JP6976943B2 - 抗補体因子Ｃ１ｑ Ｆａｂ断片及びその使用 - Google Patents

抗補体因子Ｃ１ｑ Ｆａｂ断片及びその使用 Download PDF

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JP6976943B2
JP6976943B2 JP2018526675A JP2018526675A JP6976943B2 JP 6976943 B2 JP6976943 B2 JP 6976943B2 JP 2018526675 A JP2018526675 A JP 2018526675A JP 2018526675 A JP2018526675 A JP 2018526675A JP 6976943 B2 JP6976943 B2 JP 6976943B2
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disease
antibody
fab fragment
antibody fab
complement
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JP2019501132A (ja
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イエドノック，テッド
サンカラナラヤナン，セテュ
ローセンタール，アーノン
レヴィテン，マイケル
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アネクソン，インコーポレーテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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JP2018526675A 2015-11-24 2016-11-23 抗補体因子Ｃ１ｑ Ｆａｂ断片及びその使用 Active JP6976943B2 (ja)

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US201562259227P 2015-11-24 2015-11-24
US62/259,227 2015-11-24
PCT/US2016/063587 WO2017091719A1 (en) 2015-11-24 2016-11-23 Anti-complement factor c1q fab fragments and uses thereof

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JP2019501132A JP2019501132A (ja) 2019-01-17
JP2019501132A5 JP2019501132A5 (enExample) 2020-01-09
JP6976943B2 true JP6976943B2 (ja) 2021-12-08

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US (3) US10723788B2 (enExample)
EP (1) EP3380518A4 (enExample)
JP (1) JP6976943B2 (enExample)
KR (1) KR102877741B1 (enExample)
CN (2) CN115260310B (enExample)
AU (1) AU2016361517C1 (enExample)
BR (1) BR112018010360A2 (enExample)
CA (1) CA3006092A1 (enExample)
IL (2) IL296130A (enExample)
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BR112018010360A2 (en) 2015-11-24 2018-12-04 Annexon, Inc. anti-c1q complement factor fab fragments and uses thereof
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BR112021021689A2 (pt) 2019-05-15 2022-03-22 Chugai Pharmaceutical Co Ltd Molécula de ligação a antígeno, composição farmacêutica, e método
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CN110716038B (zh) * 2019-10-23 2022-08-30 俞梦越 一种急性冠脉综合征补体检测试剂盒及其使用方法
CA3177879A1 (en) * 2020-05-05 2021-12-02 Jeanne T. PAZ Compositions and methods for treating epilepsy
CN112194719A (zh) * 2020-09-01 2021-01-08 中日友好医院(中日友好临床医学研究所) Crt抗原和mage-a1抗原的制备及其应用
CN112837822B (zh) * 2020-09-24 2023-05-02 广州市疾病预防控制中心(广州市卫生检验中心、广州市食品安全风险监测与评估中心、广州医科大学公共卫生研究院) 预测covid-19患者发生轻至重度进展的标志物及试剂盒和建立方法
AU2021361067A1 (en) * 2020-10-16 2023-06-01 Annexon, Inc. Compositions and methods for treating blood disorders
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US12486322B2 (en) * 2021-12-13 2025-12-02 Annexon, Inc. Anti-complement factor C1q antibodies with single binding arms and uses thereof
WO2023130001A1 (en) * 2021-12-30 2023-07-06 Annexon, Inc. Compositions and methods for treating huntington's disease
EP4518896A1 (en) * 2022-04-29 2025-03-12 Annexon, Inc. Compositions and methods for treating ocular diseases
CA3253133A1 (en) * 2022-05-13 2023-11-16 Annexon Inc COMPOSITIONS AND METHODS OF TREATMENT OF LUPUS NEPHRITIS
CN119371528B (zh) * 2024-10-30 2025-06-24 泰州市人民医院 一种C1q抗体及其应用、一种抑制补体经典途径活化的药剂及其应用

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