JP6977029B2 - レット症候群を治療するためのプリドピジンの使用 - Google Patents

レット症候群を治療するためのプリドピジンの使用 Download PDF

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JP6977029B2
JP6977029B2 JP2019514217A JP2019514217A JP6977029B2 JP 6977029 B2 JP6977029 B2 JP 6977029B2 JP 2019514217 A JP2019514217 A JP 2019514217A JP 2019514217 A JP2019514217 A JP 2019514217A JP 6977029 B2 JP6977029 B2 JP 6977029B2
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predopidine
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mecp2
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JP2019532926A5 (enExample
JP2019532926A (ja
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ゲヴァ、ミカル
ローファー、ラルフ
ヘイデン、マイケル
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プリレニア ニューロセラピューティクス リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
JP2019514217A 2016-09-16 2017-09-15 レット症候群を治療するためのプリドピジンの使用 Active JP6977029B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662395854P 2016-09-16 2016-09-16
US62/395,854 2016-09-16
PCT/US2017/051803 WO2018053280A1 (en) 2016-09-16 2017-09-15 Use of pridopidine for treating rett syndrome

Publications (3)

Publication Number Publication Date
JP2019532926A JP2019532926A (ja) 2019-11-14
JP2019532926A5 JP2019532926A5 (enExample) 2019-12-26
JP6977029B2 true JP6977029B2 (ja) 2021-12-08

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JP2019514217A Active JP6977029B2 (ja) 2016-09-16 2017-09-15 レット症候群を治療するためのプリドピジンの使用

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EP (2) EP3512506B1 (enExample)
JP (1) JP6977029B2 (enExample)
CN (1) CN109982686A (enExample)
AU (1) AU2017326013B2 (enExample)
BR (1) BR112019005040A2 (enExample)
CA (1) CA3036984C (enExample)
DK (2) DK3512506T3 (enExample)
ES (2) ES2986807T3 (enExample)
HU (1) HUE058314T2 (enExample)
IL (1) IL265342B2 (enExample)
MX (1) MX388845B (enExample)
PL (2) PL3512506T3 (enExample)
WO (1) WO2018053280A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014205229A1 (en) 2013-06-21 2014-12-24 IVAX International GmbH Use of high dose pridopidine for treating huntington's disease
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
BR112019003731A2 (pt) 2016-08-24 2019-07-16 Prilenia Therapeutics Dev Ltd aplicação de pridopidina para tratamento de distonias
JP6912574B2 (ja) 2016-08-24 2021-08-04 プリレニア ニューロセラピューティクス リミテッド 機能低下を治療するためのプリドピジンの使用
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
ES2986807T3 (es) 2016-09-16 2024-11-12 Prilenia Neurotherapeutics Ltd Pridopidina para su uso en el tratamiento del síndrome de Rett
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
US12357624B2 (en) 2019-02-04 2025-07-15 Prilenia Neurotherapeutics Ltd. Low dose pridopidine for Parkinson's Disease and other diseases associated with parkinsonism
CN116472043A (zh) * 2020-10-20 2023-07-21 普瑞尼亚神经治疗有限公司 普利多匹定和类似物用于治疗焦虑和抑郁的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
AU2005293754B2 (en) 2004-10-13 2011-07-21 Teva Pharmaceuticals International Gmbh Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-N-propyl-piperidine
EA201390332A1 (ru) 2010-09-03 2013-08-30 Ивакс Интернэшнл Гмбх Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов
MX347209B (es) * 2011-12-08 2017-04-19 Teva Pharmaceuticals Int Gmbh La sal de bromhidrato de pridopidina.
EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения
WO2014205229A1 (en) 2013-06-21 2014-12-24 IVAX International GmbH Use of high dose pridopidine for treating huntington's disease
HUE058288T2 (hu) 2014-01-22 2022-07-28 Prilenia Neurotherapeutics Ltd Pridopidin módosított hatóanyag-leadású készítményei
WO2016138135A1 (en) * 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease
EP3590512A1 (en) * 2015-02-25 2020-01-08 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat epilepsy
ES2986807T3 (es) 2016-09-16 2024-11-12 Prilenia Neurotherapeutics Ltd Pridopidina para su uso en el tratamiento del síndrome de Rett

Also Published As

Publication number Publication date
BR112019005040A2 (pt) 2019-07-16
AU2017326013B2 (en) 2020-12-24
MX388845B (es) 2025-03-20
EP3512506A4 (en) 2020-05-27
IL265342B2 (en) 2023-06-01
CA3036984A1 (en) 2018-03-22
EP3512506A1 (en) 2019-07-24
CA3036984C (en) 2023-07-18
ES2986807T3 (es) 2024-11-12
AU2017326013A1 (en) 2019-04-11
JP2019532926A (ja) 2019-11-14
EP4005570B1 (en) 2024-05-15
DK4005570T3 (da) 2024-08-19
WO2018053280A1 (en) 2018-03-22
CN109982686A (zh) 2019-07-05
IL265342A (en) 2019-05-30
HUE058314T2 (hu) 2022-07-28
EP4005570A1 (en) 2022-06-01
ES2909557T3 (es) 2022-05-09
PL4005570T3 (pl) 2024-09-23
PL3512506T3 (pl) 2022-05-30
EP3512506B1 (en) 2022-01-26
MX2019003069A (es) 2019-09-02
DK3512506T3 (da) 2022-04-19

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