JP6923659B2 - 多能性抗炎症及び代謝調節剤を用いた炎症関連症状の治療方法 - Google Patents

多能性抗炎症及び代謝調節剤を用いた炎症関連症状の治療方法 Download PDF

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JP6923659B2
JP6923659B2 JP2019541901A JP2019541901A JP6923659B2 JP 6923659 B2 JP6923659 B2 JP 6923659B2 JP 2019541901 A JP2019541901 A JP 2019541901A JP 2019541901 A JP2019541901 A JP 2019541901A JP 6923659 B2 JP6923659 B2 JP 6923659B2
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inflammatory
pharmaceutically acceptable
pharmaceutical compositions
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JP2019531356A5 (enExample
JP2019531356A (ja
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バッチャーニ、カルロス
ロペス、グローリア
エスカンデ、カルロス
ドゥアルテ、ホルヘ ロドリゲス
ドゥアルテ、ホルヘ ロドリゲス
キンタ、ウィリアムズ ポルカル
キンタ、ウィリアムズ ポルカル
カプッチョ、ロジーナ ダプエト
カプッチョ、ロジーナ ダプエト
ロペス、ヘルマン ガリウッシ
ロペス、ヘルマン ガリウッシ
ヌニェス、マリア ガラット
ヌニェス、マリア ガラット
ヒル、マルセロ
セゴビア、メルセデス
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Universidad de la Republica
Institut Pasteur de Montevideo
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Universidad de la Republica
Institut Pasteur de Montevideo
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019541901A 2016-10-14 2017-10-16 多能性抗炎症及び代謝調節剤を用いた炎症関連症状の治療方法 Active JP6923659B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408459P 2016-10-14 2016-10-14
US62/408,459 2016-10-14
US201762570973P 2017-10-11 2017-10-11
US62/570,973 2017-10-11
PCT/IB2017/056417 WO2018069907A1 (en) 2016-10-14 2017-10-16 Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

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JP2019531356A JP2019531356A (ja) 2019-10-31
JP2019531356A5 JP2019531356A5 (enExample) 2020-11-12
JP6923659B2 true JP6923659B2 (ja) 2021-08-25

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JP2019541901A Active JP6923659B2 (ja) 2016-10-14 2017-10-16 多能性抗炎症及び代謝調節剤を用いた炎症関連症状の治療方法

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US (3) US10537537B2 (enExample)
EP (2) EP3525780B1 (enExample)
JP (1) JP6923659B2 (enExample)
CN (1) CN110325182B (enExample)
AU (1) AU2017342167B2 (enExample)
CL (1) CL2019001014A1 (enExample)
ES (2) ES2886122T3 (enExample)
MX (1) MX394475B (enExample)
WO (1) WO2018069907A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190080A1 (ar) 2016-10-14 2019-04-11 Bayer Pharma AG مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
AU2017444990B2 (en) * 2017-12-27 2022-12-01 Carlos Batthyány Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDs) and methods of treating inflammation related conditions
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) * 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Family Cites Families (12)

* Cited by examiner, † Cited by third party
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JPS5113140B2 (enExample) * 1972-01-13 1976-04-26
JPS5113140A (en) 1974-07-23 1976-02-02 Sankyo Alu Ind Kinzokuseitoshojino nakazan
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
WO2005037323A2 (en) * 2003-10-10 2005-04-28 University Of Louisville Research Foundation, Inc. Use of gro to treat or prevent inflammation
US20060247263A1 (en) * 2005-04-19 2006-11-02 Amgen Inc. Substituted heterocyclic compounds and methods of use
US8933255B2 (en) * 2008-12-31 2015-01-13 Nitromega Corp. Nutraceuticals containing nitro fatty acids
AU2013257717A1 (en) 2012-05-10 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of metabolic syndrome
WO2015073527A1 (en) 2013-11-12 2015-05-21 Complexa, Inc. Nitroalkene tocopherols and analogs thereof for use in the treatment and prevention of inflammation related conditions
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Also Published As

Publication number Publication date
EP3525780B1 (en) 2021-06-02
EP3525780A1 (en) 2019-08-21
AU2017342167B2 (en) 2023-01-12
CN110325182B (zh) 2023-05-23
CN110325182A (zh) 2019-10-11
EP3878456A1 (en) 2021-09-15
AU2017342167A1 (en) 2019-06-06
CL2019001014A1 (es) 2019-11-29
WO2018069907A1 (en) 2018-04-19
US10537537B2 (en) 2020-01-21
MX394475B (es) 2025-03-24
US12280029B2 (en) 2025-04-22
US20250352501A1 (en) 2025-11-20
US20220296546A1 (en) 2022-09-22
ES2886122T3 (es) 2021-12-16
MX2019004402A (es) 2019-09-26
US20180104202A1 (en) 2018-04-19
ES2945822T3 (es) 2023-07-07
JP2019531356A (ja) 2019-10-31
EP3878456B1 (en) 2023-03-15

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