CA2947239A1 - Multi-trace quantitation - Google Patents

Multi-trace quantitation Download PDF

Info

Publication number
CA2947239A1
CA2947239A1 CA2947239A CA2947239A CA2947239A1 CA 2947239 A1 CA2947239 A1 CA 2947239A1 CA 2947239 A CA2947239 A CA 2947239A CA 2947239 A CA2947239 A CA 2947239A CA 2947239 A1 CA2947239 A1 CA 2947239A1
Authority
CA
Canada
Prior art keywords
peak
correlated
profiles
peak profile
profile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2947239A
Other languages
English (en)
French (fr)
Inventor
Gordana Ivosev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DH Technologies Development Pte Ltd
Original Assignee
DH Technologies Development Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DH Technologies Development Pte Ltd filed Critical DH Technologies Development Pte Ltd
Publication of CA2947239A1 publication Critical patent/CA2947239A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8634—Peak quality criteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8631—Peaks
    • G01N30/8637—Peak shape
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CA2947239A 2014-04-28 2015-04-14 Multi-trace quantitation Abandoned CA2947239A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461985335P 2014-04-28 2014-04-28
US61/985,335 2014-04-28
PCT/IB2015/000477 WO2015166322A1 (en) 2014-04-28 2015-04-14 Multi-trace quantitation

Publications (1)

Publication Number Publication Date
CA2947239A1 true CA2947239A1 (en) 2015-11-05

Family

ID=54358228

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2947239A Abandoned CA2947239A1 (en) 2014-04-28 2015-04-14 Multi-trace quantitation

Country Status (6)

Country Link
US (1) US10732156B2 (enExample)
EP (1) EP3137891B1 (enExample)
JP (1) JP6929645B2 (enExample)
CN (1) CN106233138B (enExample)
CA (1) CA2947239A1 (enExample)
WO (1) WO2015166322A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020250158A1 (en) * 2019-06-12 2020-12-17 Dh Technologies Development Pte. Ltd. Peak integration correction without parameter adjustment
EP4226152B1 (en) * 2020-10-06 2025-12-03 DH Technologies Development Pte. Ltd. Automated modeling of lc peak shape
JP7605073B2 (ja) * 2021-09-27 2024-12-24 株式会社島津製作所 データ処理方法及びデータ処理システム

