JP6929645B2 - マルチトレース定量化 - Google Patents

マルチトレース定量化 Download PDF

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JP6929645B2
JP6929645B2 JP2016565003A JP2016565003A JP6929645B2 JP 6929645 B2 JP6929645 B2 JP 6929645B2 JP 2016565003 A JP2016565003 A JP 2016565003A JP 2016565003 A JP2016565003 A JP 2016565003A JP 6929645 B2 JP6929645 B2 JP 6929645B2
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xic
xic peak
correlated
peak profile
peak
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JP2017514140A (ja
JP2017514140A5 (enExample
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ゴルダナ イボセフ，
ゴルダナ イボセフ，
Original Assignee
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8634—Peak quality criteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8637—Peak shape
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

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  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Quality & Reliability (AREA)
  • Engineering & Computer Science (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2016565003A 2014-04-28 2015-04-14 マルチトレース定量化 Expired - Fee Related JP6929645B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461985335P 2014-04-28 2014-04-28
US61/985,335 2014-04-28
PCT/IB2015/000477 WO2015166322A1 (en) 2014-04-28 2015-04-14 Multi-trace quantitation

Publications (3)

Publication Number Publication Date
JP2017514140A JP2017514140A (ja) 2017-06-01
JP2017514140A5 JP2017514140A5 (enExample) 2018-03-22
JP6929645B2 true JP6929645B2 (ja) 2021-09-01

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JP2016565003A Expired - Fee Related JP6929645B2 (ja) 2014-04-28 2015-04-14 マルチトレース定量化

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US (1) US10732156B2 (enExample)
EP (1) EP3137891B1 (enExample)
JP (1) JP6929645B2 (enExample)
CN (1) CN106233138B (enExample)
CA (1) CA2947239A1 (enExample)
WO (1) WO2015166322A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7624400B2 (ja) * 2019-06-12 2025-01-30 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド パラメータ調節を伴わないピーク積分補正
CN115699247A (zh) * 2020-05-22 2023-02-03 Dh科技发展私人贸易有限公司 用于增加通量的方法
EP4226152B1 (en) * 2020-10-06 2025-12-03 DH Technologies Development Pte. Ltd. Automated modeling of lc peak shape
JP7605073B2 (ja) * 2021-09-27 2024-12-24 株式会社島津製作所 データ処理方法及びデータ処理システム
WO2026058168A1 (en) 2024-09-11 2026-03-19 Dh Technologies Development Pte. Ltd. Ms2-driven deconvolution of ms1 peaks that are co-eluting and isobaric, for improved accuracy and quantitation of compounds

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JP3807306B2 (ja) * 1999-09-27 2006-08-09 株式会社日立製作所 クロマトデータ処理装置、クロマトデータ処理方法、及びクロマトグラフ分析装置
US7105806B2 (en) * 2003-11-26 2006-09-12 Applera Corporation Method and apparatus for de-convoluting a convoluted spectrum
GB2412487A (en) * 2004-03-26 2005-09-28 Thermo Finnigan Llc A method of improving a mass spectrum
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JP4783743B2 (ja) 2004-07-29 2011-09-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 質量分析法による指数関数的に変換されたタンパク質発現量指標に基づくタンパク質含有量の絶対定量
US20060255258A1 (en) * 2005-04-11 2006-11-16 Yongdong Wang Chromatographic and mass spectral date analysis
JP4577266B2 (ja) * 2006-05-16 2010-11-10 株式会社島津製作所 クロマトグラフ質量分析装置
US7983852B2 (en) * 2008-10-21 2011-07-19 Thermo Finnigan Llc Methods of automated spectral peak detection and quantification without user input
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GB201002445D0 (en) 2010-02-12 2010-03-31 Micromass Ltd Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
CN103079697B (zh) * 2010-06-25 2015-07-01 吉坤日矿日石能源株式会社 烃油用加氢脱硫催化剂、其生产方法及烃油用加氢精制方法
JP5370312B2 (ja) 2010-08-23 2013-12-18 株式会社島津製作所 質量分析装置
EP2614517B1 (en) * 2010-09-08 2020-08-05 DH Technologies Development Pte. Ltd. Systems and methods for using variable mass selection window widths in tandem mass spectrometry
US8935101B2 (en) * 2010-12-16 2015-01-13 Thermo Finnigan Llc Method and apparatus for correlating precursor and product ions in all-ions fragmentation experiments
JP5454462B2 (ja) * 2010-12-22 2014-03-26 株式会社島津製作所 クロマトグラフ質量分析装置
JP5454484B2 (ja) 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
JP5736235B2 (ja) 2011-05-23 2015-06-17 株式会社日立製作所 質量分析システム及びコンピュータプログラム
EP2807669A2 (en) * 2012-01-24 2014-12-03 Thermo Finnigan LLC Multinotch isolation for ms3 mass analysis
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Also Published As

Publication number Publication date
WO2015166322A1 (en) 2015-11-05
EP3137891B1 (en) 2024-01-17
EP3137891A1 (en) 2017-03-08
JP2017514140A (ja) 2017-06-01
CN106233138B (zh) 2019-03-01
US20170038351A1 (en) 2017-02-09
CN106233138A (zh) 2016-12-14
EP3137891A4 (en) 2017-10-25
US10732156B2 (en) 2020-08-04
CA2947239A1 (en) 2015-11-05

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