JP6894439B2 - Ｃａｎｄｉｄａ種を検出するための方法及び組成物 - Google Patents

Ｃａｎｄｉｄａ種を検出するための方法及び組成物 Download PDF

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JP6894439B2
JP6894439B2 JP2018534978A JP2018534978A JP6894439B2 JP 6894439 B2 JP6894439 B2 JP 6894439B2 JP 2018534978 A JP2018534978 A JP 2018534978A JP 2018534978 A JP2018534978 A JP 2018534978A JP 6894439 B2 JP6894439 B2 JP 6894439B2
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sequence
seq
candida
specific
target
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JP2019501652A (ja
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アンジェラ エス． ハドソン，
アンジェラ エス． ハドソン，
デイモン ケー． ゲットマン，
デイモン ケー． ゲットマン，
アリス ジアン，
アリス ジアン，
バーバラ エル． イートン，
バーバラ エル． イートン，
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ジェン−プローブ・インコーポレーテッド
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2018534978A 2016-01-04 2017-01-04 Ｃａｎｄｉｄａ種を検出するための方法及び組成物 Active JP6894439B2 (ja)

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US201662274610P 2016-01-04 2016-01-04
US62/274,610 2016-01-04
PCT/US2017/012163 WO2017120216A2 (en) 2016-01-04 2017-01-04 Methods and compositions for detecting candida species

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JP2021075888A Active JP7201735B2 (ja) 2016-01-04 2021-04-28 Ｃａｎｄｉｄａ種を検出するための方法及び組成物
JP2021099927A Withdrawn JP2021137031A (ja) 2016-01-04 2021-06-16 Ｃａｎｄｉｄａ種を検出するための方法及び組成物
JP2023112150A Withdrawn JP2023118961A (ja) 2016-01-04 2023-07-07 Ｃａｎｄｉｄａ種を検出するための方法及び組成物
JP2025086503A Pending JP2025116051A (ja) 2016-01-04 2025-05-23 Ｃａｎｄｉｄａ種を検出するための方法及び組成物

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JP2021099927A Withdrawn JP2021137031A (ja) 2016-01-04 2021-06-16 Ｃａｎｄｉｄａ種を検出するための方法及び組成物
JP2023112150A Withdrawn JP2023118961A (ja) 2016-01-04 2023-07-07 Ｃａｎｄｉｄａ種を検出するための方法及び組成物
JP2025086503A Pending JP2025116051A (ja) 2016-01-04 2025-05-23 Ｃａｎｄｉｄａ種を検出するための方法及び組成物

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US (6) US11111549B2 (https=)
EP (3) EP3400309B1 (https=)
JP (5) JP6894439B2 (https=)
CN (1) CN108779499B (https=)
AU (4) AU2017205399C1 (https=)
CA (1) CA3010232A1 (https=)
WO (1) WO2017120216A2 (https=)

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CN116042902B (zh) * 2023-01-30 2025-07-25 上海仁度生物科技股份有限公司 一种同时检测六种念珠菌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针
CN116554998A (zh) * 2023-06-09 2023-08-08 鲲鹏基因（北京）科技有限责任公司 一种用于检测念珠菌的试剂盒
CN117106938B (zh) * 2023-08-31 2024-05-28 苏州创澜生物科技有限公司 一种用于检测阴道炎病原体的试剂、试剂盒及应用

