JP6980674B2 - ヒト化ｔｍｐｒｓｓ遺伝子を有する齧歯類 - Google Patents

ヒト化ｔｍｐｒｓｓ遺伝子を有する齧歯類 Download PDF

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JP6980674B2
JP6980674B2 JP2018545182A JP2018545182A JP6980674B2 JP 6980674 B2 JP6980674 B2 JP 6980674B2 JP 2018545182 A JP2018545182 A JP 2018545182A JP 2018545182 A JP2018545182 A JP 2018545182A JP 6980674 B2 JP6980674 B2 JP 6980674B2
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gene
rodent
humanized
human
tmprss
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JP2019511918A5 (cg-RX-API-DMAC7.html
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ンガンボ、リサ パーセル
オー． ムヒカ、アレクサンダー
タン、ヤジュン
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Regeneron Pharmaceuticals Inc
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    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
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    • A01K67/027—New or modified breeds of vertebrates
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    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2267/00—Animals characterised by purpose
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    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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JP2018545182A 2016-02-29 2017-02-27 ヒト化ｔｍｐｒｓｓ遺伝子を有する齧歯類 Active JP6980674B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662301023P 2016-02-29 2016-02-29
US62/301,023 2016-02-29
PCT/US2017/019574 WO2017151453A1 (en) 2016-02-29 2017-02-27 Rodents having a humanized tmprss gene

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JP2019511918A JP2019511918A (ja) 2019-05-09
JP2019511918A5 JP2019511918A5 (cg-RX-API-DMAC7.html) 2020-04-09
JP6980674B2 true JP6980674B2 (ja) 2021-12-15

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US (5) US10070632B2 (cg-RX-API-DMAC7.html)
EP (2) EP3895529A1 (cg-RX-API-DMAC7.html)
JP (1) JP6980674B2 (cg-RX-API-DMAC7.html)
KR (2) KR102493894B1 (cg-RX-API-DMAC7.html)
CN (1) CN109068621B (cg-RX-API-DMAC7.html)
AU (1) AU2017228293B2 (cg-RX-API-DMAC7.html)
CA (1) CA3014645C (cg-RX-API-DMAC7.html)
DK (1) DK3422845T3 (cg-RX-API-DMAC7.html)
ES (1) ES2886958T3 (cg-RX-API-DMAC7.html)
IL (1) IL261139B (cg-RX-API-DMAC7.html)
PT (1) PT3422845T (cg-RX-API-DMAC7.html)
RU (1) RU2749715C2 (cg-RX-API-DMAC7.html)
SG (2) SG11201807038UA (cg-RX-API-DMAC7.html)
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CN107666828B (zh) 2015-04-06 2021-04-09 瑞泽恩制药公司 非人动物中的人源化t细胞介导的免疫应答
JP6997708B2 (ja) 2015-11-20 2022-02-04 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒト化されたｌｙｍｐｈｏｃｙｔｅ－ａｃｔｉｖａｔｉｏｎ ｇｅｎｅ ３遺伝子を有する非ヒト動物
AU2017228293B2 (en) * 2016-02-29 2023-05-25 Regeneron Pharmaceuticals, Inc. Rodents having a humanized Tmprss gene
KR101693243B1 (ko) 2016-06-15 2017-01-05 재단법인 한국파스퇴르연구소 인플루엔자 바이러스의 복제에 관여하는 신규 인간 유전자 및 이의 용도

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