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353242A (en) * 1980-12-16 1982-10-12 University Of Utah Research Foundation Multichannel detection and resolution of chromatographic peaks
JPS6285850A (ja) * 1985-10-11 1987-04-20 Shimadzu Corp エネルギ−スペクトルの成分ピ−ク分離方法
US5938932A (en) * 1997-11-14 1999-08-17 Pharmacopeia, Inc. High-throughput method and apparatus for identifying, quantitating and determining the purity of chemical compounds in mixtures
WO2001023880A1 (en) * 1999-09-27 2001-04-05 Hitachi, Ltd. Method and apparatus for chromatographic data processing, and chromatograph
US7105806B2 (en) * 2003-11-26 2006-09-12 Applera Corporation Method and apparatus for de-convoluting a convoluted spectrum
GB2412487A (en) * 2004-03-26 2005-09-28 Thermo Finnigan Llc A method of improving a mass spectrum
US7117103B2 (en) 2004-06-03 2006-10-03 Agilent Technologies, Inc. Rapid automatic target compound confirmation using deconvolution and spectral matching
CN1712955A (zh) * 2004-06-25 2005-12-28 中国科学院大连化学物理研究所 一种精确测定色谱峰形参数和重叠峰面积的方法
EP1787125A4 (en) * 2004-07-29 2008-10-29 Eisai R&D Man Co Ltd ABSOLUTE QUANTIFICATION OF PROTEIN CONTENT BASED ON ABUNDANCE INDEX OF EXPONENTIALLY MODIFIED PROTEINS BY MASS SPECTROMETRY
US20060255258A1 (en) * 2005-04-11 2006-11-16 Yongdong Wang Chromatographic and mass spectral date analysis
JP4577266B2 (ja) * 2006-05-16 2010-11-10 株式会社島津製作所 クロマトグラフ質量分析装置
US7983852B2 (en) * 2008-10-21 2011-07-19 Thermo Finnigan Llc Methods of automated spectral peak detection and quantification without user input
GB0915474D0 (en) 2009-09-04 2009-10-07 Micromass Ltd Multiple reaction monitoring with a time-of-flight based mass spectrometer
CN102667789A (zh) * 2009-10-02 2012-09-12 梅塔博隆有限公司 用于分析复杂混合物中小分子成分的设备和相关方法
GB201002445D0 (en) 2010-02-12 2010-03-31 Micromass Ltd Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
GB201002447D0 (en) 2010-02-12 2010-03-31 Micromass Ltd Mass spectrometer
WO2011162228A1 (ja) * 2010-06-25 2011-12-29 Ｊｘ日鉱日石エネルギー株式会社 炭化水素油の水素化脱硫触媒及びその製造方法並びに炭化水素油の水素化精製方法
JP5370312B2 (ja) * 2010-08-23 2013-12-18 株式会社島津製作所 質量分析装置
US8809772B2 (en) * 2010-09-08 2014-08-19 Dh Technologies Development Pte. Ltd. Systems and methods for using variable mass selection window widths in tandem mass spectrometry
US8935101B2 (en) * 2010-12-16 2015-01-13 Thermo Finnigan Llc Method and apparatus for correlating precursor and product ions in all-ions fragmentation experiments
JP5454462B2 (ja) * 2010-12-22 2014-03-26 株式会社島津製作所 クロマトグラフ質量分析装置
JP5454484B2 (ja) * 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
JP5736235B2 (ja) 2011-05-23 2015-06-17 株式会社日立製作所 質量分析システム及びコンピュータプログラム
WO2013112677A2 (en) * 2012-01-24 2013-08-01 Thermo Finnigan Llc Multinotch isolation for ms3 mass analysis
US9640374B2 (en) * 2012-03-09 2017-05-02 Torion Technologies, Inc. Deconvolution and identification algorithms for use on spectroscopic data
WO2013188879A1 (en) * 2012-06-16 2013-12-19 Atherotech, Inc. Measurement of serum lipoproteins
JP5858166B2 (ja) * 2012-09-28 2016-02-10 株式会社島津製作所 クロマトグラフ質量分析装置
JP6132067B2 (ja) * 2014-03-03 2017-05-24 株式会社島津製作所 クロマトグラフ質量分析装置用データ処理装置及びプログラム

Also Published As

Publication number Publication date
US10732156B2 (en) 2020-08-04
CN106233138A (zh) 2016-12-14
EP3137891A1 (en) 2017-03-08
WO2015166322A1 (en) 2015-11-05
JP2017514140A (ja) 2017-06-01
US20170038351A1 (en) 2017-02-09
EP3137891B1 (en) 2024-01-17
EP3137891A4 (en) 2017-10-25
JP6929645B2 (ja) 2021-09-01
CN106233138B (zh) 2019-03-01

Similar Documents

Publication Publication Date Title
EP2798664B1 (en) Use of windowed mass spectrometry data for retention time determination or confirmation
US9472387B2 (en) Systems and methods for identifying precursor ions from product ions using arbitrary transmission windowing
US11442047B2 (en) Chromatograph mass spectrometry data processing device and chromatograph mass spectrometry data processing program
JPWO2018109895A1 (ja) 質量分析装置
US9117638B2 (en) Intelligent background data acquisition and subtraction
US8560248B2 (en) Systems and methods for extending the dynamic range of mass spectrometry
US10732156B2 (en) Multi-trace quantitation
CN107209151B (zh) 干扰检测及所关注峰值解卷积
JP7624400B2 (ja) パラメータ調節を伴わないピーク積分補正
CA2967769A1 (en) Determining the identity of modified compounds
WO2016125060A1 (en) Detecting mass spectrometry based similarity via curve subtraction
US10236167B1 (en) Peak waveform processing device
EP2936545B1 (en) Interlacing to improve sampling of data when ramping parameters
US20250166981A1 (en) Data Processing Method, Computer Readable Medium, Information Processing Apparatus, and Gas Chromatograph Mass Spectrometer

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20211123

FZDE Discontinued

Effective date: 20211123