JP6893914B2 - 光開裂可能標識を使用する抗原検出の方法 - Google Patents

光開裂可能標識を使用する抗原検出の方法 Download PDF

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JP6893914B2
JP6893914B2 JP2018506118A JP2018506118A JP6893914B2 JP 6893914 B2 JP6893914 B2 JP 6893914B2 JP 2018506118 A JP2018506118 A JP 2018506118A JP 2018506118 A JP2018506118 A JP 2018506118A JP 6893914 B2 JP6893914 B2 JP 6893914B2
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antigen
ligand
binding complex
photocleavable
sample
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JP2018523826A (ja
JP2018523826A5 (enExample
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ミミ ヘアリー
ミミ ヘアリー
チーイー チェン
チーイー チェン
ジンチュン ワン
ジンチュン ワン
ウェイドン ウ
ウェイドン ウ
ソフィア ペトリチェンコ
ソフィア ペトリチェンコ
ス チャン
ス チャン
ステイシー フライ
ステイシー フライ
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Agilent Technologies Inc
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Agilent Technologies Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302—Stain compositions
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    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies

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  • Clinical Laboratory Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2018506118A 2015-08-06 2016-08-08 光開裂可能標識を使用する抗原検出の方法 Active JP6893914B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562201978P 2015-08-06 2015-08-06
US62/201,978 2015-08-06
PCT/US2016/045981 WO2017024298A1 (en) 2015-08-06 2016-08-08 Antigen detection using photocleavable labels

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JP2018523826A JP2018523826A (ja) 2018-08-23
JP2018523826A5 JP2018523826A5 (enExample) 2019-10-17
JP6893914B2 true JP6893914B2 (ja) 2021-06-23

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US (2) US10942176B2 (enExample)
EP (1) EP3332253A1 (enExample)
JP (1) JP6893914B2 (enExample)
CN (1) CN107949790B (enExample)
AU (2) AU2016304599A1 (enExample)
BR (1) BR112018002525A2 (enExample)
CA (2) CA2993993C (enExample)
MX (1) MX2018001519A (enExample)
WO (1) WO2017024298A1 (enExample)

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CN110545847A (zh) * 2017-04-25 2019-12-06 达纳-法伯癌症研究所有限公司 用于肿瘤的靶向免疫疗法的组合物和方法
EP3431173A1 (en) * 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
WO2019152391A1 (en) * 2018-01-30 2019-08-08 Rush University Medical Center Sequential staining for multiplex analyses of tissues and cells
US20210228699A1 (en) * 2018-06-04 2021-07-29 Dana-Farber Cancer Institute, Inc. Compositions and methods for targeted immunotherapy
CN113272443B (zh) 2019-01-07 2025-01-10 安捷伦科技有限公司 用于单细胞中的基因组dna和基因表达分析的组合物和方法
JP2020143015A (ja) * 2019-03-06 2020-09-10 ソニー株式会社 粒子標識用試薬、粒子染色方法、及び顕微鏡システム
WO2020252488A2 (en) * 2019-06-14 2020-12-17 Akoya Biosciences, Inc. Multiplexed tissue imaging
CN111381034A (zh) * 2020-03-03 2020-07-07 武汉生之源生物科技股份有限公司 一种gpc-3抗体包被磁珠及其制备方法、试剂盒
WO2022076413A1 (en) * 2020-10-05 2022-04-14 Clara Biotech, Inc. Apparatus, system, and method for analyte release
CN112595845B (zh) * 2020-12-09 2022-10-21 深圳普门科技股份有限公司 透明质酸检测试剂盒及检测系统

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US6589736B1 (en) 1994-11-22 2003-07-08 The Trustees Of Boston University Photocleavable agents and conjugates for the detection and isolation of biomolecules
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US20090203023A1 (en) * 2008-02-11 2009-08-13 University Of Wyoming Concentrating Microorganisms in Aqueous Solution Prior to Selective Staining and Detection
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CN104024269B (zh) 2011-09-13 2017-05-24 激光基因公司 5‑甲氧基，3’‑oh未阻断，可快速光切割的终止核苷酸以及用于核酸测序的方法
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Publication number Publication date
WO2017024298A1 (en) 2017-02-09
MX2018001519A (es) 2018-08-01
US20170052175A1 (en) 2017-02-23
CA2993993C (en) 2022-01-04
CN107949790B (zh) 2024-07-26
AU2016304599A1 (en) 2018-02-15
AU2022210222B2 (en) 2025-09-18
JP2018523826A (ja) 2018-08-23
CA3138794C (en) 2024-01-23
US10942176B2 (en) 2021-03-09
CA2993993A1 (en) 2017-02-09
AU2022210222A1 (en) 2022-08-25
US20210181191A1 (en) 2021-06-17
BR112018002525A2 (pt) 2018-09-25
EP3332253A1 (en) 2018-06-13
CN107949790A (zh) 2018-04-20
CA3138794A1 (en) 2017-02-09

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