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4786600A (en) 1984-05-25 1988-11-22 The Trustees Of Columbia University In The City Of New York Autocatalytic replication of recombinant RNA
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4868105A (en) 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
WO1988001302A1 (en) 1986-08-11 1988-02-25 Siska Diagnostics, Inc. Nucleic acid probe assay methods and compositions
US5541308A (en) 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
WO1989001050A1 (en) 1987-07-31 1989-02-09 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
US5639604A (en) 1987-09-21 1997-06-17 Gen-Probe Incorporated Homogeneous protection assay
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5585481A (en) 1987-09-21 1996-12-17 Gen-Probe Incorporated Linking reagents for nucleotide probes
DE3854029T2 (de) 1987-09-21 1995-10-26 Gen Probe Inc Homogener Abschirmungstest.
US5185439A (en) 1987-10-05 1993-02-09 Gen-Probe Incorporated Acridinium ester labelling and purification of nucleotide probes
US5124246A (en) 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5656207A (en) 1989-06-24 1997-08-12 Gen Probe Incorporated Detecting or quantifying multiple analytes using labelling techniques
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5516663A (en) 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5849481A (en) 1990-07-27 1998-12-15 Chiron Corporation Nucleic acid hybridization assays employing large comb-type branched polynucleotides
US5378825A (en) 1990-07-27 1995-01-03 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogs
JP3131222B2 (ja) 1991-12-24 2001-01-31 アイシス・ファーマシューティカルス・インコーポレーテッド ギャップを有する２′修飾オリゴヌクレオチド
US5424413A (en) 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
KR100249110B1 (ko) 1992-05-06 2000-04-01 다니엘 엘. 캐시앙 핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
WO1995003430A1 (en) 1993-07-23 1995-02-02 Gen-Probe Incorporated Methods for enhancing nucleic acid amplification
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5547861A (en) 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
JPH10500310A (ja) 1994-05-19 1998-01-13 ダコ アクティーゼルスカブ 淋菌及びトラコーマ クラミジアの検出のためのｐｎａ プローブ
DE69535240T2 (de) 1994-10-28 2007-06-06 Gen-Probe Inc., San Diego Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen
AU713667B2 (en) 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
CA2265474C (en) * 1996-09-16 2010-04-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods and compositions for the detection of candida spp.
AU775763B2 (en) * 1996-11-04 2004-08-12 Infectio Diagnostic (I.D.I.) Inc. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
EP0975807B1 (en) 1997-05-02 2006-09-27 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US6180340B1 (en) 1997-10-31 2001-01-30 Gen-Probe Incorporated Extended dynamic range assays
US6949367B1 (en) 1998-04-03 2005-09-27 Epoch Pharmaceuticals, Inc. Modified oligonucleotides for mismatch discrimination
AU762728B2 (en) 1998-07-02 2003-07-03 Gen-Probe Incorporated Molecular torches
SE0000061D0 (sv) * 2000-01-10 2000-01-10 Bjoern Herrmann A method for detection of pathogenic organisms
US20040022764A1 (en) * 2002-07-31 2004-02-05 Hanan Polansky Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease
CA2572472C (en) 2004-07-01 2013-08-13 Gen-Probe Incorporated Methods and compositions to detect nucleic acids in a biological sample
CA2957197C (en) 2004-08-27 2017-12-12 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
ES2610781T3 (es) 2004-09-14 2017-05-03 Argos Therapeutics, Inc. Amplificación de patógenos independiente de la cepa y vacunas para estos
US20060194240A1 (en) 2005-02-28 2006-08-31 Gen-Probe Incorporated Compositions and methods of detecting an analyte by using a nucleic acid hybridization switch probe
US9051601B2 (en) 2006-08-01 2015-06-09 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
EP1978111B1 (en) * 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa
US7595164B2 (en) * 2007-12-26 2009-09-29 Gen-Probe Incorporated Compositions and methods to detect Candida albicans nucleic acid
CN102292457B (zh) * 2008-11-25 2014-04-09 简·探针公司 检测小rna的组合物和方法及其用途
CN101886124A (zh) * 2010-05-25 2010-11-17 上海仁度生物科技有限公司 一种利用rna恒温扩增的结核分枝杆菌核酸检测试剂盒
EP2839038B1 (en) * 2012-04-20 2019-01-16 T2 Biosystems, Inc. Compositions and methods for detection of candida species
AU2013205122B2 (en) * 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
CN104232745B (zh) * 2013-06-14 2016-08-17 江苏默乐生物科技股份有限公司 用于RNaseP基因的荧光PCR检测试剂盒和检测方法
EP4299767A3 (en) * 2013-08-14 2024-03-27 Gen-Probe Incorporated Compositions and methods for detecting hev nucleic acid
US9234784B2 (en) 2013-10-25 2016-01-12 Rosemount Tank Radar Ab Frequency modulated radar level gauging
CA3224392A1 (en) * 2015-04-24 2016-10-27 Becton, Dickinson And Company Multiplex detection of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis

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AU2017205399C1 (en) 2023-06-15
AU2025204084A1 (en) 2025-06-26
US20210207227A1 (en) 2021-07-08
JP7201735B2 (ja) 2023-01-10
AU2023202340C1 (en) 2025-05-01
AU2017205399A1 (en) 2018-08-23
WO2017120216A2 (en) 2017-07-13
JP2021137031A (ja) 2021-09-16
AU2023202340B2 (en) 2025-01-23
US20230313320A1 (en) 2023-10-05
JP2021106618A (ja) 2021-07-29
US11313002B2 (en) 2022-04-26
JP2019501652A (ja) 2019-01-24
JP2023118961A (ja) 2023-08-25
EP3400309B1 (en) 2025-03-19
JP2025116051A (ja) 2025-08-07
CN108779499A (zh) 2018-11-09
EP4249609A3 (en) 2023-12-20
WO2017120216A3 (en) 2017-08-24
AU2017205399B2 (en) 2023-02-23
AU2023202333A1 (en) 2023-05-11
US20190002993A1 (en) 2019-01-03
EP4249610A3 (en) 2023-12-20
EP3400309A2 (en) 2018-11-14
AU2023202340A1 (en) 2023-05-11
CN108779499B (zh) 2023-08-11
US20210340634A1 (en) 2021-11-04
AU2025204084B2 (en) 2025-09-11
CA3010232A1 (en) 2017-07-13
EP4249609A2 (en) 2023-09-27
US20250154610A1 (en) 2025-05-15
US20230295745A1 (en) 2023-09-21
AU2023202333B2 (en) 2025-04-10
US12467101B2 (en) 2025-11-11
US11111549B2 (en) 2021-09-07
EP4249610A2 (en) 2023-09-27

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