JP6956098B2 - 変異体ｐ５３機能を復元させるための方法および化合物 - Google Patents

変異体ｐ５３機能を復元させるための方法および化合物 Download PDF

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JP6956098B2
JP6956098B2 JP2018544186A JP2018544186A JP6956098B2 JP 6956098 B2 JP6956098 B2 JP 6956098B2 JP 2018544186 A JP2018544186 A JP 2018544186A JP 2018544186 A JP2018544186 A JP 2018544186A JP 6956098 B2 JP6956098 B2 JP 6956098B2
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indole
methyl
amino
propa
ethyl
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JP2019512465A5 (OSRAM
JP2019512465A (ja
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ビン ヴー，
ビン ヴー，
ロムヤー ドミニク，
ロムヤー ドミニク，
ホンジュ リ，
ホンジュ リ，
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ピーエムブイ ファーマシューティカルズ， インコーポレイテッド
ピーエムブイ ファーマシューティカルズ， インコーポレイテッド
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • G01N2333/4701—Details
    • G01N2333/4748—Details p53

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2018544186A 2016-02-19 2017-02-17 変異体ｐ５３機能を復元させるための方法および化合物 Active JP6956098B2 (ja)

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US201662297450P 2016-02-19 2016-02-19
US62/297,450 2016-02-19
PCT/US2017/018511 WO2017143291A1 (en) 2016-02-19 2017-02-17 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION

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CA3010847A1 (en) 2017-08-24
AU2017221472A1 (en) 2018-07-26
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IL286839A (en) 2021-10-31
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