GB201002445D0 - Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions - Google Patents

Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions

Info

Publication number
GB201002445D0
GB201002445D0 GBGB1002445.3A GB201002445A GB201002445D0 GB 201002445 D0 GB201002445 D0 GB 201002445D0 GB 201002445 A GB201002445 A GB 201002445A GB 201002445 D0 GB201002445 D0 GB 201002445D0
Authority
GB
United Kingdom
Prior art keywords
conformations
ionic
determination
ion mobility
exchange reactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1002445.3A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority to GBGB1002445.3A priority Critical patent/GB201002445D0/en
Publication of GB201002445D0 publication Critical patent/GB201002445D0/en
Priority to JP2012552478A priority patent/JP5718367B2/en
Priority to GB1102530.1A priority patent/GB2478044B/en
Priority to CA2789214A priority patent/CA2789214A1/en
Priority to PCT/GB2011/050273 priority patent/WO2011098833A2/en
Priority to US13/578,397 priority patent/US8981286B2/en
Priority to EP11704309.1A priority patent/EP2534669B1/en
Ceased legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0077—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction specific reactions other than fragmentation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
GBGB1002445.3A 2010-02-12 2010-02-12 Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions Ceased GB201002445D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GBGB1002445.3A GB201002445D0 (en) 2010-02-12 2010-02-12 Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
JP2012552478A JP5718367B2 (en) 2010-02-12 2011-02-14 Mass spectrometer with built-in hydrogen-deuterium exchange
GB1102530.1A GB2478044B (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange
CA2789214A CA2789214A1 (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange
PCT/GB2011/050273 WO2011098833A2 (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange
US13/578,397 US8981286B2 (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange
EP11704309.1A EP2534669B1 (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1002445.3A GB201002445D0 (en) 2010-02-12 2010-02-12 Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions

Publications (1)

Publication Number Publication Date
GB201002445D0 true GB201002445D0 (en) 2010-03-31

Family

ID=42110664

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1002445.3A Ceased GB201002445D0 (en) 2010-02-12 2010-02-12 Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
GB1102530.1A Active GB2478044B (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1102530.1A Active GB2478044B (en) 2010-02-12 2011-02-14 Mass spectrometer incorporating hydrogen-deuterium exchange

Country Status (6)

Country Link
US (1) US8981286B2 (en)
EP (1) EP2534669B1 (en)
JP (1) JP5718367B2 (en)
CA (1) CA2789214A1 (en)
GB (2) GB201002445D0 (en)
WO (1) WO2011098833A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2758917C (en) * 2009-04-14 2017-08-29 Northeastern University Rapid gas-phase isotopic labeling for enhanced detection of protein conformations
GB201019337D0 (en) * 2010-11-16 2010-12-29 Micromass Ltd Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis
KR101585323B1 (en) 2013-06-10 2016-01-14 경북대학교 산학협력단 A method for analysis of nitrogen-containing compounds in a mixture by using hydrogen/deuterium exchange and mass spectrometry
EP3137891B1 (en) 2014-04-28 2024-01-17 DH Technologies Development Pte. Ltd. Multi-trace quantitation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1002445A (en) 1960-08-29 1965-08-25 Sol Bernard Radlove Improved emulsifier
US6822224B2 (en) 2000-03-14 2004-11-23 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (FAIMS)tandem mass spectrometry
US6570155B1 (en) * 2000-04-11 2003-05-27 Applied Materials, Inc. Bi-directional electron beam scanning apparatus
US7586088B2 (en) * 2001-06-21 2009-09-08 Micromass Uk Limited Mass spectrometer and method of mass spectrometry
GB0305796D0 (en) * 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US7457708B2 (en) * 2003-03-13 2008-11-25 Agilent Technologies Inc Methods and devices for identifying related ions from chromatographic mass spectral datasets containing overlapping components
JP2006522340A (en) * 2003-04-02 2006-09-28 メルク　エンド　カムパニー　インコーポレーテッド Analyzing mass spectrometry data
US6983213B2 (en) * 2003-10-20 2006-01-03 Cerno Bioscience Llc Methods for operating mass spectrometry (MS) instrument systems
EP1636822A2 (en) * 2003-05-15 2006-03-22 Electrophoretics Limited Mass spectrometry
US20050255606A1 (en) * 2004-05-13 2005-11-17 Biospect, Inc., A California Corporation Methods for accurate component intensity extraction from separations-mass spectrometry data
CA2609802A1 (en) * 2005-05-27 2006-12-07 Ionwerks, Inc. Multi-beam ion mobility time-of-flight mass spectrometer with bipolar ion extraction and zwitterion detection
US7838822B2 (en) * 2007-11-09 2010-11-23 Dh Technologies Development Pte. Ltd. Linear FAIMS power supply
US8666681B2 (en) * 2008-06-04 2014-03-04 Shimadzu Corporation Mass analysis data analyzing method and mass analysis data analyzing apparatus
GB0820308D0 (en) * 2008-11-06 2008-12-17 Micromass Ltd Mass spectrometer
CA2758917C (en) * 2009-04-14 2017-08-29 Northeastern University Rapid gas-phase isotopic labeling for enhanced detection of protein conformations

Also Published As

Publication number Publication date
EP2534669B1 (en) 2020-04-01
GB201102530D0 (en) 2011-03-30
WO2011098833A2 (en) 2011-08-18
GB2478044B (en) 2014-12-31
US8981286B2 (en) 2015-03-17
CA2789214A1 (en) 2011-08-18
JP2013519974A (en) 2013-05-30
WO2011098833A3 (en) 2011-10-06
US20130206974A1 (en) 2013-08-15
GB2478044A (en) 2011-08-24
EP2534669A2 (en) 2012-12-19
JP5718367B2 (en) 2015-05-13

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)