CN110325182B - 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法 - Google Patents

使用多能抗炎和代谢调节剂治疗炎症相关病症的方法 Download PDF

Info

Publication number
CN110325182B
CN110325182B CN201780077323.2A CN201780077323A CN110325182B CN 110325182 B CN110325182 B CN 110325182B CN 201780077323 A CN201780077323 A CN 201780077323A CN 110325182 B CN110325182 B CN 110325182B
Authority
CN
China
Prior art keywords
sana
available
inflammatory
effective amount
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780077323.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN110325182A (zh
Inventor
卡洛斯·鲍贾尼
格洛里亚·洛佩斯
卡洛斯·埃斯康德
乔治·罗德里格斯·杜阿尔特
威廉姆斯·波卡尔·昆塔
罗西娜·达普托·卡普乔
格尔曼·加柳西·洛佩斯
玛丽亚·加拉特·努涅斯
马塞洛·希尔
梅塞德斯·塞戈维亚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de la Republica
Institut Pasteur de Montevideo
Original Assignee
Universidad de la Republica
Institut Pasteur de Montevideo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de la Republica, Institut Pasteur de Montevideo filed Critical Universidad de la Republica
Publication of CN110325182A publication Critical patent/CN110325182A/zh
Application granted granted Critical
Publication of CN110325182B publication Critical patent/CN110325182B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201780077323.2A 2016-10-14 2017-10-16 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法 Active CN110325182B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408459P 2016-10-14 2016-10-14
US62/408,459 2016-10-14
US201762570973P 2017-10-11 2017-10-11
US62/570,973 2017-10-11
PCT/IB2017/056417 WO2018069907A1 (en) 2016-10-14 2017-10-16 Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Publications (2)

Publication Number Publication Date
CN110325182A CN110325182A (zh) 2019-10-11
CN110325182B true CN110325182B (zh) 2023-05-23

Family

ID=60382484

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780077323.2A Active CN110325182B (zh) 2016-10-14 2017-10-16 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法

Country Status (9)

Country Link
US (3) US10537537B2 (enExample)
EP (2) EP3525780B1 (enExample)
JP (1) JP6923659B2 (enExample)
CN (1) CN110325182B (enExample)
AU (1) AU2017342167B2 (enExample)
CL (1) CL2019001014A1 (enExample)
ES (2) ES2886122T3 (enExample)
MX (1) MX394475B (enExample)
WO (1) WO2018069907A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190080A1 (ar) 2016-10-14 2019-04-11 Bayer Pharma AG مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
AU2017444990B2 (en) * 2017-12-27 2022-12-01 Carlos Batthyány Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDs) and methods of treating inflammation related conditions
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) * 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (enExample) * 1972-01-13 1973-05-22
WO2005037323A2 (en) * 2003-10-10 2005-04-28 University Of Louisville Research Foundation, Inc. Use of gro to treat or prevent inflammation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113140A (en) 1974-07-23 1976-02-02 Sankyo Alu Ind Kinzokuseitoshojino nakazan
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
US20060247263A1 (en) * 2005-04-19 2006-11-02 Amgen Inc. Substituted heterocyclic compounds and methods of use
US8933255B2 (en) * 2008-12-31 2015-01-13 Nitromega Corp. Nutraceuticals containing nitro fatty acids
AU2013257717A1 (en) 2012-05-10 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of metabolic syndrome
WO2015073527A1 (en) 2013-11-12 2015-05-21 Complexa, Inc. Nitroalkene tocopherols and analogs thereof for use in the treatment and prevention of inflammation related conditions
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
MX394475B (es) 2016-10-14 2025-03-24 Inst Pasteur De Montevideo Métodos para el tratamiento de las condiciones relacionadas con la inflamación utilizando moduladores antiinflamatorios y metábolicos pluripotentes.
WO2019145899A1 (en) * 2018-01-24 2019-08-01 Institut Pasteur De Montevideo Methods for treating heart transplant rejection
AU2019344692B2 (en) 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4834850A (enExample) * 1972-01-13 1973-05-22
WO2005037323A2 (en) * 2003-10-10 2005-04-28 University Of Louisville Research Foundation, Inc. Use of gro to treat or prevent inflammation

Also Published As

Publication number Publication date
EP3525780B1 (en) 2021-06-02
EP3525780A1 (en) 2019-08-21
AU2017342167B2 (en) 2023-01-12
CN110325182A (zh) 2019-10-11
EP3878456A1 (en) 2021-09-15
AU2017342167A1 (en) 2019-06-06
CL2019001014A1 (es) 2019-11-29
WO2018069907A1 (en) 2018-04-19
US10537537B2 (en) 2020-01-21
MX394475B (es) 2025-03-24
US12280029B2 (en) 2025-04-22
US20250352501A1 (en) 2025-11-20
US20220296546A1 (en) 2022-09-22
JP6923659B2 (ja) 2021-08-25
ES2886122T3 (es) 2021-12-16
MX2019004402A (es) 2019-09-26
US20180104202A1 (en) 2018-04-19
ES2945822T3 (es) 2023-07-07
JP2019531356A (ja) 2019-10-31
EP3878456B1 (en) 2023-03-15

Similar Documents

Publication Publication Date Title
CN110325182B (zh) 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法
US20250099411A1 (en) Methods of Treatment of Inflammation Related Conditions Using Pluripotent Anti-Inflammatory and Metabolic Modulators
JP2021183640A (ja) 活性化脂肪酸の治療有効量を使用する疾患の予防、処置および逆転
US11400066B2 (en) Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
US10906864B2 (en) Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDS) and methods of treating inflammation related conditions
US10632132B2 (en) Methods for treating heart transplant rejection
EP3732162B1 (en) Nitroalkene non steroidal anti-inflammatory drugs (na-nsaids) and methods of treating inflammation related conditions

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant