JP6880330B2 - 骨代替材料 - Google Patents

骨代替材料 Download PDF

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Publication number
JP6880330B2
JP6880330B2 JP2020532744A JP2020532744A JP6880330B2 JP 6880330 B2 JP6880330 B2 JP 6880330B2 JP 2020532744 A JP2020532744 A JP 2020532744A JP 2020532744 A JP2020532744 A JP 2020532744A JP 6880330 B2 JP6880330 B2 JP 6880330B2
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Japan
Prior art keywords
hap
cap
hydroxyapatite
bone
calcium phosphate
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JP2020532744A
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English (en)
Japanese (ja)
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JP2021506401A (ja
Inventor
ツィールマン,クラウディオ
バフラー,ミヒャエル
Original Assignee
ガイストリッヒ ファーマ アーゲー
ガイストリッヒ ファーマ アーゲー
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Priority to JP2021077751A priority Critical patent/JP7249376B2/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A61L24/0063Phosphorus containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/12Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
JP2020532744A 2017-12-14 2018-12-13 骨代替材料 Active JP6880330B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021077751A JP7249376B2 (ja) 2017-12-14 2021-04-30 骨代替材料

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17207235 2017-12-14
EP17207235.7 2017-12-14
PCT/EP2018/084783 WO2019115704A1 (en) 2017-12-14 2018-12-13 Bone substitute material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021077751A Division JP7249376B2 (ja) 2017-12-14 2021-04-30 骨代替材料

Publications (2)

Publication Number Publication Date
JP2021506401A JP2021506401A (ja) 2021-02-22
JP6880330B2 true JP6880330B2 (ja) 2021-06-02

Family

ID=60781527

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020532744A Active JP6880330B2 (ja) 2017-12-14 2018-12-13 骨代替材料
JP2021077751A Active JP7249376B2 (ja) 2017-12-14 2021-04-30 骨代替材料

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021077751A Active JP7249376B2 (ja) 2017-12-14 2021-04-30 骨代替材料

Country Status (18)

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US (2) US11351287B2 (enExample)
EP (1) EP3544643B1 (enExample)
JP (2) JP6880330B2 (enExample)
KR (1) KR102233325B1 (enExample)
CN (1) CN111465418B (enExample)
AU (1) AU2018382557B2 (enExample)
BR (1) BR112020010213B1 (enExample)
CA (1) CA3083852A1 (enExample)
DK (1) DK3544643T3 (enExample)
ES (1) ES2803976T3 (enExample)
HU (1) HUE050062T2 (enExample)
IL (1) IL275203B2 (enExample)
MX (1) MX2020005846A (enExample)
PL (1) PL3544643T3 (enExample)
PT (1) PT3544643T (enExample)
SG (1) SG11202004726YA (enExample)
TW (1) TWI852918B (enExample)
WO (1) WO2019115704A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3544643T (pt) 2017-12-14 2020-07-27 Geistlich Pharma Ag Material de substituição óssea
KR102636183B1 (ko) 2019-06-14 2024-02-13 가이스틀리히 파마 아게 골 대체 물질의 콜라겐 기질 또는 그래뉼레이트 블렌드
DE202021004032U1 (de) 2020-08-29 2022-10-10 BioScientific Designs d.o.o Ein steriles Medizinprodukt als Knochenersatz, Zubereitung und Verwendung

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EP2654816B1 (en) 2010-12-22 2015-02-11 Geistlich Pharma AG Bone substitute material
DE102011050183A1 (de) * 2011-05-06 2012-11-08 Aesculap Ag Oberflächenprofilierter Gitterkörper
GB201122405D0 (en) 2011-12-23 2012-02-08 Univ Aberdeen Calcium phosphate material
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CN111511415B (zh) 2017-12-14 2021-04-20 盖斯特里希医药公司 干式植入物组合物和可注射的水性植入物制剂
PT3544643T (pt) 2017-12-14 2020-07-27 Geistlich Pharma Ag Material de substituição óssea

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Publication number Publication date
AU2018382557A1 (en) 2020-06-11
CA3083852A1 (en) 2019-06-20
CN111465418A (zh) 2020-07-28
BR112020010213A2 (pt) 2020-08-18
WO2019115704A1 (en) 2019-06-20
ES2803976T3 (es) 2021-02-01
CN111465418B (zh) 2021-07-09
US20200016293A1 (en) 2020-01-16
PT3544643T (pt) 2020-07-27
US20190184059A1 (en) 2019-06-20
JP2021506401A (ja) 2021-02-22
HUE050062T2 (hu) 2020-11-30
RU2020118930A (ru) 2022-01-14
SG11202004726YA (en) 2020-07-29
TW201936216A (zh) 2019-09-16
DK3544643T3 (da) 2020-07-06
IL275203B (en) 2022-11-01
IL275203A (en) 2020-07-30
JP7249376B2 (ja) 2023-03-30
KR102233325B1 (ko) 2021-03-29
US10646615B2 (en) 2020-05-12
EP3544643B1 (en) 2020-05-13
PL3544643T3 (pl) 2020-12-28
TWI852918B (zh) 2024-08-21
US11351287B2 (en) 2022-06-07
JP2021118906A (ja) 2021-08-12
IL275203B2 (en) 2023-03-01
MX2020005846A (es) 2020-09-07
BR112020010213B1 (pt) 2020-12-22
RU2020118930A3 (enExample) 2022-02-25
AU2018382557B2 (en) 2024-05-02
EP3544643A1 (en) 2019-10-02
KR20200076753A (ko) 2020-06-29

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