JP6912199B2 - 免疫腫瘍溶解療法 - Google Patents

免疫腫瘍溶解療法 Download PDF

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JP6912199B2
JP6912199B2 JP2016536482A JP2016536482A JP6912199B2 JP 6912199 B2 JP6912199 B2 JP 6912199B2 JP 2016536482 A JP2016536482 A JP 2016536482A JP 2016536482 A JP2016536482 A JP 2016536482A JP 6912199 B2 JP6912199 B2 JP 6912199B2
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virus
deletion
tumor
trif
vaccinia virus
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JP2016527920A (ja
JP2016527920A5 (https=
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ソーン，スティーブン，ハワード
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ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション
ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24171—Demonstrated in vivo effect

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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Biotechnology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2016536482A 2013-08-22 2014-08-22 免疫腫瘍溶解療法 Active JP6912199B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361868978P 2013-08-22 2013-08-22
US61/868,978 2013-08-22
PCT/US2014/052308 WO2015027163A1 (en) 2013-08-22 2014-08-22 Immuno-oncolytic therapies

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JP2019133264A Division JP7021154B2 (ja) 2013-08-22 2019-07-19 免疫腫瘍溶解療法

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JP2016527920A JP2016527920A (ja) 2016-09-15
JP2016527920A5 JP2016527920A5 (https=) 2017-09-28
JP6912199B2 true JP6912199B2 (ja) 2021-08-04

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US (2) US11478518B2 (https=)
EP (3) EP4324918A3 (https=)
JP (3) JP6912199B2 (https=)
KR (1) KR102389240B1 (https=)
CN (1) CN105658795B (https=)
AU (1) AU2014308648B2 (https=)
CA (3) CA3213683A1 (https=)
CY (1) CY1126587T1 (https=)
DK (2) DK3778897T3 (https=)
EA (1) EA037582B1 (https=)
ES (2) ES2847305T3 (https=)
FI (1) FI3778897T3 (https=)
HR (1) HRP20240078T1 (https=)
HU (1) HUE066593T2 (https=)
IL (1) IL243996A0 (https=)
LT (1) LT3778897T (https=)
MD (2) MD4624C1 (https=)
MX (1) MX2016002257A (https=)
NZ (1) NZ716825A (https=)
PE (1) PE20160673A1 (https=)
PH (1) PH12016500329A1 (https=)
PL (1) PL3778897T3 (https=)
PT (1) PT3778897T (https=)
RS (1) RS65104B1 (https=)
SG (1) SG11201600960PA (https=)
SI (1) SI3778897T1 (https=)
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JP2022062171A (ja) * 2013-08-22 2022-04-19 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション 免疫腫瘍溶解療法

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JP2022062171A (ja) * 2013-08-22 2022-04-19 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション 免疫腫瘍溶解療法
US11478518B2 (en) 2013-08-22 2022-10-25 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Immuno-oncolytic therapies
JP7333431B2 (ja) 2013-08-22 2023-08-24 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション 免疫腫瘍溶解療法
US12514888B2 (en) 2013-08-22 2026-01-06 University of Pittsburgh—of the Commonwealth System of Higher Education Immuno-oncolytic therapies

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