221 immunoglobulins Drugs 0.000 claims description 7
- 208000021330 IgG4-related disease Diseases 0.000 claims description 4
- 208000037142 IgG4-related systemic disease Diseases 0.000 claims description 4
- 208000004187 Immunoglobulin G4-Related Disease Diseases 0.000 claims description 4
- 239000000758 substrate Substances 0.000 claims description 4
- 238000012544 monitoring process Methods 0.000 claims description 2
- 238000003149 assay kit Methods 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 238000000159 protein binding assay Methods 0.000 claims 3
- 238000002965 ELISA Methods 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- -1 antibody Proteins 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 238000012512 characterization method Methods 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 210000002751 lymph Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1511364.0A GB201511364D0 (en) | 2015-06-29 | 2015-06-29 | Method of detecting or monitoring an IgG4-related disease |
| GB1511364.0 | 2015-06-29 | ||
| PCT/GB2016/051939 WO2017001841A1 (en) | 2015-06-29 | 2016-06-28 | Method of detecting or monitoring an igg4-related disease by detecting igg4 kappa/lambda hybrid antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018519525A JP2018519525A (ja) | 2018-07-19 |
| JP2018519525A5 true JP2018519525A5 (https=) | 2020-12-03 |
| JP7020924B2 JP7020924B2 (ja) | 2022-02-16 |
Family
ID=53872357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568262A Active JP7020924B2 (ja) | 2015-06-29 | 2016-06-28 | ＩｇＧ４κ／λハイブリッド抗体の検出によってＩｇＧ４関連疾患を検出またはモニタリングする方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3314267A1 (https=) |
| JP (1) | JP7020924B2 (https=) |
| GB (1) | GB201511364D0 (https=) |
| WO (1) | WO2017001841A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114324884A (zh) * | 2020-09-30 | 2022-04-12 | 南京金斯瑞生物科技有限公司 | 一种不依赖于抗体类型的抗体检测方法及其应用 |
| CN112198319A (zh) * | 2020-10-23 | 2021-01-08 | 安徽伊普诺康生物技术股份有限公司 | 一种稳定性增强的人免疫球蛋白g4试剂盒 |
| CN118731344B (zh) * | 2024-05-28 | 2025-12-30 | 北京华放天实生物制药有限责任公司 | 一种对双抗生产重组细胞株进行高通量错配检测的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4438455B2 (ja) * | 2004-03-04 | 2010-03-24 | ヤマサ醤油株式会社 | 遊離ヒトイムノグロブリン軽鎖の測定法及びキット |
| GB0501741D0 (en) * | 2005-01-27 | 2005-03-02 | Binding Site The Ltd | Antibody |
| BRPI0800612A2 (pt) * | 2008-01-02 | 2009-08-25 | Fundacao Fapemig | método e kit para a quantificação de subclasses de igg humanas especìficas a alérgenos para o acompanhamento da imunoterapia especìfica |
| JP5704684B2 (ja) * | 2010-08-31 | 2015-04-22 | 学校法人金沢医科大学 | ＩｇＧ４関連疾患診断用マーカー及びその利用 |
-
2015
- 2015-06-29 GB GBGB1511364.0A patent/GB201511364D0/en not_active Ceased
-
2016
- 2016-06-28 EP EP16736564.2A patent/EP3314267A1/en active Pending
- 2016-06-28 WO PCT/GB2016/051939 patent/WO2017001841A1/en not_active Ceased
- 2016-06-28 JP JP2017568262A patent/JP7020924B2/ja active Active
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