JP6929645B2 - マルチトレース定量化 - Google Patents

マルチトレース定量化 Download PDF

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JP6929645B2
JP6929645B2 JP2016565003A JP2016565003A JP6929645B2 JP 6929645 B2 JP6929645 B2 JP 6929645B2 JP 2016565003 A JP2016565003 A JP 2016565003A JP 2016565003 A JP2016565003 A JP 2016565003A JP 6929645 B2 JP6929645 B2 JP 6929645B2
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xic
xic peak
correlated
peak profile
peak
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JP2017514140A5 (enExample
JP2017514140A (ja
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ゴルダナ イボセフ，
ゴルダナ イボセフ，
Original Assignee
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8634—Peak quality criteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8637—Peak shape
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2016565003A 2014-04-28 2015-04-14 マルチトレース定量化 Expired - Fee Related JP6929645B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461985335P 2014-04-28 2014-04-28
US61/985,335 2014-04-28
PCT/IB2015/000477 WO2015166322A1 (en) 2014-04-28 2015-04-14 Multi-trace quantitation

Publications (3)

Publication Number Publication Date
JP2017514140A JP2017514140A (ja) 2017-06-01
JP2017514140A5 JP2017514140A5 (enExample) 2018-03-22
JP6929645B2 true JP6929645B2 (ja) 2021-09-01

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JP2016565003A Expired - Fee Related JP6929645B2 (ja) 2014-04-28 2015-04-14 マルチトレース定量化

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US (1) US10732156B2 (enExample)
EP (1) EP3137891B1 (enExample)
JP (1) JP6929645B2 (enExample)
CN (1) CN106233138B (enExample)
CA (1) CA2947239A1 (enExample)
WO (1) WO2015166322A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020250158A1 (en) * 2019-06-12 2020-12-17 Dh Technologies Development Pte. Ltd. Peak integration correction without parameter adjustment
US20230366863A1 (en) * 2020-10-06 2023-11-16 Dh Technologies Development Pte. Ltd. Automated Modeling of LC Peak Shape
JP7605073B2 (ja) * 2021-09-27 2024-12-24 株式会社島津製作所 データ処理方法及びデータ処理システム

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JPS6285850A (ja) * 1985-10-11 1987-04-20 Shimadzu Corp エネルギ−スペクトルの成分ピ−ク分離方法
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JP3807306B2 (ja) * 1999-09-27 2006-08-09 株式会社日立製作所 クロマトデータ処理装置、クロマトデータ処理方法、及びクロマトグラフ分析装置
US7105806B2 (en) * 2003-11-26 2006-09-12 Applera Corporation Method and apparatus for de-convoluting a convoluted spectrum
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CN1712955A (zh) * 2004-06-25 2005-12-28 中国科学院大连化学物理研究所 一种精确测定色谱峰形参数和重叠峰面积的方法
WO2006011351A1 (en) * 2004-07-29 2006-02-02 Eisai R&D Management Co., Ltd. Absolute quantitation of protein contents based on exponentially modified protein abundance index by mass spectrometry
US20060255258A1 (en) * 2005-04-11 2006-11-16 Yongdong Wang Chromatographic and mass spectral date analysis
JP4577266B2 (ja) * 2006-05-16 2010-11-10 株式会社島津製作所 クロマトグラフ質量分析装置
US7983852B2 (en) * 2008-10-21 2011-07-19 Thermo Finnigan Llc Methods of automated spectral peak detection and quantification without user input
GB0915474D0 (en) 2009-09-04 2009-10-07 Micromass Ltd Multiple reaction monitoring with a time-of-flight based mass spectrometer
WO2011041656A2 (en) * 2009-10-02 2011-04-07 Metabolon Inc. Apparatus and associated method for analyzing small molecule components in a complex mixture
GB201002447D0 (en) * 2010-02-12 2010-03-31 Micromass Ltd Mass spectrometer
GB201002445D0 (en) 2010-02-12 2010-03-31 Micromass Ltd Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
RU2562607C2 (ru) * 2010-06-25 2015-09-10 ДжейЭкс НИППОН ОЙЛ ЭНД ЭНЕРДЖИ КОРПОРЕЙШН Катализатор гидродесульфуризации для жидкого нефтепродукта, способ его получения и способ гидроочистки
JP5370312B2 (ja) * 2010-08-23 2013-12-18 株式会社島津製作所 質量分析装置
WO2012032394A2 (en) * 2010-09-08 2012-03-15 Dh Technologies Development Pte. Ltd. Systems and methods for using variable mass selection window widths in tandem mass spectrometry
US8935101B2 (en) * 2010-12-16 2015-01-13 Thermo Finnigan Llc Method and apparatus for correlating precursor and product ions in all-ions fragmentation experiments
JP5454462B2 (ja) * 2010-12-22 2014-03-26 株式会社島津製作所 クロマトグラフ質量分析装置
JP5454484B2 (ja) * 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
JP5736235B2 (ja) 2011-05-23 2015-06-17 株式会社日立製作所 質量分析システム及びコンピュータプログラム
EP2807669A2 (en) * 2012-01-24 2014-12-03 Thermo Finnigan LLC Multinotch isolation for ms3 mass analysis
WO2013134771A1 (en) * 2012-03-09 2013-09-12 Torion Technologies, Inc. Deconvolution and identification algorithms for use on spectroscopic data
WO2013188879A1 (en) * 2012-06-16 2013-12-19 Atherotech, Inc. Measurement of serum lipoproteins
US9429549B2 (en) * 2012-09-28 2016-08-30 Shimadzu Corporation Chromatograph mass spectrometer
JP6132067B2 (ja) * 2014-03-03 2017-05-24 株式会社島津製作所 クロマトグラフ質量分析装置用データ処理装置及びプログラム

Also Published As

Publication number Publication date
CA2947239A1 (en) 2015-11-05
US20170038351A1 (en) 2017-02-09
WO2015166322A1 (en) 2015-11-05
EP3137891A4 (en) 2017-10-25
EP3137891B1 (en) 2024-01-17
JP2017514140A (ja) 2017-06-01
EP3137891A1 (en) 2017-03-08
CN106233138A (zh) 2016-12-14
CN106233138B (zh) 2019-03-01
US10732156B2 (en) 2020-08-04

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