JP6923543B2 - Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール - Google Patents

Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール Download PDF

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JP6923543B2
JP6923543B2 JP2018541636A JP2018541636A JP6923543B2 JP 6923543 B2 JP6923543 B2 JP 6923543B2 JP 2018541636 A JP2018541636 A JP 2018541636A JP 2018541636 A JP2018541636 A JP 2018541636A JP 6923543 B2 JP6923543 B2 JP 6923543B2
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triazole
methoxy
phenyl
pyrimidine
fluoro
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JP2019504854A (ja
JP2019504854A5 (enExample
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チェン，ガン
シー． クロヴィアン，クリスタ
シー． クロヴィアン，クリスタ
アール． コート，ヘザー
アール． コート，ヘザー
エー． ドゥヴォラク，カート
エー． ドゥヴォラク，カート
エフ． ゲリン，クリスティン
エフ． ゲリン，クリスティン
ヒスコックス，アフトン
エー． リタヴィック，マイケル
エー． リタヴィック，マイケル
シー． レック，ジェィソン
シー． レック，ジェィソン
ソヨデ−ジョンソン，アキノラ
ステン，ブライス
エル． ウォール，ジェシカ
エル． ウォール，ジェシカ
ジャン，ウェイ
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ヤンセン ファーマシューティカ エヌ．ベー．
ヤンセン ファーマシューティカ エヌ．ベー．
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
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  • General Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
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  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2018541636A 2016-02-10 2017-02-09 Ｎｒ２ｂ選択的ｎｍｄａ調節因子としての置換１，２，３−トリアゾール Expired - Fee Related JP6923543B2 (ja)

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Application Number Priority Date Filing Date Title
US201662293680P 2016-02-10 2016-02-10
US62/293,680 2016-02-10
PCT/US2017/017093 WO2017139428A1 (en) 2016-02-10 2017-02-09 Substituted 1,2,3-triazoles as nr2b-selective nmda modulators

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JP2019504854A JP2019504854A (ja) 2019-02-21
JP2019504854A5 JP2019504854A5 (enExample) 2020-03-26
JP6923543B2 true JP6923543B2 (ja) 2021-08-18

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US (3) US10071988B2 (enExample)
EP (1) EP3414233A1 (enExample)
JP (1) JP6923543B2 (enExample)
KR (1) KR20180108822A (enExample)
CN (1) CN109071488B (enExample)
AU (1) AU2017217542B2 (enExample)
BR (1) BR112018016329A2 (enExample)
CA (1) CA3014314A1 (enExample)
EA (1) EA201891799A1 (enExample)
IL (1) IL261046B (enExample)
MA (1) MA44008A (enExample)
MX (1) MX2018009752A (enExample)
SG (1) SG11201806750WA (enExample)
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US10766880B2 (en) 2020-09-08
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US10071988B2 (en) 2018-09-11
BR112018016329A2 (pt) 2018-12-18

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