AU2017326013B2 - Use of pridopidine for treating Rett syndrome - Google Patents

Use of pridopidine for treating Rett syndrome Download PDF

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Publication number
AU2017326013B2
AU2017326013B2 AU2017326013A AU2017326013A AU2017326013B2 AU 2017326013 B2 AU2017326013 B2 AU 2017326013B2 AU 2017326013 A AU2017326013 A AU 2017326013A AU 2017326013 A AU2017326013 A AU 2017326013A AU 2017326013 B2 AU2017326013 B2 AU 2017326013B2
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AU
Australia
Prior art keywords
pridopidine
bdnf
subject
rtt
symptom
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AU2017326013A
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AU2017326013A1 (en
Inventor
Michal Geva
Michael Hayden
Ralph Laufer
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Prilenia Neurotherapeutics Ltd
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Prilenia Neurotherapeutics Ltd
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Publication of AU2017326013A1 publication Critical patent/AU2017326013A1/en
Assigned to Prilenia Neurotherapeutics Ltd reassignment Prilenia Neurotherapeutics Ltd Amend patent request/document other than specification (104) Assignors: PRILENIA THERAPEUTICS DEVELOPMENT LTD.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
AU2017326013A 2016-09-16 2017-09-15 Use of pridopidine for treating Rett syndrome Active AU2017326013B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662395854P 2016-09-16 2016-09-16
US62/395,854 2016-09-16
PCT/US2017/051803 WO2018053280A1 (en) 2016-09-16 2017-09-15 Use of pridopidine for treating rett syndrome

Publications (2)

Publication Number Publication Date
AU2017326013A1 AU2017326013A1 (en) 2019-04-11
AU2017326013B2 true AU2017326013B2 (en) 2020-12-24

Family

ID=61619744

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017326013A Active AU2017326013B2 (en) 2016-09-16 2017-09-15 Use of pridopidine for treating Rett syndrome

Country Status (13)

Country Link
EP (2) EP4005570B1 (enExample)
JP (1) JP6977029B2 (enExample)
CN (1) CN109982686A (enExample)
AU (1) AU2017326013B2 (enExample)
BR (1) BR112019005040A2 (enExample)
CA (1) CA3036984C (enExample)
DK (2) DK4005570T3 (enExample)
ES (2) ES2909557T3 (enExample)
HU (1) HUE058314T2 (enExample)
IL (1) IL265342B2 (enExample)
MX (1) MX388845B (enExample)
PL (2) PL3512506T3 (enExample)
WO (1) WO2018053280A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
CA2913781C (en) 2013-06-21 2022-05-10 Teva Pharmaceutical Industries Ltd. Use of pridopidine for treating huntington's disease
CN110012661A (zh) 2016-08-24 2019-07-12 普瑞尼亚医疗发展有限公司 普利多匹定用于治疗肌张力障碍的用途
IL311081A (en) 2016-08-24 2024-04-01 Prilenia Neurotherapeutics Ltd Use of pyridofidine to treat functional decline
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
ES2909557T3 (es) 2016-09-16 2022-05-09 Prilenia Neurotherapeutics Ltd Utilización de la pridopidina para el tratamiento del síndrome de Rett
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
JP2022524927A (ja) 2019-02-02 2022-05-11 ステモニックス インコーポレイティド 創薬のためのヒトスフェロイドの使用方法
JP7585561B2 (ja) 2019-02-04 2024-11-19 プリレニア ニューロセラピューティクス リミテッド パーキンソン病およびパーキンソニズムに関連する他の疾患のための低用量プリドピジン
AU2020243692B2 (en) 2019-03-15 2023-03-02 Prilenia Neurotherapeutics Ltd. Treatment of mitochondrial associated diseases and disorders, including symptoms thereof using pridopidine
CN116472043A (zh) * 2020-10-20 2023-07-21 普瑞尼亚神经治疗有限公司 普利多匹定和类似物用于治疗焦虑和抑郁的用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015112601A1 (en) * 2014-01-22 2015-07-30 IVAX International GmbH Modified release formulations of pridopidine
US20160243098A1 (en) * 2015-02-25 2016-08-25 Teva Pharmaceuticals International Gmbh Use of pridopidine to improve cognitive function and for treating alzheimer's disease
WO2016138135A1 (en) * 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
ES2659577T3 (es) 2004-10-13 2018-03-16 Teva Pharmaceuticals International Gmbh Proceso para la síntesis de 4-(3-metanosulfonilfenil)-1-N-propil-piperidina
NZ608120A (en) 2010-09-03 2014-12-24 Ivax Int Gmbh Deuterated analogs of pridopidine useful as dopaminergic stabilizers
EP2787997A4 (en) * 2011-12-08 2015-05-27 Ivax Int Gmbh HYDROBROMIDE SALT OF PRIDOPIDINE
BR112014024672A8 (pt) 2012-04-04 2018-04-03 Ivax Int Gmbh Composições farmacêuticas para terapia de combinação
CA2913781C (en) 2013-06-21 2022-05-10 Teva Pharmaceutical Industries Ltd. Use of pridopidine for treating huntington's disease
ES2909557T3 (es) 2016-09-16 2022-05-09 Prilenia Neurotherapeutics Ltd Utilización de la pridopidina para el tratamiento del síndrome de Rett

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015112601A1 (en) * 2014-01-22 2015-07-30 IVAX International GmbH Modified release formulations of pridopidine
US20160243098A1 (en) * 2015-02-25 2016-08-25 Teva Pharmaceuticals International Gmbh Use of pridopidine to improve cognitive function and for treating alzheimer's disease
WO2016138135A1 (en) * 2015-02-25 2016-09-01 Teva Pharmaceuticals International Gmbh Sigma-1 receptor modulators for treating huntington's disease

Also Published As

Publication number Publication date
MX2019003069A (es) 2019-09-02
PL3512506T3 (pl) 2022-05-30
EP4005570A1 (en) 2022-06-01
DK3512506T3 (da) 2022-04-19
CN109982686A (zh) 2019-07-05
MX388845B (es) 2025-03-20
BR112019005040A2 (pt) 2019-07-16
EP3512506A1 (en) 2019-07-24
JP6977029B2 (ja) 2021-12-08
DK4005570T3 (da) 2024-08-19
EP4005570B1 (en) 2024-05-15
EP3512506B1 (en) 2022-01-26
HUE058314T2 (hu) 2022-07-28
AU2017326013A1 (en) 2019-04-11
ES2986807T3 (es) 2024-11-12
CA3036984A1 (en) 2018-03-22
IL265342A (en) 2019-05-30
EP3512506A4 (en) 2020-05-27
WO2018053280A1 (en) 2018-03-22
PL4005570T3 (pl) 2024-09-23
JP2019532926A (ja) 2019-11-14
CA3036984C (en) 2023-07-18
IL265342B2 (en) 2023-06-01
ES2909557T3 (es) 2022-05-09

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HB Alteration of name in register

Owner name: PRILENIA NEUROTHERAPEUTICS LTD

Free format text: FORMER NAME(S): PRILENIA THERAPEUTICS DEVELOPMENT LTD.

FGA Letters patent sealed or granted (standard patent)