ES2945822T3 - Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación - Google Patents

Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación Download PDF

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Publication number
ES2945822T3
ES2945822T3 ES21170218T ES21170218T ES2945822T3 ES 2945822 T3 ES2945822 T3 ES 2945822T3 ES 21170218 T ES21170218 T ES 21170218T ES 21170218 T ES21170218 T ES 21170218T ES 2945822 T3 ES2945822 T3 ES 2945822T3
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ES
Spain
Prior art keywords
compound
sana
available
subject
effective amount
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES21170218T
Other languages
English (en)
Spanish (es)
Inventor
Carlos Batthyany
Gloria Lopez
Carlos Escande
Duarte Jorge Rodriguez
Quinta Williams Porcal
Capuccio Rosina Dapueto
Lopez Germán Galliussi
Nunez María Garat
Marcelo Hill
Mercedes Segovia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de la Republica
Institut Pasteur de Montevideo
Original Assignee
Universidad de la Republica
Institut Pasteur de Montevideo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of ES2945822T3 publication Critical patent/ES2945822T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES21170218T 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación Active ES2945822T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662408459P 2016-10-14 2016-10-14
US201762570973P 2017-10-11 2017-10-11

Publications (1)

Publication Number Publication Date
ES2945822T3 true ES2945822T3 (es) 2023-07-07

Family

ID=60382484

Family Applications (2)

Application Number Title Priority Date Filing Date
ES21170218T Active ES2945822T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación
ES17800605T Active ES2886122T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES17800605T Active ES2886122T3 (es) 2016-10-14 2017-10-16 Moduladores antinflamatorios y metabólicos pluripotentes para el tratamiento de afecciones relacionadas con la inflamación

Country Status (9)

Country Link
US (3) US10537537B2 (enExample)
EP (2) EP3525780B1 (enExample)
JP (1) JP6923659B2 (enExample)
CN (1) CN110325182B (enExample)
AU (1) AU2017342167B2 (enExample)
CL (1) CL2019001014A1 (enExample)
ES (2) ES2945822T3 (enExample)
MX (1) MX394475B (enExample)
WO (1) WO2018069907A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190080A1 (ar) 2016-10-14 2019-04-11 Bayer Pharma AG مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
CN110325182B (zh) 2016-10-14 2023-05-23 蒙得维的亚巴斯德研究所 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法
CN111655665B (zh) * 2017-12-27 2024-11-15 蒙得维的亚巴斯德研究所 硝基烯烃非甾体抗炎药(na-nsaids)及治疗炎症相关病症的方法
US10632132B2 (en) * 2018-01-24 2020-04-28 Carlos Batthyány Methods for treating heart transplant rejection
AU2019344692B2 (en) * 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
WO2025238423A2 (en) * 2024-05-14 2025-11-20 Institut Pasteur De Montevideo Methods of treating metabolic disorders and combination products for use in the same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113140B2 (enExample) * 1972-01-13 1976-04-26
JPS5113140A (en) 1974-07-23 1976-02-02 Sankyo Alu Ind Kinzokuseitoshojino nakazan
ES2136581B1 (es) * 1998-05-27 2000-09-16 Uriach & Cia Sa J Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb.
US20050187176A1 (en) * 2003-10-10 2005-08-25 Bates Paula J. Method for inhibiting NF-kappa B signaling and use to treat or prevent human diseases
US20060247263A1 (en) * 2005-04-19 2006-11-02 Amgen Inc. Substituted heterocyclic compounds and methods of use
AU2009334476B2 (en) * 2008-12-31 2013-08-29 Nitromega Corp. Nutraceuticals containing nitro fatty acids
SG11201407411SA (en) 2012-05-10 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of metabolic syndrome
WO2015073527A1 (en) 2013-11-12 2015-05-21 Complexa, Inc. Nitroalkene tocopherols and analogs thereof for use in the treatment and prevention of inflammation related conditions
US11400066B2 (en) 2016-10-14 2022-08-02 Institut Pasteur De Montevideo Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
CN110325182B (zh) 2016-10-14 2023-05-23 蒙得维的亚巴斯德研究所 使用多能抗炎和代谢调节剂治疗炎症相关病症的方法
US10632132B2 (en) * 2018-01-24 2020-04-28 Carlos Batthyány Methods for treating heart transplant rejection
AU2019344692B2 (en) 2018-09-20 2025-07-03 Carlos Batthyány Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators

Also Published As

Publication number Publication date
EP3525780B1 (en) 2021-06-02
US20220296546A1 (en) 2022-09-22
US20250352501A1 (en) 2025-11-20
US20180104202A1 (en) 2018-04-19
US10537537B2 (en) 2020-01-21
WO2018069907A1 (en) 2018-04-19
ES2886122T3 (es) 2021-12-16
CN110325182A (zh) 2019-10-11
US12280029B2 (en) 2025-04-22
CN110325182B (zh) 2023-05-23
EP3878456B1 (en) 2023-03-15
JP2019531356A (ja) 2019-10-31
CL2019001014A1 (es) 2019-11-29
AU2017342167A1 (en) 2019-06-06
MX2019004402A (es) 2019-09-26
EP3525780A1 (en) 2019-08-21
AU2017342167B2 (en) 2023-01-12
EP3878456A1 (en) 2021-09-15
MX394475B (es) 2025-03-24
JP6923659B2 (ja) 2021-08-25

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