JP2006526027A5 - - Google Patents
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- Publication number
- JP2006526027A5 JP2006526027A5 JP2006515229A JP2006515229A JP2006526027A5 JP 2006526027 A5 JP2006526027 A5 JP 2006526027A5 JP 2006515229 A JP2006515229 A JP 2006515229A JP 2006515229 A JP2006515229 A JP 2006515229A JP 2006526027 A5 JP2006526027 A5 JP 2006526027A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- autoantibody
- autoantibodies
- oxidizing agent
- biological fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 20
- 239000013060 biological fluid Substances 0.000 claims 12
- 239000007800 oxidant agent Substances 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 11
- 210000004369 blood Anatomy 0.000 claims 8
- 239000008280 blood Substances 0.000 claims 8
- 239000000284 extract Substances 0.000 claims 7
- 210000002381 plasma Anatomy 0.000 claims 7
- 210000002966 serum Anatomy 0.000 claims 7
- 239000007788 liquid Substances 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 230000004075 alteration Effects 0.000 claims 2
- 229930002875 chlorophyll Natural products 0.000 claims 2
- 235000019804 chlorophyll Nutrition 0.000 claims 2
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical group C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims 2
- BTIJJDXEELBZFS-QDUVMHSLSA-K hemin Chemical group CC1=C(CCC(O)=O)C(C=C2C(CCC(O)=O)=C(C)\C(N2[Fe](Cl)N23)=C\4)=N\C1=C/C2=C(C)C(C=C)=C3\C=C/1C(C)=C(C=C)C/4=N\1 BTIJJDXEELBZFS-QDUVMHSLSA-K 0.000 claims 2
- 229940025294 hemin Drugs 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 1
- 210000004700 fetal blood Anatomy 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 230000002441 reversible effect Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47660703P | 2003-06-09 | 2003-06-09 | |
| PCT/US2004/017889 WO2004111608A2 (en) | 2003-06-09 | 2004-06-09 | Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006526027A JP2006526027A (ja) | 2006-11-16 |
| JP2006526027A5 true JP2006526027A5 (https=) | 2009-11-26 |
| JP4662557B2 JP4662557B2 (ja) | 2011-03-30 |
Family
ID=33551622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515229A Expired - Fee Related JP4662557B2 (ja) | 2003-06-09 | 2004-06-09 | 酸化還元反応による血漿タンパク質の結合特異性の改変方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US7368542B2 (https=) |
| EP (1) | EP1631314B1 (https=) |
| JP (1) | JP4662557B2 (https=) |
| CN (1) | CN1832756A (https=) |
| AT (1) | ATE518886T1 (https=) |
| AU (1) | AU2004248155B2 (https=) |
| BR (1) | BRPI0411103B1 (https=) |
| CA (1) | CA2524325C (https=) |
| WO (1) | WO2004111608A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7892751B2 (en) | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
| US9557325B2 (en) * | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| AU2004248155B2 (en) | 2003-06-09 | 2008-10-23 | Redox-Reactive Reagents L.L.C. | Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions |
| JP5553963B2 (ja) * | 2004-10-22 | 2014-07-23 | アムジエン・インコーポレーテツド | 組換え抗体をリフォールディングする方法 |
| KR101322247B1 (ko) * | 2007-09-06 | 2013-10-25 | 삼성전자주식회사 | 진공청소기용 흡입브러시 및 그 높이조절방법 |
| MX2010002683A (es) * | 2007-09-14 | 2010-03-26 | Amgen Inc | Poblaciones de anticuerpos homogeneos. |
| US7989596B2 (en) * | 2007-09-19 | 2011-08-02 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of monoclonal antibodies by oxidation-reduction reactions |
| JP5565607B2 (ja) | 2009-07-15 | 2014-08-06 | 国立大学法人 東京大学 | 敗血症又は多臓器不全の予後診断方法及び予後診断用キット |
| US20130040844A1 (en) * | 2010-01-28 | 2013-02-14 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers of aging for detection and treatment of disorders |
| US20160208011A1 (en) | 2010-01-28 | 2016-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same |
| WO2017120461A1 (en) | 2016-01-08 | 2017-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same |
| US9161968B2 (en) | 2011-04-08 | 2015-10-20 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists |
| EP2836845B1 (en) | 2012-04-13 | 2018-05-09 | DiabetOmics, Inc. | Maternal biomarkers for gestational diabetes |
| US20150210753A1 (en) | 2012-07-26 | 2015-07-30 | Momenta Pharmaceuticals, Inc. | Glycoproteins with anti-inflammatory properties |
| WO2014186310A1 (en) | 2013-05-13 | 2014-11-20 | Momenta Pharmaceuticals, Inc. | Methods for the treatment of neurodegeneration |
| WO2014193973A2 (en) | 2013-05-28 | 2014-12-04 | Dcb-Usa Llc | Antibody locker for the inactivation of protein drug |
| US10905779B2 (en) | 2013-12-09 | 2021-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for screening human blood products comprising plasma using immunocompromised rodent models |
| MX2016007492A (es) | 2013-12-09 | 2017-03-06 | Univ Leland Stanford Junior | Métodos y composiciones para el tratamiento de afecciones asociadas con el envejecimiento. |
| KR20240025721A (ko) | 2015-06-15 | 2024-02-27 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 노화와 연관된 질환을 치료하기 위한 방법 및 조성물 |
| KR20180032489A (ko) * | 2016-09-22 | 2018-03-30 | 아주대학교산학협력단 | 액상 플라즈마를 이용한 건선의 예방 또는 치료 방법 |
| US11583689B2 (en) * | 2016-09-22 | 2023-02-21 | Ajou University Industry-Academic Cooperation Foundation | Composition for atopy or psoriasis treatment comprising liquid type plasma |
| KR20180032490A (ko) * | 2016-09-22 | 2018-03-30 | 아주대학교산학협력단 | 액상 플라즈마를 이용한 아토피성 피부염의 예방 또는 치료 방법 |
| KR101933920B1 (ko) | 2016-09-22 | 2018-12-31 | 아주대학교 산학협력단 | 액상 플라즈마를 이용한 비만의 예방 또는 치료 방법 |
| EA201991353A1 (ru) | 2016-12-09 | 2019-11-29 | Двухвалентные антитела, маскированные спирализованными спиралями | |
| WO2019054836A2 (ko) | 2017-09-18 | 2019-03-21 | 아주대학교산학협력단 | 액상 플라즈마를 포함하는 피부 진정용 조성물 |
| EP3955962A4 (en) * | 2019-04-18 | 2022-12-14 | Momenta Pharmaceuticals, Inc. | SIALYLATED GLYCOPROTEINS |
| EP3756648A1 (en) * | 2019-06-27 | 2020-12-30 | Imnate Sarl | Improved vaccine formulations |
| TR202016418A2 (tr) * | 2020-10-14 | 2022-04-21 | Serkan Tunc | Kan plazmasinin üzeri̇nden elektri̇k akiminin geçi̇ri̇lmesi̇yle i̇çeri̇si̇nde ölü bakteri̇, parazi̇t vi̇rüs vb. kalintilarin oluştuğu yeni̇ plazmanin canli vücuduna serum olarak veri̇lmesi̇yle bağişiklik geli̇şti̇rme yöntemi̇ |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632980A (en) * | 1985-04-03 | 1986-12-30 | Immunologics | Ozone decontamination of blood and blood products |
| US4703001A (en) * | 1985-10-23 | 1987-10-27 | Synbiotics, Corporation | Immunoassay for the detection of serum analytes using pH dependent chastropic acids |
| US4950612A (en) * | 1987-12-16 | 1990-08-21 | Microgenics Corporation | Peroxy acid pretreatment in vitamin B12 assay |
| DE3880477T2 (de) * | 1988-02-22 | 1993-09-16 | Fina Research | Katalytisches einstufenverfahren zur direkten umwandlung von polysacchariden in mehrwertige alkohole. |
| US5061790A (en) * | 1989-07-10 | 1991-10-29 | Molecular Diagnostics, Inc. | Oxidative denaturation of protein analytes |
| US5980954A (en) * | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| US6660267B1 (en) * | 1992-12-21 | 2003-12-09 | Promega Corporation | Prevention and treatment of sepsis |
| US5880954A (en) * | 1995-12-04 | 1999-03-09 | Thomson; Robert | Continous real time safety-related control system |
| AU703814B2 (en) * | 1995-12-04 | 1999-04-01 | Wyeth | Antioxidant |
| US5939394A (en) * | 1996-01-18 | 1999-08-17 | Fleming & Company | Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections |
| FR2794461B1 (fr) * | 1999-06-07 | 2004-01-23 | Lab Francais Du Fractionnement | Procede de preparation de nouvelles fractions d'ig humaines possedant une activite immunomodulatrice |
| FR2822238B1 (fr) | 2001-03-16 | 2003-08-29 | Gemac | Methode et trousse pour le suivi des maladies neurodegeneratives |
| US20040101909A1 (en) | 2002-08-20 | 2004-05-27 | Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 | Purification of polyreactive autoantibodies and uses thereof |
| US9557325B2 (en) | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| AU2004248155B2 (en) | 2003-06-09 | 2008-10-23 | Redox-Reactive Reagents L.L.C. | Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions |
-
2004
- 2004-06-09 AU AU2004248155A patent/AU2004248155B2/en not_active Ceased
- 2004-06-09 JP JP2006515229A patent/JP4662557B2/ja not_active Expired - Fee Related
- 2004-06-09 US US10/863,365 patent/US7368542B2/en not_active Expired - Lifetime
- 2004-06-09 CA CA2524325A patent/CA2524325C/en not_active Expired - Fee Related
- 2004-06-09 WO PCT/US2004/017889 patent/WO2004111608A2/en not_active Ceased
- 2004-06-09 EP EP20040754487 patent/EP1631314B1/en not_active Expired - Lifetime
- 2004-06-09 AT AT04754487T patent/ATE518886T1/de not_active IP Right Cessation
- 2004-06-09 BR BRPI0411103A patent/BRPI0411103B1/pt not_active IP Right Cessation
- 2004-06-09 CN CNA2004800159879A patent/CN1832756A/zh active Pending
-
2008
- 2008-04-23 US US12/107,819 patent/US8334146B2/en not_active Expired - Fee Related
-
2012
- 2012-12-12 US US13/712,151 patent/US9169317B2/en not_active Expired - Fee Related
-
2015
- 2015-10-27 US US14/923,945 patent/US10072068B2/en not_active Expired - Fee Related
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