AU2017342167B2 - Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators - Google Patents

Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators Download PDF

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Publication number
AU2017342167B2
AU2017342167B2 AU2017342167A AU2017342167A AU2017342167B2 AU 2017342167 B2 AU2017342167 B2 AU 2017342167B2 AU 2017342167 A AU2017342167 A AU 2017342167A AU 2017342167 A AU2017342167 A AU 2017342167A AU 2017342167 B2 AU2017342167 B2 AU 2017342167B2
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Australia
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subject
pharmaceutically acceptable
compound
inhibitor
effective amount
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AU2017342167A
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AU2017342167A1 (en
Inventor
Carlos Batthyány
Rosina DAPUETO CAPUCCIO
Carlos ESCANDE
Germán GALLIUSSI LÓPEZ
María GARAT NUÑEZ
Marcelo HILL
Gloria LÓPEZ
Williams PORCAL QUINTA
Jorge RODRIGUEZ DUARTE
Mercedes SEGOVIA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de la Republica
Institut Pasteur de Montevideo
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Universidad de la Republica
Institut Pasteur de Montevideo
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2017342167A 2016-10-14 2017-10-16 Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators Active AU2017342167B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408459P 2016-10-14 2016-10-14
US62/408,459 2016-10-14
US201762570973P 2017-10-11 2017-10-11
US62/570,973 2017-10-11
PCT/IB2017/056417 WO2018069907A1 (en) 2016-10-14 2017-10-16 Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Publications (2)

Publication Number Publication Date
AU2017342167A1 AU2017342167A1 (en) 2019-06-06
AU2017342167B2 true AU2017342167B2 (en) 2023-01-12

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Family Applications (1)

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AU2017342167A Active AU2017342167B2 (en) 2016-10-14 2017-10-16 Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Country Status (9)

Country Link
US (3) US10537537B2 (enExample)
EP (2) EP3525780B1 (enExample)
JP (1) JP6923659B2 (enExample)
CN (1) CN110325182B (enExample)
AU (1) AU2017342167B2 (enExample)
CL (1) CL2019001014A1 (enExample)
ES (2) ES2886122T3 (enExample)
MX (1) MX394475B (enExample)
WO (1) WO2018069907A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190080A1 (ar) 2016-10-14 2019-04-11 Bayer Pharma AG مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
AU2017444990B2 (en) * 2017-12-27 2022-12-01 Carlos Batthyány Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDs) and methods of treating inflammation related conditions
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) * 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (enExample) * 1972-01-13 1973-05-22

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113140A (en) 1974-07-23 1976-02-02 Sankyo Alu Ind Kinzokuseitoshojino nakazan
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
WO2005037323A2 (en) * 2003-10-10 2005-04-28 University Of Louisville Research Foundation, Inc. Use of gro to treat or prevent inflammation
US20060247263A1 (en) * 2005-04-19 2006-11-02 Amgen Inc. Substituted heterocyclic compounds and methods of use
US8933255B2 (en) * 2008-12-31 2015-01-13 Nitromega Corp. Nutraceuticals containing nitro fatty acids
AU2013257717A1 (en) 2012-05-10 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of metabolic syndrome
WO2015073527A1 (en) 2013-11-12 2015-05-21 Complexa, Inc. Nitroalkene tocopherols and analogs thereof for use in the treatment and prevention of inflammation related conditions
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (enExample) * 1972-01-13 1973-05-22

Also Published As

Publication number Publication date
EP3525780B1 (en) 2021-06-02
EP3525780A1 (en) 2019-08-21
CN110325182B (zh) 2023-05-23
CN110325182A (zh) 2019-10-11
EP3878456A1 (en) 2021-09-15
AU2017342167A1 (en) 2019-06-06
CL2019001014A1 (es) 2019-11-29
WO2018069907A1 (en) 2018-04-19
US10537537B2 (en) 2020-01-21
MX394475B (es) 2025-03-24
US12280029B2 (en) 2025-04-22
US20250352501A1 (en) 2025-11-20
US20220296546A1 (en) 2022-09-22
JP6923659B2 (ja) 2021-08-25
ES2886122T3 (es) 2021-12-16
MX2019004402A (es) 2019-09-26
US20180104202A1 (en) 2018-04-19
ES2945822T3 (es) 2023-07-07
JP2019531356A (ja) 2019-10-31
EP3878456B1 (en) 2023-03-15

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Legal Events

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application
NA Applications received for extensions of time, section 223

Free format text: AN APPLICATION TO EXTEND THE TIME FROM 16 OCT 2021 TO 16 JUN 2022 IN WHICH TO PAY A CONTINUATION FEE HAS BEEN FILED

NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO PAY A CONTINUATION FEE HAS BEEN EXTENDED TO 16 JUN 2022

FGA Letters patent sealed or granted (standard patent)